This volume provides the most cutting edge technologies related to
the study of integrin activation and the characterization of their
vast interactomes. Chapters detail protocols on experimental
approached to quantify focal adhesion parameters, integrin
activation, and the lateral interaction of integrins with
transmembrane binding partners. Written in the highly successful
Methods in Molecular Biology series format, chapters include
introductions to their respective topics, lists of the necessary
materials and reagents, step-by-step, readily reproducible
laboratory protocols, and tips on troubleshooting and avoiding
known pitfalls. Authoritative and cutting-edge, The Integrin
Interactome: Methods and Protocols aims to give the reader a
multi-scale journey from single bonds inside protein structures to
the function of these crucial adhesion receptors at a whole
organism level in physiology and pathology.
General
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