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Books > Science & Mathematics > Chemistry > Organic chemistry
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Modern Methods in Stereoselective Aldol Reactions (Hardcover)
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Modern Methods in Stereoselective Aldol Reactions (Hardcover)
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The selective formation of bondings between molecules is one of the
major challenges in organic chemistry, and the so-called aldol
reaction is one of the most important for this purpose. These
reactions are a highly useful tool for developing such novel
substances as natural products and pharmaceuticals.
Likes its highly successful and much appreciated predecessor,
"Modern Aldol Reactions," this ready reference provides a
systematic overview of methodologies for installing a required
configuration during an aldol addition step, but shifts the focus
so as to cover the latest developments.
As such, it presents a set of brand new tools, including vinylogous
Mukaiyama-aldol reactions and substrate-controlled aldol reactions,
as well as asymmetric induction in aldol additions. Furthermore,
new developments in existing stereoselective aldol additions are
described, such as the deployment of supersilyl groups or
organocatalyzed aldol additions. All of these methodologies are
presented in the context of their deployment in the total synthesis
of natural products.
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