This book provides clear guidance on how to achieve excellent functional results and avoid failures when performing cystectomy and orthotopic bladder substitution. The opening sections present helpful checklists relating to patient selection, preoperative management, the procedures themselves, intraoperative measures, postoperative management, and actions to be taken in the event of various symptoms and complications. The remainder of the book focuses in detail on a variety of specific points of interest such as how and why to attempt a nerve-sparing cystectomy, the role of pelvic lymph node dissection, physical and physiological considerations relevant to reservoir construction, metabolic consequences of the incorporation of bowel into the urinary tract, preservation of renal function, and quality of life issues. The information provided may not only be instrumental to urologists, but also to specialized health care professionals, as well as the concerned patients.

This eagerly awaited book offers a unique, comprehensive scientific study of the anatomy of the organ of female sexual pleasure. The authors use macroscopic and microscopic research to guide the reader from the glans, the visible part of the clitoris, where they explore the impressive sensory corpuscles, to the hidden roots of the bulbo-clitoral organ. They show its complexity, its exact location within the external genitalia and its intimate relationship with the urethro-vaginal pyramid. They also remind us that throughout history there has been a failure to understand this organ, and explain that this misunderstanding remains the cause of persistent excisions, criminal mutilating practices that have not yet been eradicated. Using extensive iconography, they demonstrate throughout this book that the bulbo-clitoral organ is an exceptional natural treasure that every woman possesses and that every man should know well.

Have you ever laughed so much you wet yourself - just a little bit? Or found yourself crossing your legs on the doorstep frantically searching for your keys? Do you get up at night to go to the toilet more than once? Then you need help from The Pelvic Floor Bible. Incontinence is both preventable and curable through pelvic floor exercises and rehabilitation but too many people assume nothing can be done, follow incorrect advice or are ashamed to seek help. We need to end the taboo now. Jane Simpson will show you how to incorporate pelvic floor exercises as part of your daily routine in order to prevent issues in later life and cure existing problems now. * Learn how to treat common problems such as stress incontinence, overactive bladder and prolapse *Get back into shape post-pregnancy *Enjoy a healthy sex life at every stage of your life "Thanks to Jane I am feeling physically better, stronger, and more confident.", Tonya, 29 "I hadn't quite appreciated how important my pelvic floor was until I hadn't got one! Jane helped me to restore and maintain my new floor and I would encourage everyone to exercise regularly and to follow Jane's advice" Louise, 53

Understanding prostate diseases without the proper and reliable guidance can be overwhelming because the internet, television and print media saturate us with information ranging from scientific studies across the world to inspiring stories from cancer survivors to many myths and rumors. How do we interpret all that information? This book intends to help patients and their families to know and understand their diagnosis. Once this has been established, the reader can confidently determine the best choice of treatment, resting assured that the guidance in this book adheres to current international medical standards and has been influenced by the authors' many years of professional experiences. The editors aim to transmit, in a simple and precise manner, only relevant and necessary information to help patients and families that have been diagnosed with prostate diseases.

This book discusses the latest findings on the pathogenesis and treatment of IgA nephropathy. It particularly focuses on recently recognized initiation and progression factors and the varying treatment strategies in different regions, such as Asia, Europe, and the United States. More than 40 years have passed since Dr. Jean Berger first described primary IgA nephropathy ("Nephropathy with mesangial IgA-IgG deposits") as a new disease entity. Immunohistopathologically, IgA nephropathy is characterized by the granular deposition of IgA (IgA1) and C3 in the glomerular mesangial areas with mesangial cell proliferation and the expansion of mesangial matrices. It is clear that IgA nephropathy is one of the most common types of chronic glomerulonephritis in the world. This disease may lead to end-stage kidney disease, with its enormous economic impact on healthcare everywhere. Efforts by many investigators around the world have gradually clarified various aspects of the pathogenesis and treatment of IgA nephropathy. However, there are many controversial strategies for the treatment of patients with IgA nephropathy throughout the world, as there are several limitations for treatment in each country. This volume provides nephrologists everywhere with an overview and comparison of both global and regional findings in basic and clinical fields in IgA nephropathy. It covers genetic variation, aberrant IgA1 production, and classification etiology, guidelines, and treatment goals, with all chapters written by top international researchers.

