Plants are reservoir of effective chemotherapeutics and can provide
valuable sources of natural antimicrobials. Bacteriocins are
natural antimicrobial peptides with interesting potential
applications in human health and exhibit a bactericidal mode of
action against related as well as unrelated microorganisms. In
present study Bougainvillea spectabilis and bacteriocins
susceptibility against Salmonella typhi was evaluated.
Bougainvillea spectabilis stem, leaves and flowers were extracted
in organic solvents through soxhlet and rotary evaporator. For the
bacteriocins screening, Lactococcus lactis was isolated from milk
samples. Disc diffusion method was used to determine the
antimicrobial activity. The results revealed that both the
Bougainvillea spectabilis and bacteriocins had antimicrobial
activity against S. typhi. The ethanolic and methanolic extracts of
flowers and leaves of Bougainvillea spectabilis were more active
against S. typhi. B. spectabilis and bacteriocins inhibition
activity proved them as the alternative antimicrobial agents
against human pathogens.
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