Clinical pharmacology plays an important role in today's medicine.
Due to the high sensitivity, selectivity, and affordability of a
mass spectrometer (MS), the high performance liquid chromatography
- mass spectrometry (LC-MS) analytical technique is widely used in
the determination of drugs in human biological matrixes for
clinical pharmacology. Specifically, LC-MS is used to analyze:
anticancer drugs antidementia drugs antidepressant drugs
antiepileptic drugs antifundal drug antimicrobial drugs
antipsychotic drugs antiretroviral drugs anxiolytic/hypnotic drugs
cardiac drugs drugs for addiction immunosuppressant drugs mood
stabilizer drugs This book will primarily cover the various methods
of validation for LC-MS techniques and applications used in modern
clinical pharmacology.
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