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Proteases and Their Receptors in Inflammation (Hardcover, 2011 ed.)
Loot Price: R4,267
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Proteases and Their Receptors in Inflammation (Hardcover, 2011 ed.)
Series: Progress in Inflammation Research
Expected to ship within 10 - 15 working days
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Proteases are everywhere from prokaryotes to eukaryotes, from virus
to bacteria and in all human tissues, playing a role in many
biological functions. Among these functions, the inflammatory
reaction is of particular interest. In inflamed tissues, proteases
can have a microbial and/or host origin and are involved not only
in tissue remodeling, but also in specific signaling to resident or
inflammatory cells, thereby contributing to the innate immune
response. This volume presents all advances in our knowledge of the
role proteases and their inhibitors play in various diseases
associated with inflammatory response. Mechanisms involved in
protease signaling to cells are presented, and the different types
of proteases that are present at inflammatory sites and their
effects on the course of inflammation are discussed. Finally, the
evidence for considering proteases and their receptors as potential
molecular targets for therapeutic interventions in the treatment of
inflammatory diseases is discussed in the context of specific organ
inflammatory pathologies (the lung, gastrointestinal tract, skin,
joints, etc.).
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