Male Infertility: Sperm Diagnosis, Management and Delivery provides a comprehensive understanding of various aspects of male infertility and its treatment. The book opens with an introduction to basic anatomy and physiology and includes subsequent chapters on the causes and effects of poor semen quality, guidance on how to perform semen analysis, cryo-banking and oncology, ethical and regulatory requirements of using male gametes for fertility treatment, and future technologies. Richly illustrated throughout, this is a key resource for all andrologists and clinicians specialising in reproductive medicine, gynaecology, oncology, infertility and embryology. Covers all aspects of sperm diagnosis, management and delivery Written and edited by leading experts in the field Defines standards of practice and provides methodologies and protocols for best practice

Expert Opinions in Female Pelvic Medicine and Reconstructive Surgery covers a range of female urologic disorders, using a case-based approach to provide timely guidance on diagnosis and management. Forty cases of varying complexity are introduced by the editors and illustrated where appropriate by clinical findings. One or two expert reviewers then present their protocols for the management of each case, and their projected prognosis. Sometimes these views may diverge, as they do in practice. In all cases therefore, the editors add a final commentary to those of the expert reviewers, to summarise current management protocols and guide the reader towards an optimum treatment plan. Presents 40 urological cases Expert reviewers present their protocols for each case and the editors summarise the current management procedures Clinical findings are presented with images and urological graphs Provides an expert guide to the diagnosis and management of female urologic disorders

In consultation with Consulting Editor, Dr. Samir Taneja, Guest Editors Dr. Brian Matlaga and Dr. Ojas Shah have put together a timely look at Emerging Technologies in Renal Stone Management. The issue focuses on techniques and newer generation of lasers, fiberoptics, and imaging techniques. Clinical review articles are specifically devoted to the following: Next Generation Reusable Ureteroscopes: Fiberoptic and Digital; Single-Use Ureteroscopes; Disposable Stone Retrieval Devices; New Generation Laser Fibers; Emerging Laser Techniques for Stone Management; Ultrasonic and Pneumatic Lithotripters; Emerging technologies in lithotripsy; New technologies to aid in percutaneous access; Innovations in Ureteral Stent Technology; New imaging techniques in the Management of Stone Disease; Radiation Mitigation Techniques; Ultrasound Technology in the Management of Stone Disease; Emerging Mobile Platforms to Aid in Stone Management; and Assessing Cost-Effectiveness of New Technologies in Stone Management. Readers will come away with the latest information they need to optimize treatment and management outcomes in the patient with stone disease.

This book offers a practical and modern update on radioisotope therapy. Clinically oriented, it provides a thorough guide to patient management, with the latest indications and procedures for the current radioisotopic treatments. It addresses the clinical problems associated with each respective pathology, discussing the management of patients (diagnosis and non-radioisotope therapy), the radiopharmaceuticals available today, and the current radioisotopic procedures. Wherever possible, information on dosimetry is included at the end of each topic, together with a list of and comments on the most recent guidelines with their recommendations for radiometabolic therapy. The book is divided into six main sections: thyroid diseases, hepatic tumors (HCC and hepatic metastases), bone metastases from prostate cancer, lymphomas, and neuroendocrine tumors. The last section is dedicated to new perspectives of radioisotope treatment. Based on contributions from of a multidisciplinary team of specialists: oncologists, surgeons, endocrinologists, hematologists, urologists, radiopharmacists and nuclear medicine physicians, it provides a comprehensive analysis of the position of radioisotope treatments among the various therapeutic options. Readers interested in targeted therapy, radiometabolic therapy, radioimmunotherapy and radiometabolic imaging will find this book both informative and insightful.

