Bipolar disorder (BD) is a chronic, severe, and highly disabling
illness, which is estimated to affect 1% of the population
worldwide. Recent studies have found that most bipolar patients
have high rates of functional and cognitive impairment,
contributing to the substantial psychosocial morbidity associated
with the disorder. Although there has been a considerable increase
in the understanding of the pathophysiological processes of Bipolar
Disorder, the underlying biology and common mechanisms of comorbid
physical and psychiatric disorders remain largely unclear. More
recently, there has been an increasing interest in the role of the
immune and inflammatory systems in mood disorders. It has been
demonstrated that mood episodes are associated with changes in
cytokines profiles and acute phase proteins such as
immunoglobulins, complement proteins, factor B, and
high-sensitivity C-reactive protein (CRP). The aim of the study was
to find out role of inflammatory markers in patients of Bipolar
Mood Disorder and its association with various demographic and
clinical factors.
General
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