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Selected from the world's leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient. Prostate and Other Genitourinary Cancers: Cancer: Principles & Practice of Oncology, 10th Edition , offers a comprehensive and balanced view of this rapidly changing field, meeting the needs of oncology practitioners, fellows, and others who need an in-depth understanding of prostate and GU cancer. The print reference gives you the solid, dependable guidance you've come to expect from this outstanding title, and the Inkling version features new quarterly updates written by a team of experts selected by the authors. Key Features: Delivers focused, comprehensive information on prostate and GU cancer drawn from the world's leading cancer textbook, DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology . Covers the molecular biology of the kidney, bladder, and prostate; genetic testing in urinary tract cancers; and cancers of the kidney, bladder, ureter, renal pelvis, prostate, urethra, penis, and testis . Discusses in detail the growing importance of prevention and screening , giving you the understanding you need to improve your patients' chances for a healthier, cancer-free life. Explains how the latest developments in biologic therapy applies to cancers of the prostate and GU system. Provides exhaustive coverage of combined modality cancer treatment , helping you determine when and how to integrate modalities in patient treatment. Ensures that you're fully up to date thanks to easy, mobile access to quarterly updates . Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like: Complete content with enhanced navigation Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web Cross-linked pages, references, and more for easy navigation Highlighting tool for easier reference of key content throughout the text Ability to take and share notes with friends and colleagues Quick reference tabbing to save your favorite content for future use
This book focuses on the state of the art in fully grasping precocious puberty and its consequences, incorporating advances in the areas of endocrinology, genetics, imaging and therapeutics to offer an indispensable tool for all physicians interested in the latest advances in this field. The authors present the latest findings on early puberty in girls and boys. The dynamic process of maturation is influenced by many signals and reshapes growing children's role within their environment. Readers will benefit from the educational value and level of depth of the individual chapters; written by respected experts and in a self-contained format, they can also be read separately to address specific interests.
No current book tells the clinician how to handle a patient with infertility and abnormal semen analysis who arrives in front of him or her in the infertility clinic. The time is right for a new book that looks at the clinical aspects of this subject only and which is directed specifically at the clinicians. One must remember that the majority of clinicians that treat male infertility are gynaecologists who, unlike the author have had no training whatsoever in urology. The problem of examining let alone treating the infertile man is therefore very daunting.
This atlas provides a comprehensive, state of the art review of the use of multiparametric MRI (mpMRI) for the imaging of prostate cancer, covering aspects from diagnosis and loco-regional staging through to the role of the technique after treatment and follow-up. The book contains a wealth of high-resolution images, many of them in color, and displays the anatomical-MRI-pathological correlation whenever appropriate. Readers will find a helpful overview on the current standardized method for reading and reporting on mpMRI, the Prostate Imaging Reporting and Data System (PI-RADS), version 2. Dedicated chapters focus on differential diagnosis and imaging pitfalls, and the inclusion of helpful diagrams and algorithms will further assist in image interpretation, enabling readers to ease and improve their use of mpMRI. Edited and written by very experienced radiologists, pathologists, and urologists; the Atlas of Multiparametric Prostate MRI will serve as a unique source of clinically relevant information and an aid to disease management for radiologists, urologists, pathologists, radiotherapists, and oncologists.
In "A Woman's Guide to Pelvic Health" a urologist and a physical therapist offer expert and reassuring advice to women. For example, one of every four women suffers from urinary incontinence, the involuntary leakage of urine. Elizabeth E. Houser and Stephanie Riley Hahn want these women to know that they do not have to cope in silence with this embarrassing problem, limit their lifestyle, or spend thousands of dollars on adult diapers.
Symptoms involving the pelvic floor, including urinary incontinence, pelvic organ prolapse, and decreased sexual sensation, can occur at any age. A wide range of treatments, such as targeted exercises, nutrition, and acupuncture, as well as medications and surgical approaches, can bring relief. Case studies and illustrations help readers explore the cause of their own symptoms and how treatments work. "A Woman's Guide to Pelvic Health" encourages women to address their pelvic floor issues and reclaim their lives.
