GAPDH: Biological Properties and Diversity (Hardcover, 2013 ed.)

The book represents a comprehensive review and synthesis of the biomedical literature that spans over a half-century on a single protein called glyceraldehyde 3-phosphate dehydrogenase (or, GAPDH). Due to the protein's involvement in a vast array of cellular activities, GAPDH is of interest to the cell biologist, immunologist, virologist, biochemist etc. The protein has a significant role in fertility, cancer and neurodegeneration, suggesting that this book can be a vital resource for drug development. GAPDH function may provide insight into anesthesia. Furthermore, GAPDH is highly conserved meaning that the protein found in microorganisms, such as pathogens, remained relatively unchanged in evolution. Pathogens use GAPDH as a virulence factor, offering a unique challenge in developing anti-microbial agents that target this protein. To the evolutionary biologist, a book on the multi-functionality of GAPDH provides a focal point for a cogent discussion on the very origin of life.

General

Imprint:	Springer
Country of origin:	Netherlands
Series:	Advances in Experimental Medicine and Biology, 985
Release date:	July 2012
First published:	2013
Authors:	Norbert W. Seidler
Dimensions:	254 x 178 x 23mm (L x W x T)
Format:	Hardcover
Pages:	295
Edition:	2013 ed.
ISBN-13:	978-9400747159
Categories:	Books > Medicine > General issues > Medical equipment & techniques > Medical research Books > Medicine > Nursing & ancillary services > Biomedical engineering > General Books > Science & Mathematics > Biology, life sciences > Cellular biology > General
LSN:	9400747152
Barcode:	9789400747159

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