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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences

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The Histamine H3 Receptor, Volume 30 - A Target for New Drugs (Hardcover) Loot Price: R4,446

Discovery Miles 44 460

Repayment Terms: R417 pm x 12*

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The Histamine H<INF>3</INF> Receptor, Volume 30 - A Target for New Drugs (Hardcover): R. Leurs, H. Timmerman

The Histamine H3 Receptor, Volume 30 - A Target for New Drugs (Hardcover)

R. Leurs, H. Timmerman

Series: Pharmacochemistry Library

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Loot Price R4,446 Discovery Miles 44 460 | Repayment Terms: R417 pm x 12*

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In the early eighties when the H3 receptor was identified, many thought that an H3 ligand, an agonist or an antagonist, would become available as a therapeutic agent. This has not occurred. The reason for this could be the fact that many investigators consider histamine mainly, if not only, as a mediator present in for example mast cells being released during allergic events. However, it has become apparent that histamine is an important neurotransmitter. Its role in the nervous system, especially in the central part of it, is rather extensive.

The H3 receptor is mainly found as a presynaptic one, both on histaminergic neurons (the auto-type) and on other neuronal systems (the hetero-type). Both the H3 agonist and the H3 antagonist cause important pharmacological effects. Several ligands have become available now, including radiolabelled analogues.

In this book, the current state of affairs with regards to the medicinal chemistry and pharmacology of the H3 receptor and the several ligands available are presented by a number of experts in the field. The book presents an extended review of what has happened since the first H3 paper appeared. The editors hope that publication of this work will lead to an increase in interest of both academia and industry for the H3 receptor, especially as a target for drug development.

General

Imprint:	Elsevier Science Ltd
Country of origin:	United Kingdom
Series:	Pharmacochemistry Library
Release date:	December 1998
First published:	December 1998
Editors:	R. Leurs • H. Timmerman
Dimensions:	240 x 165mm (L x W)
Format:	Hardcover
Pages:	290
ISBN-13:	978-0-444-82936-8
Categories:	Books > Medicine > Other branches of medicine > Pharmacology > General Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology Promotions
LSN:	0-444-82936-9
Barcode:	9780444829368