Sexual and Reproductive Health at a Glance provides a highly-illustrated, visual introduction to all aspects of sexual and reproductive health, from basic clinical examination skills to the management of acute Sexually Transmitted Infections (STIs) and unplanned pregnancy. Covering topics which are often difficult to access as an undergraduate or junior doctor, Sexual and Reproductive Health at a Glance focuses on the fundamental principles in delivering effective contraception and sexual health care. It features high-yield information on the essential clinical topics covered in the Community Sexual and Reproductive Health (CSRH) curriculum. Presented in the familiar, easy-to-use, at a Glance format, Sexual and Reproductive Health at a Glance: Provides a quick revision of basic anatomy, physiology and clinical skills Offers balanced coverage of both male and female GU pathology, STIs and contraception Includes material on practical gynaecological procedures performed in the out-patient setting Presents a holistic approach to issues dealt with in this specialty Takes a global perspective by addressing SRH issues in different cultures and resource-limited settings Includes a companion website at www.ataglanceseries.com/sexualhealth featuring a selection of case scenarios and interactive flashcards for self-test This brand new title will provide an invaluable resource for medical and healthcare students, junior doctors, SRH trainees and busy clinicians working in other specialties.
Case Studies in Urological Cancer builds in the success of Dr Harnett's previous Case Studies in Breast Cancer, which has established itself as a key title for anyone involved in diagnosis and care of the patient with breast cancer.Featuring over 30 detailed case studies, with comprehensive explanatory text and full colour illustrations, throughout, this book provides any healthcare professional involved in urological cancer with a selection of thought-provoking, practice-changing problems in this common malignant condition.To ensure a multidisciplinary perspective, and the most comprehensive coverage possible, Dr Harnett is assisted for this volume by two co-authors, one a urological surgeon and one a urology nurse, both with many years experience of front-line patient care. ------------------------------------------------------------ -------------------- Key features Case study format gives access to important clinical information in an easily understood and digestible way Following on from the success of Dr Harnett's previous Case Studies in Breast Cancer (1-841100-54-4, published December 2001, $49.95), which has established itself as a key title for anyone involved in diagnosis and care of the patient with breast cancer, this book features over 30 detailed case studies, with comprehensive explanatory text and full color illustrations. Will provide any healthcare professional involved in urological cancer with a selection of thought-provoking, practice-changing problems in this common malignant condition. To ensure a multidisciplinary perspective, and the most comprehensive coverage possible, Dr Harnett is assisted for this volume by two co-authors, one a urological surgeon and one a urology nurse specialist, both with many years' experience of front-line patient care.
Around 32,000 men in the UK are diagnosed with prostate cancer each
year. It differs from most other cancers in the body, in that small
areas of cancer within the prostate are very common and may not
grow or cause any problems for many years. It is often it is
diagnosed during a routine checkup so most men that are diagnosed
often have no warning signs.
Das Standardwerk der urologischen Onkologieaktualisiert in 6. Auflage
Die Uroonkologie" bietet dem Leser vollstandige und umfassende Information zu allen Bereichen des Themas:
alle Grundlagen fur eine erfolgreiche Therapie von Molekularbiologie uber Studienplanung bis zu alternativen Therapieansatzen,
alle Details zur Diagnostik, Indikationen, Durchfuhrung und Ergebnis der verschiedenen Therapieansatze aller urologischen Tumorerkrankungen.
Zusammenfassende Bewertung der Therapien am Ende jedes Kapitels.
NEU: Neugliederung des Inhalts zur besseren Orientierung mit neuen und komplett uberarbeiteten Kapiteln zu Themen wie:
. Inkontinente- und Rektale Harnableitung
. Komplikationsmanagement bei Immun- und Chemotherapie
. Sexualitat und Krebs
Eine praxisnahe, klare Sprache, viele Tabellen und instruktive Abbildungen erleichtern das Lesen. Zahlreiche Therapie- und Nachsorgeschemata sorgen fur eine schnelle Orientierung und ermoglichen die direkte Umsetzung in die tagliche Praxis.
Als Autoren wirken die anerkannten deutschsprachigen Experten zum Thema.
Rubben: Uroonkologie - Das Buch, an dem kein onkologisch tatiger Urologe vorbeikommt "
In many centers of excellence in Urology, robotic prostatectomy has become the first choice for the surgical treatment of localized prostate cancer owing to benefits such as reduced pain and minimization of impotence and incontinence. This atlas, specifically designed for use by surgeons, provides a beautifully illustrated, step-by-step guide to all aspects of the procedure. The various techniques that can be employed to achieve excellent oncological and functional results are carefully depicted in appropriate detail; for example, nerve-sparing techniques, bladder neck reconstruction, and approaches aimed at the early restoration of continence are clearly described. Special situations, such as prior prostate surgery, a large prostate, and salvage prostatectomy, are also fully covered. The information contained in this atlas will be of great value in enabling surgeons to improve their results and to take full advantage of the benefits of robotic prostatectomy compared with open prostatectomy.
