This book discusses the influence of the brain microcirculation on
the development of the pathological changes in Creutzfeldt-Jakob
disease (CJD). Also, the ultrastructural characterisation of
pathological aspects of cutaneous microcirculation in patients with
vascular cognitive impairments are reviewed. Finally, Non-invasive
diagnostic techniques, such as capillaroscopy and nailfold
capillaroscopy are examined. The former technique is fundamental in
viewing peripheral circulation and in studying microangiopathies.
The non-invasive method of videocapillaroscopy is also discussed in
relation to how it is used to observe the microcirculation
characteristics of the human oral mucosa. Also, Raynaud's
phenomenon, defined as bouts of reversible vasospastic ischemia
typically manifested upon exposure to the cold and/or in
association with emotional stress, are discussed in relation to
nailfold capillaroscopy.
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