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Tracer Kinetics and Physiologic Modeling - Theory to Practice. Proceedings of a Seminar held at St. Louis, Missouri, June 6, 1983 (Paperback)
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Tracer Kinetics and Physiologic Modeling - Theory to Practice. Proceedings of a Seminar held at St. Louis, Missouri, June 6, 1983 (Paperback)
Series: Lecture Notes in Biomathematics, 48
Expected to ship within 10 - 15 working days
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These lectures were prepared by the authors for Seminars to be held
on June 6, 1983, in St.Louis, Missouri, under the spon- sorship of
the Radiopharmaceutical Science Council of the So- ciety of Nuclear
Medicine . All manuscript? were refereed . Tracer kinetics and the
modeling of physiological and bio- chemical processes in vivo are
the focus of a contemporary di- rection in biochemical research.
Recent advances in instrumen- tation (especially positron emission
tomography and digital autoradiography) and parallel developments
in the production of short-lived radionuclides and rapid synthetic
chemistry to pre- pare tracers that probe metabolism, flow,
receptor-ligand kinetics, etc., are responsible for new scientific
frontiers. These developments, coupled with biomathematics and
computer science, make it possible to quantitatively evaluate
tracer kinetic models in animals and man. (The choice of animal
models in radiotracer design and tracer kinetics is the subject of
a book edited by R.M.Lambrecht and W.C.Eckleman in press at Sprin-
ger Verlag.) Tracer kinetics and physiological modeling is truly
multi- disciplinary, as evidenced by the intellectual diversity and
international representation observable in the list of contri-
butors . The lectures outline and attempt to show the transition
from the theoretical description to the practical application of
modeling for understanding normal and pathological processes .
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