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Forensic Practitioner's Guide to the Interpretation of Complex DNA Profiles (Paperback)
Loot Price: R2,597
Discovery Miles 25 970
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Forensic Practitioner's Guide to the Interpretation of Complex DNA Profiles (Paperback)
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Over the past twenty years, there's been a gradual shift in the way
forensic scientists approach the evaluation of DNA profiling
evidence that is taken to court. Many laboratories are now adopting
'probabilistic genotyping' to interpret complex DNA mixtures.
However, current practice is very diverse, where a whole range of
technologies are used to interpret DNA profiles and the software
approaches advocated are commonly used throughout the world.
Forensic Practitioner's Guide to the Interpretation of Complex DNA
Profiles places the main concepts of DNA profiling into context and
fills a niche that is unoccupied in current literature. The book
begins with an introduction to basic forensic genetics, covering a
brief historical description of the development and harmonization
of STR markers and national DNA databases. The laws of statistics
are described, along with the likelihood ratio based on
Hardy-Weinberg equilibrium and alternative models considering
sub-structuring and relatedness. The historical development of low
template mixture analysis, theory and practice, is also described,
so the reader has a full understanding of rationale and
progression. Evaluation of evidence and statement writing is
described in detail, along with common pitfalls and their
avoidance. The authors have been at the forefront of the
revolution, having made substantial contributions to theory and
practice over the past two decades. All methods described are
open-source and freely available, supported by sets of test-data
and links to web-sites with further information. This book is
written primarily for the biologist with little or no statistical
training. However, sufficient information will also be provided for
the experienced statistician. Consequently, the book appeals to a
diverse audience
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