This volume comprehensively covers new technologies and
methodologies that have appeared for the study of mouse
development.
This volume is an update of volume 225 of MIE, "Guide to
Techniques in Mouse Development," edited by P.M. Wassarman and M.L.
DePamphilis and published in 1993. During the past 17 years many
new technologies or methodologies have appeared for the study of
mouse development and this volume comprehensively covers these,
including: new techniques for the cryopreservation of gametes and
embryos, production of transgenic and null (knockout) animals (use
of ES cells), generation of conditional/inducible mutant animals,
use of gene-trap mutagenesis, analysis of allele-specific
expresion, use of new reporter constructs, humanizing of transgenic
animals, transcript profiling of mouse development, imaging of
mouse development, rederivation of animals and use of mouse
genomics.
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