This title offers full-color, step-by-step guidance on how to perform the most popular procedures in cosmetic surgery. Using more than 250 full-color illustrations and photos, and clear, concise text, "Cosmetic Surgery" teaches you how to perform the latest and most in-demand surgical and non-surgical procedures in aesthetic plastic surgery. Each chapter includes patient selection and preparation, technique, complications, outcomes assessment, and references, and many illustrations that have been prepared specifically for this book. It features a consistent, easy-to-navigate approach that facilitates quick learning. It includes more than 250 full-color illustrations that clarify each step of every procedure. It also features expert authorship by experienced plastic surgeons. It offers comprehensive coverage of: facial surgeries including facelift, brow lift, blepharoplasty, otoplasty, rhinoplasty, and chin implants; breast surgery, body contouring, and bariatric plastic surgery including breast augmentation, breast reduction, abdominoplasty, brachioplasty, and liposuction; non-surgical options including Botox, injectable fillers, chemical peel, dermabrasion, and laser surgery; and, other considerations such as new developments in cosmetic surgery, the business of cosmetic surgery, and the public's view of cosmetic surgery.

This unique textbook - the first of its kind - presents a thoughtful and comprehensive discussion of the significance of varicocele and its impact on male fertility. This hot topic is covered from a multitude of angles in seven thematic sections: origin and pathophysiology, clinical evaluation, medical and surgical therapy, controversies, pro and con debates, and clinical case scenarios. The scope of varicocele includes basic and transitional research, genetics, diagnostic testing with conventional and advanced molecular biology approaches, hormonal control, interventional therapy and assisted reproductive technology (ART). Repair of varicocele, which can be carried out by various methods, not only alleviates oxidative stress-associated infertility but also prevents and protects against the progressive character of varicocele and its consequent upregulations of systemic oxidative stress. Even with the advances in the understanding of this intriguing disease and consensus on some areas such as diagnosis and pathophysiology, substantial controversy still exists, in particular concerning the benefits of treatment and to whom treatment should be offered. Additional chapters discuss, in depth, such controversies surrounding the role of varicocele in male infertility and present clinical case scenarios dealing with management of subclinical and clinical varicocele. A series of editorial comments is provided by the editors at the end of selected chapters, containing an objective and concise summary of the information from each chapter. In addition, chapters open up with key points for quick references and conclude with multiple choice questions and answers for immediate review and retention of the rich content. Generously illustrated, Varicocele and Male Infertility: A Complete Guide represents an invaluable tool for medical students in reproductive medicine as well as researchers and clinicians working in the field of infertility (e.g., urologists, gynecologists, reproductive endocrinologists, and embryologists) and is comprised of chapters written by leading and internationally recognized clinicians and scientists with expertise in varicocele, skillfully edited by leaders in the field.

This concise, practical guide is structured to reflect the thought process of the practising pathologist. A key feature is the use of algorithms to aid in reaching the correct diagnosis, for both common and complex bladder tumors and tumor-like lesions. Its coverage of diagnostic criteria is in keeping with international standards and best practice, and the practical layout provides quick access to relevant information, integrating conventional histology, immunohistochemical markers and key clinical knowledge. Topics covered include the full spectrum of pathologic conditions that afflict the bladder and urothelium, as well as the pathology of the renal pelvis, ureter and the urethra. Accompanied by numerous images, this is an essential guide for trainee and practising surgical pathologists, urologists and oncologists.

Urologists interested in prosthesis surgery currently offer a range of procedures eg slings for incontinence in both men and women, and is also within the remit of those undertaking AUS (artificial urinary sphincter) implantation, and likewise andrological surgeons undertaking penile prosthesis also offer AUS. There are a number of procedures which are common to all urologists with a general urology practice eg ureteric stents and testicular implants. However, the purpose of this book is to cover this area of urological surgery and provide a reference book for those interested in expanding their practice.

