Theoretical and experimental advances in the techniques available
for solving crystal structures have led to the development of
several powerful techniques in crystallography for solving complex
structures, including those of proteins. Michael Woolfson and Fan
Hai-fu describe all the available methods and how they are used. In
addition to traditional methods such as the use of the Patterson
function and isomorphous replacement, and direct methods, the
authors include methods that use anomalous scattering and
observations from multiple-beam scattering. The fundamental physics
and mathematical analyses are fully explained. Practical aspects of
applying the methods are emphasised. This book will be valuable to
working crystallographers and to graduate students who are being
introduced to the problems of solving crystal structures.
General
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