Nitroarenes, 4th - Occurence, Metabolism and Biological Impact - International Conference Proceedings (Hardcover, New)

Epidemiology and Carcinogenesis.- Evidence from Animal Studies for the Carcinogenicity of Inhaled Diesel Exhaust.- Interpretation of Carcinogenicity and Effective Dose in Chronic Exposures of Rats to High Diesel Exhaust Concentrations.- Carcinogenicity of Dinitroarenes in Rat Lung.- In Vivo Metabolism and Genotoxic Effects of the Air Pollutant and Marker for Nitro-PAH's, 2-Nitrofluorene.- Chemistry, Detection, and Occurrence.- Nitroarenes: Their Detection, Mutagenicity and Occurrence in the Environment.- The Atmospheric Formation of Nitroarenes and Their Occurrence in Ambient Air.- Metabolism of 1-Nitropyrene Oxides and Effect of Nitrogen Dioxide on Arene Activation.- Molecular Mechanisms.- Mutagenic and Biochemical Consequences of the Reaction of Arylamines with DNA.- Mutagenesis Induced by a Single Acetylaminofluorene Adduct within the Narl Site is Position Dependent.- Unusual Hydrogen Bonding Patterns in 2-Aminofluorene (AF) and 2-Acetylaminofluorene (AAF) Modified DNA.- DNA Adduct Formation during Chronic Administration of an Aromatic Amine.- Aerial Oxidation of Acetylaminofluorene-Derived DNA Adducts.- Mutations and Homologous Recombination Induced by N-Substituted Aryl Compounds in Mammalian Cells.- Comparison of the Mutagenic Potency of DNA Adducts Formed by Reactive Derivatives of Aflatoxin, Benzidine and 1-Nitropyrene in a Plasmid System.- Mutations Induced in the lacI Gene of E. coli by 1-Nitroso-8-Nitropyrene and Furylfuramide: The Influence of Plasmid pKM101 and Excision Repair on the Mutational Spectrum.- DNA Adduct Formation by 1-Nitropyrene 4,5- and 9,10-Oxide.- Nitropolycyclic Aromatic Hydrocarbons and Diesel Exhaust: Potential Role of DNA Binding in Carcinogenicity.- Validation/Application of 32?-Postlabeling Analysis for the Detection of DNA Adducts Resulting from Complex Air Pollution Sources Containing PAHs and Nitrated PAHs.- Analysis of NO2-PAH DNA Adducts by Mass Spectrometry.- Metabolism.- Generation of Reactive Intermediates from 2-Nitrofluorene that Bind Covalently to DNA, RNA and Protein In Vitro and In Vivo in the Rat.- Activation of Carcinogenic N-Arylhydroxamic Acids by Peroxidase/H2O2/Halide Systems: Route to C-Nitroso Aromatics.- Biochemical Studies on the Putative Nitroso Metabolite of Chloramphenicol: A New Model for the Cause of Aplastic Anemia.- Mechanisms of FANFT/ANFT Induced Bladder Cancer.- Mutagenic Arylazides, Arylnitrenes, Arylnitrenium Ions.- Products Obtained by In Vitro Reaction of 4,5-Epoxy4,5-Dihydro-1-Nitropyrene with DNA.- Oxidative Metabolism of Nitrated Polycyclic Aromatic Hydrocarbons in Mammalian Cell Fractions.- Metabolic Activation of 6-Nitrochrysene and 6-Aminochrysene In Vitro and In Vivo.- Summary.- The Possible Role of Nitroarenes in Human Cancer.- Abstracts Presented at the Meeting.- Contributor Index.

General

Imprint:	Kluwer Academic / Plenum Publishers
Country of origin:	Netherlands
Series:	Environmental Science Research, 40
Release date:	November 1990
First published:	1991
Volume editors:	Paul C. Howard • Etc
Dimensions:	230mm (L)
Format:	Hardcover
Pages:	340
Edition:	New
ISBN-13:	978-0-306-43694-9
Categories:	Books > Science & Mathematics > Biology, life sciences > Biochemistry > General
LSN:	0-306-43694-9
Barcode:	9780306436949

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