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Statistical Monitoring of Clinical Trials - A Unified Approach (Hardcover, 1st ed. 2006. Corr. 2nd printing 2007) Loot Price: R3,719
Discovery Miles 37 190
Repayment Terms: R349 pm x 12*
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Statistical Monitoring of Clinical Trials - A Unified Approach (Hardcover, 1st ed. 2006. Corr. 2nd printing 2007): Michael A....

Statistical Monitoring of Clinical Trials - A Unified Approach (Hardcover, 1st ed. 2006. Corr. 2nd printing 2007)

Michael A. Proschan, K.K. Gordon Lan, Janet Turk Wittes

Series: Statistics for Biology and Health

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Loot Price R3,719 Discovery Miles 37 190 | Repayment Terms: R349 pm x 12*

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The approach taken in this book is, to studies monitored over time, what the Central Limit Theorem is to studies with only one analysis. Just as the Central Limit Theorem shows that test statistics involving very different types of clinical trial outcomes are asymptotically normal, this book shows that the joint distribution of the test statistics at different analysis times is asymptotically multivariate normal with the correlation structure of Brownian motion ("the B-value") - irrespective of the test statistic. Thus, this book offers statisticians an accessible, incremental approach to understanding Brownian motion as related to clinical trials.

General

Imprint: Springer-Verlag New York
Country of origin: United States
Series: Statistics for Biology and Health
Release date: November 2007
First published: 2008
Authors: Michael A. Proschan • K.K. Gordon Lan • Janet Turk Wittes
Dimensions: 235 x 155 x 19mm (L x W x T)
Format: Hardcover
Pages: 268
Edition: 1st ed. 2006. Corr. 2nd printing 2007
ISBN-13: 978-0-387-30059-7
Categories: Books > Medicine > General issues > Medical equipment & techniques > Medical research
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LSN: 0-387-30059-7
Barcode: 9780387300597

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