This reference brings together all aspects of renal cell carcinoma, and provides a basis for understanding the disease's origin, progression and responses to immunotherapy.;Examining the current status of cytokine, cell-based and chemotherapeutic methods of treatment, this book: discusses the clinical presentation of advanced renal carcinoma and its therapeutic challenges; reviews prognostic factors and the management of renal cell carcinoma occurring with von Hippel-Landau syndrome; summarizes efforts to identify the tumour suppressor gene deleted from chromosome 3 in most renal cell carcinomas; explicates the role of oncogenes in the progression of renal cell cancer and the molecular correlates of responses to interferon-alpha treatment; details the latest laboratory efforts to establish gene therapy for tumour treatment by transfection of cytokine genes in murine model systems; focuses on biologic response modifier therapy in humans, including cell-mediated immune responses and adoptive immunotherapy; presents preclinical and clinical studies of interleukin-2 alone, in combination with othe cytokines, and with chemothrapeutic agents; and addresses studies on the tumour necrosis factor and low- and high-dose interferon-alpha.

Sexually transmitted infections remain a global health concern with the World Health Organization reporting over 340 million new cases of bacterial and protozoal STI every year, worldwide. They are frequently associated with a significant degree of medical and psychological morbidity. This full-colour pictorial guide is a unique, single volume compilation of common diseases in genito-urinary medicine. It covers a wide range of ailments from sexually transmitted infections to dermatological conditions affecting the genito-urinary system. Each high-quality image is accompanied by a clear, concise description to aid diagnosis. As well as providing a diagnostic tutorial for trainees in genito-urinary medicine, this book is a reference for any healthcare professional encountering these diseases. Candidates for the Diploma of Genito-urianry Medicine and the Knowledge Based Assessment in Genito-Urinary Medicine will find this visual compendium invaluable.

Extensively revised to bring you up to date with new pathologic entities, new treatment methods, and much more, Biopsy Interpretation of the Bladder, Third Edition is a highly practical guide to effective diagnostic biopsy of the urothelial tract. Presented in a reader-friendly format, it helps you accurately identify all lesions, tumors, and tumor-like lesions for the bladder - from normal anatomy and histology to a wide range of both common and unusual findings In addition, exclusive online content includes the fully searchable text, an image bank with 1,500 additional e-figures, and an interactive quiz bank ideal for board exam preparation. NEW to the Third Edition: The latest World Health Organization and International Society of Urologic Pathology classifications incorporated throughout. A completely revised chapter on urine cytology, with many new images. New sections on how to handle papillary tumors with borderline features between low-grade and high-grade carcinoma, as well as tumors with mixed low-grade and high-grade features. New information on how to use immunohistochemistry in the classification of precursor lesions, as well as how best to apply IHC panels to establish site of origin. Expanded information on the morphologic spectrum of glandular lesions. Updated sections on both schistosomiasis and non-schistosomiasis associated squamous cell carcinoma, including their relation to HPV, IHC, and prognosis. A significantly revised chapter on secondary tumors, including sections on distinguishing UC and bladder adenocarcinoma from prostate adenocarcinoma, colorectal adenocarcinoma, and uterine cervical carcinoma. Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like: Complete content with enhanced navigation Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web Cross-linked pages, references, and more for easy navigation Highlighting tool for easier reference of key content throughout the text Ability to take and share notes with friends and colleagues Quick reference tabbing to save your favorite content for future use

This book is designed to meet the needs of nurse practitioners, advanced practice nurses and also physician assistants, working in urology. The full range of domains of practice is covered, including assessment and diagnosis, clinical management, nurse practitioner and patient relationships, consultation, health promotion and disease prevention, and practice management and research. Some background knowledge is assumed regarding the normal anatomy and physiology of the genitourinary system and the pathophysiology underlying specific urologic health-related problems. The Nurse Practitioner in Urology will be invaluable in ensuring that the nurse practitioner is able to maintain exemplary management of patients with acute and chronic urologic conditions in a wide variety of settings, including independent practices, hospitals, and academic urologic practices. It explains fully the role of the nurse practitioner as a skilled clinician in urology, blending nursing and medical management and capable of managing many chronic nonoperative urologic conditions while recognizing those conditions which may benefit from surgical management. As populations continue to age worldwide, there is no doubt that the provision of advanced urologic care by nurse practitioners is an area that will continue to expand, benefiting from additional training and expertise.

