This book presents review articles in the study of genitourinary
medicine. Topics include basic research that investigates the
epigenetic mechanisms in urogenital cancers; the role of matrix
metalloproteinases in urothelial cancers; the role of toll-like
receptor genes in prostate cancers; recent emerging and novel
treatment modalities in advanced metastatic renal cell and bladder
carcinomas; novel mouse models for studying malformations in the
genitourinary tract; the role of tissue engineering in
genitourinary regenerative medicine; and clinical management of
patients with Vesicoureteric reflux. Apart from the very well-known
Wilms tumour (a form of paediatric hereditary kidney tumours),
little is known about paediatric nephritic syndrome and their
genetic causes and clinical manifestations. Hence, a special
chapter has been included that describes the recent genetic
technologies that identify gene mutations in patients with
paediatric nephritic syndrome. The specific gene mutations found in
these patients are often associated with rapid renal failures,
disease progression and poor survival outcome. Each of the articles
presented by authors from all over the world are renowned and
experts in their own field of research. The authors are based
either in research and/or a clinical setting and the articles are
only a summary of the view points of each of these authors.
General
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