The past decade has been marked by the acceleration of our understanding of the molecular biology of cancer. Simultaneously, there have been increasing exigencies to diagnose, treat and follow cancer patients more economically. Biomarkers represent the marriage of science and economics. Biomarkers offer the potential to increase the precision of diagnosis, prognosis, and surveillance of urological malignancies. This issue presents the cutting-edge advances of biomarker technology to urologic oncology.

This book aims to enable healthcare workers in creating online learning tools for their specific surgical procedures. Providing an e-learning base by which healthcare workers can create customized procedural training materials, this book empowers practitioners to instruct their staff both within and across specific institutions or surgical areas. Supplying surgical leads with the tools required to inform their team members of what they need to know, what they will be expected to do, and when they will be expected to do it, the methods put forth in this book assist healthcare teams in working more closely and efficiently. Using the techniques this text describes, staff surgeons will be able to streamline their surgeries and support each of their staff members to perform their best. Focused on pediatric urological healthcare workers, each chapter demonstrates real-world applications for the development of codified training procedures. Supplemented with downloadable files for customization, the principles presented in this book apply to diverse specialties including but not limited to urology, orthopedics, obstetrics, and ophthalmology. A Guide to Make Applications for Holistic Surgical Practice: The Computer Enhanced Visual Learning (CEVL) Manual emphasizes practical approaches to the development of training methods for the codification of procedure performance within or across specific institutions or surgical leads.

This book is an academic and practical guide to the diagnostic methods and management strategies for both common and rare scrotal diseases. Chapters focus on the normal anthropometric measures of the scrotum as a unique organ and the latest relevant advancements in the field. Techniques including scrotal reconstruction for congenital abnormalities, trauma, and cancer-related extirpation are all covered. Critical tools and methods related to aesthetics are also detailed. Emphasis is also placed on identifying common pitfalls and how to avoid them, ensuring that the reader is fully equipped to deal with a range of scenarios. Normal and Abnormal Scrotum describes how to approach diagnosing and managing the entire range of scrotal diseases, making it essential for all general practitioners, pediatricians, urologists, and pediatric and aesthetic surgeons who encounter these patients in their day-to-day practice.

Prostate Cancer, Science and Clinical Practice, Second Edition, continues to be an important translational reference that bridges the gap between science and clinical medicine. It reviews the biological processes that can be implicated in the disease, reviews current treatments, highlights the pitfalls where relevant, and examines the scientific developments that might result in future treatments. Key chapters from the previous edition have been updated, and a plethora of new chapters describe new concepts of prostate cancer biology and newly developed therapeutics. Each chapter has been written by internationally recognized specialists on prostate cancer epidemiology, genetic susceptibility, cancer metastases, prostate physiology, proteomics, new therapeutics, and clinical trials.

This book provides a practical guide to surgical endourology. Evidence-based chapters give expert opinion on complex cases, best practice techniques, and treating complications. The book covers a broad range of topics required within urological treatment including basic science, imaging in endourology, the use of technological devices, therapeutics for endourology, the treatment of high risk patients, stone disease management, pelvic kidneys, and dialysis. Surgical Strategies in Endourology aims to give the reader guidance in treating patients with endourological conditions and is relevant to both practising and trainee urologists.

The Guest Editors have assembled top key opinion leaders to provide current reviews on the multidisciplinary approach to the management of high-grade bladder cancer. Articles are devoted to fluorescence cystoscopy, confocal laser endomicroscopy, narrow band imaging; Novel therapeutic approaches for recurrent nonmuscle invasive bladder cancer; Trimodality therapy in bladder cancer; the data and the reality of perioperative chemotherapy in muscle invasive bladder cancer; radical transurethral resection alone, robotic or partial cystectomy or extended lymphadenectomy: Neoadjuvant paradigm for drug development in muscle invasive bladder cancer; Novel biomarkers to predict response and prognosis in localized bladder cancer; Immunotherapy in Advanced/Metastatic Urothelial Cancer ; and Adjuvant Chemotherapy in High Grade Upper Tract Urothelial Cancer.

