Over the past 25 years, biobanks of human specimens have become a
cornerstone for research on human health and have empowered the
"omics "revolution that characterizes biomedical science in the
XXIst Century. Today, biobanking of human specimens is a critical
component of the interface between clinical practice and
translational research, supporting the discovery and validation of
new biomarkers of disease etiology, risk, early detection,
diagnosis, prognosis, prediction and relapse. With the development
of personalized medicine, biobanking of cryopreserved specimens has
become standard practice in order to investigate genetic,
transcriptomic, proteomic, metabolomics and immunological
biomarkers useful to inform caregivers for therapeutic decisions.
Data generated from biobanked specimens represent a rapidly growing
and highly valuable resource, participating in the emergence of Big
Data Medicine. With the development of large computing capabilities
and artificial intelligence, data associated with biobanked
specimens constitute a unique resource for the discovery and
validation of new biomarkers and therapeutically actionable
targets. Interconnecting, interoperating and sharing this data have
become major issues for national health systems, raising enormous
stakes as well as major societal, legal and cybersecurity
challenges in terms of compliance with the protection of personal
sensitive information. This book project is the second part of an
initiative launched in 2012 to produce a published corpus of
knowledge encompassing all aspects of human biobanking as a central
practice for research and medicine. The first volume, published in
2017, is entitled: Human Biobanking: Principles and Practice. This
first volume compiled a series of high level contributions
overseeing the main developments that carried the progression of
human biobanking as a research and biotechnological field over the
past two decades. This new book project will constitute de facto
Volume 2 of the same initiative, under the title: Biobanking of
Human Biospecimens: lessons from 25 years of biobanking experience.
Hence, the two volumes will share the same generic title
(Biobanking of Human Biospecimens), with different subtitles,
making clear that the two volumes are interrelated while
highlighting their specificities in terms of what they actually
cover. As a result, the two books are "twins" but can also be used
independently of each other. The overarching aim of the two volumes
of Biobanking of Human Biospecimens is to provide a published
"one-stop shop" for state-of-the-art information on what
constitutes the field of human biobanking, from conception of a
biobank, standard operating procedures, ethical and societal
aspects, governance, networking, interoperability and economic
sustainability. This inclusive publication concept meets the needs
of a vast readership, including scientists, doctors and technical
staffs who are directly involved in biobanking operations,
scientists in other disciplines that heavily rely on biobanking
(such as genomics or proteomics), stakeholders and policy makers,
and of course students for whom biobanking is becoming an important
part of the training curriculum. So far, there has been a lack of
major textbooks on biobanking. Documentation for biobanking is
widely available through numerous publications, regulatory
documents published by International or Governmental Agencies, and
sets of recommendations essentially accessible through the
Internet. However, it is difficult to access a single, top-of-the
shelf reference that provides at a glance a large coverage of all
aspects of human biobanking. Fulfilling this need is the main
origin of the concept for this back-to-back publication project. To
our knowledge, there is currently no other publication project with
the same breath and scope as this one in the field of biobanking.
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