The National Institutes of Health Publication 05-5051, Cancer
Clinical Trials: The In-Depth Program provides health care
professionals and others with a more in-depth understanding of
clinical trials. Research supports that the public understands very
little about clinical trials. Some people are fearful of being
"guinea pigs," even though participants in clinical trials receive
high-quality care. Other people are not aware of clinical trials as
an option, do not understand how they work, or do not have access
to them. Likewise, health care professionals may be unaware of
appropriate clinical trials, may not want to refer people out of
their practice, may believe that standard therapy is best, or may
think that getting involved in clinical trials will add an undue
administrative burden to their work. Today's standard cancer
treatments were yesterday's clinical trials. Successful clinical
trials have: Increased survival rates of participants with
testicular cancer, breast cancer, leukemia, and lymphoma; Decreased
morbidity associated with the surgical treatment of many cancers;
Resulted in the development of new compounds and techniques to
reduce the side effects of cancer therapies. This guide is designed
to familiarize health care professionals and others with the ins
and outs of clinical trials. It describes how: The clinical trial
process works, Trials are designed to obtain particular
information, Clinical trials advance standard cancer treatment,
Trial participants are safeguarded, People might face obstacles to
participating in clinical trials, To find a local clinical trial.
After reading the guide and reviewing the case study, the reader
will be better able to manage issues related to clinical trials.
The reader should be able to: Discuss clinical trials as potential
treatment or preventive options, Answer people's questions and
allay their fears about clinical trials, Locate and refer people to
accessible clinical trials, Ultimately help advance the early
detection, treatment, and eventual prevention of cancer.
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