This book provides a practical guide to the use of the latest applicable surgical procedures and present novel pathways. It details how to utilize a range of techniques including three-dimensional (3D) laparoscopy and those that require robotic assistance. Guidance is also contained on innovative tools including confocal laser endomicroscopy along with the application of biomaterials, artificial intelligence and other exponential technologies, enabling the reader to systematically develop a thorough understanding of these methodologies. Urologic Surgery in the Digital Era: Next Generation Surgery and Novel Pathways systematically reviews the application of the latest surgical techniques and potential future developments in urology. Therefore, it is a critical resource for all practicing and trainee urological surgeons.

Clinics in Developmental Medicine No. 170

Elimination disorders (nocturnal enuresis, urinary incontinence and encopresis) are among the most common disorders of childhood. Some disorders are primarily genetically determined, in others environmental factors predominate. Also, the rate of comorbid behavioural disturbances differs greatly from one syndrome to another. Because of this variety and heterogeneity, each disorder requires specific approaches in assessment and treatment. This book provides an evidence-based overview of functional elimination disorders. It draws on the standardisation and terminology suggested by the International Children's Continence Society. Short case vignettes, photos and line drawings, as well as questionnaires and charts are provided. To enable a quick orientation for clinical purposes, each chapter is followed by summaries, guidelines and diagrams. It will be of interest to all professionals working in the field.

Urologists were early adaptors of robotic assisted laparoscopy, and pediatric urology similarly led in incorporating the technology into the surgical armamentarium for treating even the smallest infants. And it is in that tradition that this issue of Urologic Clinics of North America surveys the journey from the earliest pure laparoscopic procedures to the most advanced reconstruction possible today due to evolutions in technology. The issue begins with the procedure that arguably popularized the laparoscopic approach in pediatric urology-the laparoscopic orchiopexy, then posit the continued relevance of pure laparoscopy in the robotic era, before finally surveying contemporary advances in robotic-assisted pediatric urologic surgery. The issue is of relevance not only tor the novice contemplating a transition to laparoscopy or robotics but also for the seasoned minimally invasive surgeon seeking to enhance skills and augment his or her practice.

Robotic-assisted laparoscopic urologic surgery is a major evolution in the field and has now become a major subspecialty. This issue of Urologic Clinics of North America aims to provide comprehensive, state-of-the-art information about the recent developments in the areas of Uro-Oncology, Reconstructive Urology, and Female Urology. Topics such as issue of training, evidence-based practice, the economics of robotic surgery, and the impact on public and global health are also covered.The contributors are truly pioneers and the best experts in the field.

The Year Book of Urology brings you abstracts of the articles that reported the year's breakthrough developments in urology, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed! The Year Book of Urology is published annually in December.

Kidney anomalies are the most frequent abnormality detected on prenatal ultrasound. Some are inconsequential and others are life-threatening. All must be addressed by neonatologists. This edition of Pediatric Clinics of Perinatology covers these anomalies. In addition, it addresses a variety of other nephrology and urology issues that neonatologists confront. Some are rare and the chapter may then serve as an important resource. Others are common, and thus will provide updated information on diagnosis and management.

This issue of the Urologic Clinics will focus on urodynamic testing in men, women and special situations. Appropriate urodynamic testing options including video urodynamics, pressure flow studies, and neurogenic voiding discussion will be discussed. Dr. Nitti and Dr. Brucker have assembled well known experts in their fields to provide current clinical information for urodynamic evaluation, diagnosis, and treatment.

This issue of Ultrasound Clinics features a review of genitourinary topics and includes the following articles: Characterization of Renal Masses by Ultrasound; Renal Malignant Masses as Characterized by Ultrasound Contrast; US Elastography of Kidney; Prostate Biopsies and Controversies; Post-vasectomy Complications; Acute Scrotum; Testicular trauma- Role of Sonography; Testicular Elastography; Contrast Enhance Ultrasound of the testes; and Vascular Complications of Renal Transplant.

