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Principles of Molecular Regulation (Paperback, Softcover reprint of the original 1st ed. 2000)
Loot Price: R3,625
Discovery Miles 36 250
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Principles of Molecular Regulation (Paperback, Softcover reprint of the original 1st ed. 2000)
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THE STATE oF HoRMONE AcTioN levels were induced in concert with
ligand occupa tion of certain membrane receptors and this second
AND MoLECULAR REGULATION messenger (cAMP) was postulated to
initiate intra cellular phosphorylation of unknown targets. At
Molecular Endocrinology and Regulation is a this point, the field
ofPeptide Hormone Action also burgeoning field, having experienced
a remarkable came into being. period of growth since the late
1960s. At that time, These fields developed together for much ofthe
there was no field of Hormone Action. The prevail next decade.
Hormone Action Conferences invari ing view of how hormones worked
ranged from ably contained talks on both types of receptors and
effects on membrane transport of nutrients and progress was rapid
and in concert with the explo precursors for RNA and protein
synthesis, to effects sion molecular biology. In the steroid field,
on the translation of mRN A at the level of ribo progress was more
rapid initially, but by the mid somes. Therewas, however,
asmallcadreofvoices 1980s, the peptide field attained equal
mechanistic that predicted a possible nuclear action on mRN A
status and the source of specialized conferences of synthesis. The
first such paper was presented at the national endocrine meetings
in 1967 and dealt with its own. Steroid hormone action
investigators concen hormonal stimulation of oviductal protein
synthe tratedonfirst understanding the "pathway" of action sis. It
was about this time that a small group of for their hormones."
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