Take Control of Your Interstitial Cystitis Treatment with this Comprehensive Guide! Interstitial cystitis (IC), also called painful bladder syndrome, is a complex bladder pain condition that can be confusing, frustrating, and debilitating. Successful treatment requires a multidisciplinary approach that often features a combination of medication, physical therapy, dietary and lifestyle changes, alternative medicine, and more. The Interstitial Cystitis Solution has all the information you need, all in one place. It provides scientific reviews and evaluations of potential treatments, along with a helpful treatment plan tailored to your specific symptoms and lifestyle. The information is presented in an accessible way, with real-life examples from the author, who has treated hundreds of patients who have found relief from their symptoms with the holistic treatment plan outlined in this book. This comprehensive guide allows you to take control of your healing and will restore sanity to the insane world of conflicting diagnoses, treatments, and advice.

This book provides comprehensive coverage of the current and emerging management of prostatitis, from diagnosis to therapy. It addresses all clinical aspects of the prostatitis syndrome and equips the reader with all the information needed to offer a tailored therapy. Furthermore, clinical implications of the disease are analyzed and discussed, with particular attention to andrological complications (infertility) and the possible link between prostatitis and prostate cancer. Special consideration is also given to contemporary aspects of prostatitis management relating to antibiotic stewardship and elevated PSA, bearing in mind that thoughtless treatment of prostatitis represents malpractice and sometimes even a forensic issue. The final chapter comprising questions and answers will be valuable for quick consultation in everyday clinical practice. This book will be a truly practical guide for physicians involved in the diagnostic work-up and treatment of patients suspected of having prostatitis and will also serve as a ready source of information for all physicians who occasionally see prostatitis patients.

This book focuses on a novel series of minimally invasive surgeries performed without gas insufflation and through a single port using the RoboSurgeon system. The concept of RoboSurgeon surgery involves a degree of "robotization" of the operator and participants. The operator, wearing a head-mounted display, uses robot-like handheld instruments. The endoscope is controlled by the movement of the operator's head using a gyro-sensor system. All participants wearing head-mounted displays can see the same images as the operator does. Although this surgery is mainly intended for urological cancers, it may also be applicable for various operations concerning other urological diseases, as well as for the treatment of diseases in different medical fields. The system has the potential to become the new standard in robotic surgery. This solution may be a boon to many patients around the world, especially in the aging societies many countries are now facing.

This revised and updated second edition provides a comprehensive account of the human male gamete. Detailed overviews of human sperm production, maturation, and function - and how these processes affect and influence fertility, infertility, and assisted reproduction - are given. A wide range of new developments including proteomics, spermatogenesis, sperm-specific WW domain-binding proteins, Ca2+ signalling, DNA packaging, epididymis are explored, whilst a new chapter presents information gained from mouse genetics, highlighting how it informs male fertility research. The impact of environmental factors during pre-pubertal and pubertal stages of life is also investigated. Featuring engaging prose with chapters organized topographically, The Sperm Cell remains an essential resource for andrologists, clinical scientists, and laboratory personnel.

This booklet is for those suffering from exertion or 'stress' incontinence. It describes a new approach based on a planned series of exercises aimed at restoring the bladder. The anatomical causes of this type of incontinence are clearly explained and illustrated. There is no substitute for the self-discipline of exercises, but the book also deals with two other important points: correct breathing and balanced diet which will not lead to constipation or to being overweight. There is also a section on preparations for counteracting the incontinence that may result from pelvic surgery. Doctors and physiotherapists will be able to recommend this booklet to their patients.

