Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Vimentin Concepts & Molecular Mechanisms (Hardcover)
Loot Price: R4,199
Discovery Miles 41 990
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Vimentin Concepts & Molecular Mechanisms (Hardcover)
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Intermediate filaments (IFs) are among the main cytoskeleton
components in most animal cells, being intermediate in diameter
between microtubules and actin filaments. Vimentin is one of the
large intermediate filaments (IFs) of eukaryotic cell's
cytoskeleton, being the major protein in mesenchymal cells and it
is frequently used as a developmental marker of cells and tissues.
It may be overexpressed in several cancers, such as lung, breast,
head and neck cancer, and sarcomas. Furthermore, it plays a main
role in rheumatoid arthritis and Crohn's disease. Thus, this book
will address main topics concerning promising therapeutic targets
for intestinal fibrosis, vimentin's potential role in epithelial
mesenchymal transition (EMT), the role of vimentin in rheumatoid
arthritis, vimentin mechanisms and endothelial migration, and EMT
and lung neoplasms. Also discussed are insights into the
proteomics' field. Many reputed experts worldwide contributed to
improvement of this book and it will give readers the state of art
regarding vimentin and novel approaches.
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