Urolithiasis, or stone disease occurs in 7% of women and 12% of men at some point, and these statistics are rising. Furthermore, for those who form a stone, the likelihood of a recurrence is nearly 50% within 5 years of initial diagnosis. Therefore, the need for effective, minimally invasive alternatives for stone eradication and prevention is critical. Because stone disease comprises a large part of any urologist s practice, a thorough knowledge of the pathogenesis and pathophysiology of stone disease is critical in order to understand and implement treatment strategies to prevent stone formation. Likewise, a working knowledge of the surgical treatments, instrumentation and outcomes is necessary to arm patients with sufficient information to make an informed decision and to provide the appropriate treatment modality for a given stone situation. In Urolithiasis: Medical and Surgical Management, the authors provide a complete guide to the management of stone disease from both a medical and surgical prospective. This book should be an invaluable resource for those who treat stone disease in any capacity, whether surgically or medically, acutely or long-term.

This book addresses various aspects of testicular autoimmunity. It has long been suspected that testicular autoimmunity could be one of the causes of idiopathic male infertility. However, it is very difficult to estimate the incidence of testicular autoimmunity in men, as most male patients first realize they are infertile when they start trying to conceive a child, and there is a possibility that their testes may already exhibit the end stage of testicular autoimmunity, in which lymphocytic inflammation and immunoglobulin deposition in their testes subsided long ago and only the spermatogenic disorder remains. Therefore, autopsy or biopsy for testicular tissues in men before the end stage of testicular autoimmunity and investigations using testicular autoimmunity model animals are needed to determine the epidemiology of testicular autoimmunity. Accordingly, the book discusses "the immunological fragility of testis" with regard to male infertility, reviewing autopsy data in men and presenting experimental data using murine models of autoimmune orchitis that has been induced by immunizing with viable syngeneic testicular germ cells alone. Testicular autoimmunity in animals is also discussed. In summary, the book provides a wealth of valuable information, not only for researchers who are interested in immunologic male infertility, but also for clinical professionals who treat these patients at hospitals.

This book is a comprehensive and current guide to the diagnosis and treatment of the entire spectrum of anorectal diseases. It focuses mainly on anorectal problems, as anorectal pathology is often more complex and challenging for surgeons than colonic diseases. The book covers anorectal anatomy, physiology, and embryology as a foundation to a detailed description of preoperative, intraoperative, and post-operative patient management. All surgical procedures are shown in step-by-step detail by leading surgeons and gastroenterologists. This book will be relevant to general, colon, and rectal surgeons in training and practice, gastroenterologists, and other practitioners with an interest in anorectal diseases.

This text provides a comprehensive review of pathophysiology, molecular and cell biology aspects of CRPC, discusses all major clinical trials that have led to approval of 6 new drugs since 2004, explores the role of bone preservation strategies, in depth analysis of combination and sequencing strategies, outlines upcoming novel drugs and trends in research, and stresses the role of palliative care in this incurable disease. Managing Metastatic Prostate Cancer in Your Urological Oncology Practice will serve as a very useful resource for physicians and researchers dealing with, and interested in prostate cancer. It provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and will include the most up to date scientific and clinical information.

This book provides current, comprehensive, and clear explanations of the physics behind medical and biomedical applications of shock waves. Extracorporeal shock wave lithotripsy is one of the greatest medical advances of our time, and its techniques and clinical devices are continuously evolving. Further research continues to improve the understanding of calculi fragmentation and tissue-damaging mechanisms. Shock waves are also used in orthopedics and traumatology. Possible applications in oncology, cardiology, dentistry, gene therapy, cell transfection, transformation of fungi and bacteria, as well as the inactivation of microorganisms are promising approaches for clinical treatment, industrial applications and research. Medical and Biomedical Applications of Shock Waves is useful as a guide for students, technicians and researchers working in universities and laboratories. Chemists, biologists, physicians and veterinarians, involved in research or clinical practice will find useful advice, but also engineers and physicists may benefit from the overview of current research endeavors and future directions. Furthermore, it may also serve to direct manufacturers towards the design of more efficient and safer clinical, industrial and laboratory equipment.