PSA screening remains highly controversial due to several important disadvantages. More PSA is produced with prostatic enlargement and in other benign conditions such as urinary tract infections. False positive tests can then lead to unnecessary diagnostic workup with invasive prostate biopsy. Another major problem with screening programs in general is overdiagnosis of cancers that would not have caused harm during the patient's lifetime. For example, many prostate cancers have a relatively indolent behavior so may not require diagnosis or treatment in a patient with limited life expectancy. All forms of prostate cancer treatment have potential urinary and sexual side effects, so reducing overdiagnosis and overtreatment are critical public health issues. Because screening has many proven benefits but also significant harms, there are widely disparate guidelines on prostate cancer screening from major organizations worldwide. This issue of the Urologic Clinics will provide insights into the many different prostate cancer guidelines and related policy issues.

The Year Book of Urology brings you abstracts of the articles that reported the year's breakthrough developments in urology, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed! The Year Book of Urology is published annually in December.

This issue of the Urologic Clinics covers stricture, renal injuries, priapism, penile fractures, and bladder injuries. An article covering necessary plastic surgery principles for the urologist is also included. Dr. Allen Morey serves as Guest Editor of this issue on urologic trauma and reconstruction. Dr. Morey has extensive clinical experience in reconstructive urology with emphasis in urethral stricture disease, and urologic trauma.

This issue of Hematology/Oncology Clinics is focused on Prostate Cancer and highlights topics such as: Prevention, Early Detection, Biomarkers, Risk stratification, Imaging in Prostate Cancer, Adjuvant hormonal therapy, Management of patient with biochemical relapse, Management of patient with newly metastatic disease, and Bone Health Management.

Surgery for Urinary Incontinence, by Drs. Roger Dmochowski, Mickey M. Karram, and W. Stuart Reynolds, is the ideal way to sharpen your skills in the diagnosis and management of this condition. In this volume in the Female Pelvic Surgery Video Atlas Series, edited by Mickey Karram, MD, detailed discussions and illustrations, case studies, and video footage clarify how to most effectively select and perform a variety of procedures and manage complications. Case-based presentations and videos, narrated by the authors, take you step by step through a variety of procedures, including synthetic biologic slings, suspensions, botox injections, the use of neuromodulation devices, and more Heavily illustrated, quick-reference chapters Discuss all of the possible diagnoses and management options for urinary incontinence problems Case studies describe the clinical history surrounding each case featured in the videos, and demonstrate how to manage a variety of recurrent cases as well as how to avoid and manage complications Online access at; www.expertconsult.com places the full text, videos, and more at your fingertips on any computer or mobile device

Castrate Resistant Prostate Cancer is advanced disease that has stopped responding to hormone therapy. This issue of the Urologic Clinics focuses on the various forms of therapy including immunotherapy, first line chemotherapy, and novel targeted agents. Articles on defining the diseae and palliative care are also included.

The Year Book of Urology brings you abstracts of the articles that reported the year's breakthrough developments in urology, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed The Year Book of Urology is published annually in December.

This issue of the Urologic Clinics is unique in that it examines the Controversies in Female Pelvic Reconstruction from both the urology and urogynecology standpoint. Areas of controversy regarding evaluation and therapy for a number of conditions unique to women's health are examined. Topics covered include urethral bulking, robotic/laparoscopic prolapse repair, management of bladder pain syndromes, and urodynamics.

The articles in this issue update important topics in pediatric urology, but also address some of the more controversial clinical topics. Those topics included in this issue are Prenatal Ultrasound and Urological Anomalies, Spina Bifida and Neurogenic Bladder, Inguinal and Genital Anomalies, Voiding Dysfunction, Vesicoureteral Reflux, Hydronephrosis, Urolithiasis in Children, Urinary Tract Infection (UTI) work up, Advances in Surgical Pediatric Urological Armamentarium, Pediatric Urologic Oncology, Pediatric Urological Emergencies, and Circumcision Controversies.

This book is exclusively devoted to the often-challenging diagnosis, management and treatment of patients with non-neurogenic bladder dysfunction. A unique team of experts in the field report on the state of the art and the latest trends concerning overactive and underactive bladder dysfunctions, while also discussing detrusor overactivity impaired contractility. Given its scope, the book will benefit all urologists, and offers a valuable tool for professionals and physicians who care and deal with patients with non-neurogenic bladder dysfunctions.