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Bioactive Heterocycles VI - Flavonoids and Anthocyanins in Plants, and Latest Bioactive Heterocycles I (Hardcover, 2008 ed.)
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Bioactive Heterocycles VI - Flavonoids and Anthocyanins in Plants, and Latest Bioactive Heterocycles I (Hardcover, 2008 ed.)
Series: Topics in Heterocyclic Chemistry, 15
Expected to ship within 10 - 15 working days
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As part of the series Topics in Heterocyclic
Chemistry,thisvolumetitledBio- tiveHeterocyclesII
presentscomprehensiveandup-to-datereviewsonselected
topicsconcerning?avonoidsandanthocyaninsinplants,andheterocyclessuch
as bioactive phenothiazines, phenoxazines, and related compounds.
The v- ume isseparated into two sections mainly concentrating
onthese two topics. There are abundant and diverse ?avonoids with
carbohydrates and lipids, alkaloids (betalain alkaloids and other
alkaloids), phenols (chromones, c-
marins,lignans,quinines,andotherphenolics),terpenoids(monoterpenoids,
sesquiterpene lactones, triperpenoid saponins, carotenoids, and
other t- penoids), and minerals as micronutritionalphytochemicals
in fruits and v- etables of our daily diets. Among these
phytochemicals, the ?avonoids have speci?c functionality in
relation to age-related diseases such as hypertension,
diabetes,cardiacinfarction,cataracts,andcancer.Theauthorsofeachchapter
inthe?rst sectionhave presented their evidence in
relationtothemechanism ofthepreventative andtherapeutic ability
ofthecompounds. The ?rst chapter, "Functionality of Anthocyanins as
Alternative Medicine"
byNoboruMotohashiandHiroshiSakagami,presentstheirantioxidantme-
anism for anthocyanidins, which are present in common foods. It is
possible that anthocyanins may have been used both preventatively
and clinically as part of many "folklore medicines" worldwide and
may have provided heal-
carebene?tssincetheappearanceofmankindsome7.5millionyearsago.The
review willinform the reader as to their functionalityand
mechanism. The second chapter, "Bioactive Mechanism of Interaction
between Ant- cyanins and Macromolecules Like DNA and Proteins" by
Seetharamappa J- dappagari, Noboru Motohashi, Mamatha
P.Gangeenahalli, and James H. N- smith, presents the biological
activities of anthocyanins, and the interactions of anthocyanins
with DNA and protein. Anthocyanins might protect against damage to
health by some types of harmful oxidants through various me- anisms
such as their antioxidative activity, protein active site binding,
and chelating complex formation. The review presents the
interesting interactive mechanism of anthocyanin-DNA complex
formation.
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