This new volume fills the gap in the literature as it will guide urologists and pathologists in the proper utilization of a variety of laboratory methods that are currently available to determine the presence, persistence or progression of tumors of the lower urinary tract. The volume emphasizes cytology of the urinary tract which is preferred over other methods (i.e. biochemical, immunological and cytogenetic) for its accuracy, especially for the important high grade tumors. This volume will appeal to urologists as well as pathologists, cytopathologists and related professions. The illustrations, nearly all in color, stress the key points of the text and enhance basic understanding of urothelial and other tumors of the urinary tract.

This text focuses exclusively on the anatomical, physiological, pathological, and technical aspects of post robotic prostatectomy urinary continence and erectile function. It provides a comprehensive insight into the mechanisms responsible for maintaining urinary continence and erectile function and elucidates the key concepts and techniques utilized to achieve early return of urinary continence and erectile function after robotic radical prostatectomy. Surgical techniques with pre and post-operative interventions known to improve urinary and sexual function are integrated. A step- by- step "evidence- based" description of surgical techniques utilized in achieving the goals of urinary continence and erectile function are the hallmark of this book. A state-of-the art exhaustive review of "tips and tricks" utilized to achieve the trifecta of cancer control, urinary continence and erectile function in different clinical scenarios like large prostates, post TURP, and salvage robotic prostatectomies complete the text and make it the most exclusive resource available for both the expert and the novice robotic surgeon looking to improve patient outcomes after robotic radical prostatectomy. All chapters are written by world renowned experts in their fields and include extensive illustrations and videos to make this the most interactive and visually appealing text available.

UTIs affect a large proportion of the world population and account for significant morbidity and high medical costs. This comprehensive and authoritative volume on infections of the urinary tract covers the range of the field, from molecular pathogenesis to the host response to clinical diagnosis and management.

An updated and revised resource to evidence-based urology information and a guide for clinical practice The revised and updated second edition of Evidence-Based Urology offers the most current information on the suitability of both medical and surgical treatment options for a broad spectrum of urological conditions based on the best evidence available. The text covers each of the main urologic areas in specific sections such as general urology, oncology, female urology, trauma/reconstruction, pediatric urology, etc. All the evidence presented is rated for quality using the respected GRADE framework. Throughout the text, the authors highlight the most patient-important, clinical questions likely to be encountered by urologists in day-to-day practice. A key title in the "Evidence-Based" series, this revised and expanded edition of Evidence-Based Urology contains new chapters on a variety of topics including: quality improvement, seminoma, nonseminomatous germ cell tumor, penile cancer, medical prophylaxis, vesicoureteral reflux disease, cryptorchidism, prenatal hydronephrosis, and myelodysplasia. This updated resource: Offers a guide that centers on 100% evidence approach to medical and surgical approaches Provides practical recommendations for the care of individual patients Includes nine new chapters on the most recently trending topics Contains information for effective patient management regimes that are supported by evidence Puts the focus on the most important patient and clinical questions that are commonly encountered in day-to-day practice Written for urologists of all levels of practice, Evidence-Based Urology offers an invaluable treasure-trove of evidence-based information that is distilled into guidance for clinical practice.

Today, the arsenal of high-precision or targeted radiotherapy includes a variety of techniques and approaches that, like the pieces of a puzzle, need to be put together to provide the prostate cancer patient with high-level optimized radiation treatment. This book examines in detail the role of these innovative radiation techniques in the management of prostate cancer. In addition, a variety of current controversies regarding treatment are carefully explored, including whether prophylactic treatment of the pelvic lymphatics is essential, the magnitude of the effect of dose escalation, whether a benefit accrues from hypofractionation, and what evidence exists for the superiority of protons or heavy ions. "Radiotherapy in Prostate Cancer: Innovative Techniques and Current Controversies" is intended for both radiation oncologists and urologists with an interest in the up-to-date capabilities of modern radiation oncology for the treatment of prostate cancer.

