In this thoroughly updated and revised edition of his much praised
book, Paul L. Wood and a panel of leading researchers capture these
new developments in a masterful synthesis of what is known today
about the inflammatory mediators and cells involved in
neurodegenerative diseases. This second edition contains extensive
updates on the mediators produced by microglia and their role in
neuroinflammatory-induced neuronal lysis. There is also increased
coverage of the animal models used in the study of
neuroinflammatory mechanisms, of the new imaging methods that allow
the noninvasive evaluation of microglial activation in human
neurodegernerative disorders, and of the role of neuroinflammation
in amyloid-dependent neuronal lysis.
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