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Uses of Inorganic Chemistry in Medicine (Hardcover)
Loot Price: R2,364
Discovery Miles 23 640
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Uses of Inorganic Chemistry in Medicine (Hardcover)
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Total price: R2,384
Discovery Miles: 23 840
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Metal-based drugs are a commercially important sector of the
pharmaceutical business, yet most bioinorganic textbooks lack the
space to cover comprehensively the subject of metals in medicine.
Uses of Inorganic Chemistry in Medicine approaches an understanding
of the topic in a didactic and systematic manner. The field of
inorganic chemistry in medicine may usefully be divided into two
main categories - drugs which target metal ions in some form,
whether free or protein-bound, and secondly, metal-based drugs
where the central metal ion is usually the key feature of the
mechanism of action. This latter category can further be subdivided
into pharmacodynamic and chemotherapeutic applications, as well as
those of imaging. The book summarises the chemical and biological
studies on clinically used agents of lithium, gold and platinum, as
well as highlighting the research on prospective new drugs,
including those based on vanadium and manganese. The coverage
allows a clear distinction between pharmacodynamic and therapeutic
properties of metal-based drugs and focuses not only on those
clinical agents in current use, but also on new drugs and uses.
This book serves to fill an important niche, bridging bioinorganic
and medicinal chemistry and will undoubtedly be of use to senior
undergraduates and postgraduates, as well as being an invaluable
asset for teachers and researchers in the discipline.
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