The objective of the current study was to investigate the effect of
different blended vegetable oils having different levels and
profiles of polyunsaturated fatty acids (PUFA) on
hypercholesterolemia by analyzing the changes of lipid profile in
high cholesterol diet fed rats. Rats fed blended oils showed
significantly lower levels of total cholesterol (TC), total
triacylglycerol (TG) and total low density lipoprotein (LDL)
cholesterol as well as higher levels of high density lipoprotein
(HDL) cholesterol in comparison with animals fed HCD and
cholesterol free diet (CFD). Thus, oil blends under study may be
useful formulations for the treatment of hypercholesterolemia. In
addition to improving the lipid profile by lowering TC, TG and LDL
and increasing HDL, blending of vegetable oils can result in an
economic advantage of lower prices.
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