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Proteases - Functions, Mechanisms and Uses (Hardcover)
Loot Price: R4,819
Discovery Miles 48 190
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Proteases - Functions, Mechanisms and Uses (Hardcover)
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Proteases or proteinases have a wide application in different
industrial processes including cheese production, meat
tenderization, production of protein hydrolysates, silver recovery
and silk; in many other fields including biotechnological, baking,
textiles, pharmaceutical and leather industries and also, as an
additive to detergents and in bioremediation procedures. These
enzymes are present in plants, animals and microorganisms
(protozoa, bacteria, fungus and some types of algae and viruses).
Considering the wide applications of these enzymes, it is necessary
to know their functions, origin (plants, animals, bacteria and
fungus), classification and characteristics, action mechanisms,
their specific target substrates and products obtained in the
reactions that these enzymes catalyze, as well as their optimal
temperature and pH of activity and stability. The book provides an
overview of the latest knowledge about the functions and action
mechanisms of protease enzymes and their applications in different
industrial fields. It addresses four important aspects: the main
characteristics of proteases of different origins, the design of
emerging technologies for production of novel proteases with
enhanced specificity, stability and catalytic activity for a wide
industrial application, utilization of proteases to produce
functional foods and the use of protease inhibitors to control or
block the activity of these enzymes for preventing diseases in
humans and animals. It was felt necessary to include a chapter
based on the use of bioinformatics resources (databases, tools,
visualization and data analysis) to provide a better understanding
of proteases and their functions at the molecular level. Although
production and application of bacterial and fungal proteases have
long been reported, little is known about the proteases produced by
insects (mainly those economic and medically important species),
organisms inhabiting marine environments and protozoa, their action
mechanisms, properties and physiology. This knowledge is important
for designing new strategies for herbivory insect control to avoid
the transmission or development of pathogens in their corresponding
entity hosts (in case of insect digestive proteases), or designing
specific antiparasitic drugs to block the action of proteases and
avoid colonization and imminent parasitism (in case of protozoa
proteases). In addition, the knowledge about the integrity and
function of marine proteases under extreme reaction conditions
could facilitate their application in a wider processing conditions
than the terrestrial proteases.
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