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Transcription Factors - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2010)
Loot Price: R4,467
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Transcription Factors - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2010)
Series: Methods in Molecular Biology, 647
Expected to ship within 10 - 15 working days
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In the last few years, significant breakthroughs in transcription
research expanded our appreciation for the complexity of molecular
controls on gene expression in mammalian cells. In Transcription
Factors: Methods and Protocols, experts in the field describe
state-of-the-art approaches that investigators can use to probe
critical mechanisms underlying transcription factor
nuclear-cytoplasmic trafficking as well as to assess the functional
impact of post-translational modifications on transcription factor
function. The chapters are written by prominent scientists, many of
whom developed these methods, and highlight protocols that focus on
specific transcription factor family members with particular
relevance to human disease. Composed in the highly successful
Methods in Molecular Biology (TM) series format, each chapter
contains a brief introduction, step-by-step methods, a list of
necessary materials, and a Notes section which shares tips on
troubleshooting and avoiding known pitfalls. Comprehensive and
current, Transcription Factors: Methods and Protocols compiles the
latest techniques for elucidating controls on transcription factor
intracellular localization and activity, and consequently is unlike
any other methods-based text on transcriptional regulation today.
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