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Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics
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Genetic Toxicology of Complex Mixtures (Paperback, Softcover reprint of the original 1st ed. 1990)
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Genetic Toxicology of Complex Mixtures (Paperback, Softcover reprint of the original 1st ed. 1990)
Series: Environmental Science Research, 39
Expected to ship within 10 - 15 working days
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Contained in this volume are the proceedings of the international
conference on the "Genetic Toxicology of Complex Mixtures," held
from July 4-7, 1989, in Washington, DC. This meeting was a
satellite of the "Fifth International Conference on Environmental
Mutagens" and the seventh in a biennial series of conferences on
"Short-term Bioassays in the Analysis of Complex Environmental
Mixtures. " Our central objective in calling together key
researchers from around the world was to extend our knowledge of
the application of the methods of genetic toxicology and analytical
chemistry in the evaluation of chemical mixtures as they exist in
the environment. This conference emphasized the study of
genotoxicants in air and water, and the assessment of human
exposure and cancer risk. The latest strategies and methodologies
for biomonitoring of genotoxicants (including transformation
products) were described in the context of the ambient environment.
Source character ization and source apportionment were discussed as
an aid to understand ing the origin and relative contribution of
various kinds of complex mix tures to the ambient environment.
Similarly, investigations of genotoxi cants found in the indoor
environment (sidestream cigarette smoke) and in drinking water
(chlorohydroxyfuranones) were given special attention in terms of
their potential health impacts. New molecular techniques were
described to enable more precise quantitation of internal dose and
dose to-target tissues. The emphasis of presentations on
exposures/effects assessment was on integrated quantitative
evaluation of human exposure and potential health effects.
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