Image-Guided Prostate Cancer Treatments is a comprehensive reference and practical guide on the technology and application of ultrasound and MRI in the male pelvis, with special attention to the prostate. The book is organized into three main sections, the first of which is devoted to general aspects of imaging and image-guided treatments.The second section provides a systematic overview of the application of ultrasound and MRI to the diagnosis and treatment of diseases of the lower urinary tract. Performance of the ultrasound and MRI studies is explained, and the normal and abnormal pathological anatomy is reviewed. Correlation with the ultrasound in the same plane is provided to assist in understanding the MRI sequences. Biopsy and interventional procedures, ultrasound-MRI fusion techniques, and image-guided therapies, including focused ultrasound, photodynamic therapy, microwave and laser ablation, are all fully covered. The third section focuses on securing treatment effectiveness and the use of follow-up imaging to ensure therapeutic success and detect tumor recurrence at an early stage, which is vital given that prompt focal treatment of recurrence is very successful. Here, particular attention is paid to the role of Doppler ultrasound and DCE-MRI technologies. This book, containing a wealth of high-quality illustrations based on high-end equipment, will acquaint beginners with the basics of prostate ultrasound and MRI, while more advanced practitioners will learn new skills, means of avoiding pitfalls, and ways of effectively relating the imaging and image-guided treatments to the clinical situation. The information provided will permit a tailored approach in dealing with specific pathologic issues."

Robotic Surgery of the Bladder is a dedicated resource to understanding and mastering the concepts and practical aspects of robotic bladder surgery. The volume provides an introduction to urologists interested in initiating robotic radical cystectomy by providing them background, concepts, steps, and tools and tricks to introduce robotic radical cystectomy into their clinical practice, all in a safe, stepwise, and organized manner. For the more experienced robotic surgeon, the text serves as a resource for more advanced applications and techniques. The volume is also accompanied by many still images and a DVD of video clips. Written by experts in the field, Robotic Surgery of the Bladder is a comprehensive resource that maintains the time-tested oncologic principles of bladder cancer surgery, while introducing the advantages that exist with robotic-assisted approaches.

Functional urology is that part of urological practice which deals with functional disorders of the lower urinary tract. Among the diseases that cause functional disorders are spina bifida, spinal cord injury, pelvic organ prolapse, and urethral strictures. This book on practical functional urology will help urologists, urogynecologists, and others to diagnose and treat these functional disorders. The theoretical background and scientific basis are summarized, but the emphasis is very much on clinical practice. Diagnosis and treatment are presented for a variety of conditions, including overactive bladder, detrusor underactivity, painful bladder syndrome/interstitial cystitis, prostatitis, stress urinary incontinence, pelvic organ prolapse, urinary tract infections, and urethral disorders. The content is based on the EAU guidelines, and for each disorder, helpful tips and tricks are highlighted.

Urology is a speciality that notoriously receives little attention in medical school, yet it makes up a sizeable portion of the workload in emergency departments and also in primary care. Urological emergencies can often be managed simply but require the appropriate knowledge and skills. Emergency urology is often covered very superficially alongside general surgery or in excessive detail within voluminous urology textbooks. This book is different: it will consist of concise, well-structured chapters, with an accessible and easily digestible style. The content will be clinically-based and will include a number of clinical photographs and radiological investigations. This book will appeal to all doctors, including those rotating through surgical and emergency medicine specialities, and those clinicians approaching professional examinations worldwide. Medial students on urology or emergency medicine placements, who are studying for their exams will also find it invaluable. In addition, primary care doctors, speciality nurses in urology and nurses in emergency department may also appreciate the clinically relevant content of the book. The authors are all dedicated to education and teaching, and have published extensively. In addition, they run a successful emergency urology course in Cambridge, popular with clinicians and senior students alike.

This book systematically reviews and discusses recent studies and articles on the immunology of female genital tract tissue. The scope is broad, encompassing innate immune responses, adaptive (humoral and cell-mediated) immunity, the immunology of menstruation, the immunology of viral and bacterial infections, the immunology of normal and abnormal pregnancy, and immunological infertility. Throughout, tables and illustrations are judiciously used to facilitate understanding. Immunology of the Female Genital Tract will serve as an invaluable source of up-to-date information for all with an interest in this subject.