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Insulin Resistance - Childhood Precursors of Adult Disease (Hardcover, 2nd ed. 2020)
Loot Price: R3,209
Discovery Miles 32 090
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Insulin Resistance - Childhood Precursors of Adult Disease (Hardcover, 2nd ed. 2020)
Series: Contemporary Endocrinology
Expected to ship within 12 - 17 working days
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Now in a revised and expanded second edition, this unique text
presents topics related to insulin resistance in youth and its
consequences across the lifespan. In the first section of the book
examining epidemiology, the contributors review controversies over
the definition of insulin resistance in children and what is known
about how insulin resistance in youth differs from adults, the
measurement of insulin resistance in youth in the research and
clinical settings, and current knowledge regarding the epidemiology
of insulin resistance in the pediatric population. The second
section of the book explores pathophysiology, including current
knowledge of the molecular, metabolic, and physiologic mechanisms
of insulin resistance, the unique pathophysiology of pregnancy and
puberty, the contributions of the prenatal and early childhood
environment to the development of insulin resistance, and adipose
and biochemical mediators. This section concludes with discussion
of the relationship between insulin resistance and cardiovascular
disease and liver disorders. A third section, new to this second
edition, explores insulin resistance in unique models: intrauterine
growth restriction and girls with polycystic ovary syndrome and
metabolic syndrome. The final section of the book explores the
concepts of treatment through medications directed at insulin
sensitivity, as well as exercise, weight loss medications and
consequences of bariatric surgery. Insulin Resistance: Childhood
Precursors of Adult Disease, Second Edition provides up-to-date
reviews of all of these areas, providing the reader with a current
perspective on issues in insulin resistance in youth, an emerging
risk factor for disease across the lifespan, that will spur
continued interest in the topic on the part of clinicians and
researchers, perhaps promoting new points of view and creative
approaches to this daunting challenge.
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