The National Institutes of Health Publication 02-5050, Cancer
Clinical Trials: The Basic Workbook, features information about and
different aspects of clinical trials. The self-modulated workbook,
with its accompanying activities, will help readers understand why
cancer clinical trials are important, how they work, how
participant safety is protected, as well as some of the reasons so
few adults participate in these trials. It is designed for
individuals who want to develop a basic understanding of clinical
trials. Scientific discoveries are providing more and more insights
into the causes of cancer. Many of these successes are limited to
the laboratory and have yet to be translated into improved care for
people with cancer. Clinical trials are a critical part of the
research process. Clinical trials help to move basic scientific
research from the laboratory into treatments for people. By
evaluating the results of these trials, we can find better
treatments and ways to prevent, detect, and treat cancer. But very
few adults with cancer-only 3 percent-participate in clinical
trials. We need to test the best cancer prevention, detection, and
treatment ideas in the shortest time possible, and this can only
happen if more people participate in clinical trials. We know that
most people understand very little about clinical trials. National
Cancer Institute (NCI) research has shown that the general public
is either unaware of clinical trials as a treatment/ prevention
option or misinformed about the clinical trial process. The reasons
for this lack of understanding are complex, and there is no simple
solution. We do know, however, that there are many barriers that
discourage both physicians and potential participants from taking
part in clinical trials. By reading this workbook, you are already
helping to overcome some of these barriers. Whether you are a
cancer survivor, someone who works with people with cancer, or
someone who is touched by cancer in another way-this workbook can
help answer your questions about clinical trials. It will help you
understand why cancer clinical trials are important, how they work,
how the participants' safety is protected, and some of the reasons
why more adults don't participate in trials. With this information,
you can help people in your community make informed decisions about
their cancer treatment and prevention options, including the option
of participating in a clinical trial.
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