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Pheno-phospholipids and Lipo-phenolics - Novel Structured Antioxidants (Hardcover, 1st ed. 2021)
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Pheno-phospholipids and Lipo-phenolics - Novel Structured Antioxidants (Hardcover, 1st ed. 2021)
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Natural phenolics are powerful bioactive compounds, but their use
as antioxidant agents in lipid-based foodstuffs and cosmetics is
limited due to their hydrophilic traits. A promising technique to
overcome low solubility of phenolics is to increase their
hydrophobicity by grafting with lipophilic moiety to form
lipid-enriched phenolics (lipo-phenolics). Another way to enhance
the amphiphilic traits of phenolics is by lipophilization with
phospholipids in a suitable solvent to form phenolics-enriched
phospholipids (pheno-phospholipids). Both functionalized phenolics
(phenolipids) exhibit high bioavailability and antioxidative
potential. Functional phenolics-enriched phospholipids
(pheno-phospholipids) play an important role in enhancing the
functional properties of both phenolic compounds and phospholipids
in food for their use in nutrition and health. Phenolipids have
also found applications on an industrial scale, likely due to low
costs, the availability of starting material and safety. Recent
advances in the field of lipophilization allow accessing molecules
with high potency and targeted action covering a wide spectrum of
bioactivities. Owing to their cost and availability, phenolipids
find applications in niche sectors such as cosmetics and
pharmaceutics as well as in the novel food. This book reports on
the chemistry, preparation, and functionality of lipid-enriched
phenolics (lipo-phenolics), broadening their applications in food,
pharmaceuticals and cosmetics. The strategies of the
lipophilization of phenolics, the effect of modification on the
biological properties and potential applications of the resulting
lipo-phenolics are reviewed. The text also discusses the
preparation, physicochemical characteristics and functional
properties of phenolipids and phytosomes, including the latest
developments and their current industrial status.
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