This book outlines potential situations faced by those using laparoscopy and provides solutions for difficult conditions. Extensively and thoroughly written by experts in the field, Difficult Conditions in Laparoscopic Urologic Surgery enables the practising surgeon to confront and resolve dilemmas before even entering the operating theatre. In this book, every urologic procedure is described using a step-by-step sequence of events and the text is supplemented with numerous tips, illustrations, and high definition photographs depicting the main steps of the procedures. With a problem-oriented approach, Difficult Conditions in Laparoscopic Urologic Surgery is a valuable reference source for residents, fellows, and general urologists.
The rapid advances in medicine over the last 50 years have totally changed the outlook for children with disorders of sex development (DSD), but there is still much to learn. This book crystallizes the combined experience of a leading dedicated unit over 25 years in delivering expert medical and surgical care to children with DSD in a holistic environment. It documents the most recent advances in the molecular biology and embryology of sex development, and describes each disorder in detail. The clinical presentation and approach to diagnosis are described both for babies and for children presenting later in childhood or at adolescence. The chapters on management highlight all the latest knowledge and include the shared wisdom of the authors on current controversies, such as the timing of surgical treatment. Finally, the authors describe their short-, medium-, and long-term outcomes, which demonstrate the strengths of holistic team management.
Following on from the first book entitled 'Conservative treatment of Male Urinary Incontinence and Erectile Dysfunction' this book has been expanded to include seven new chapters and existing chapters have been extensively updated. It is written primarily for those specialist continence physiotherapists who are unsure of the treatment for male patients with lower urinary tract symptoms.
The classification of male urinary incontinence has been restructured in line with the International Continence Society standardisation of terminology. The subjective and objective physiotherapy assessment is covered chronologically, to enable the clinician to conduct a meaningful investigation and arrive at a logical diagnosis.
This book covers all the practical issues related to the interpretation of prostatic biopsies in day-to-day practice, including: biopsy sampling and processing; the diagnosis of limited cancer; differentiation of prostate cancers from benign lesions and recognition of histologic variants; the recognition and clinical significance of atypical diagnoses and HGPIN; the identification of recently described entities; the contemporary approach to Gleason grading; the utility of immunohistochemical markers and emerging molecular markers; and the reporting of prostate biopsies. Algorithms, flow charts, and tables are used throughout to simulate the thought and decision-making process upon encountering common clinical scenarios during sign-out of prostate biopsy. The book is richly illustrated with carefully selected, high-quality color images and will appeal especially to practicing surgical pathologists as well as pathology residents and fellows in training.
The authors aim to provide essential information on various clinical cases on urological cancers. The main messages are well referenced and the texts phrasing is written in a simple and user-friendly style. The book also contains summarizing tables and high quality original pictures. Several expert panels (American Urologists Association, European Association of Urologists, Association Francaise des Urologues, etc) are proposing guidelines aiming at providing detailed recommendations to the Urologists facing difficult urological scenarios and no significant discordance exist between them since they are all based on the existing published studies dealing with different aspects of the urological cancers.
This volume focuses on those rare congenital or acquired kidney pathologies that are localized in only one part of the organ, while the rest of the organ remains unaffected. It helps readers identify the segmentary stage of the disease and discusses in-depth possible conservative surgical approaches: partial nephrectomy, calicectomy and lobectomy. It is a valuable resource for urologists, nephrologists and surgeons as well as researchers and practitioners involved in the field.
Despite the wide prevalence of urogynaecological problems, in clinical practice, there is a paucity of specialists that are skilled in the management of these conditions. The recognition of the need for a specialist to deal with these specific problems has led to the recent evolution of urogynaecology as a subspecialty. This book, Principles and Practice of Urogynaecology aims to equip the practicing professionals - Gynaecologists, Urogynaecologists and Urologists, with up-to-date information on the principles that guide the evaluation and management of pelvic organ prolapse and other common urogynaecological problems. With an emphasis on evidence based medicine, the book aims to deliver guidance on management of common urogynaecological problems and provides information on the latest cutting-edge surgical techniques. Written by global experts in the field of urogynaecology, the book focuses initially on pelvic floor anatomy and function, moving seamlessly to the evaluation and management of clinically relevant pelvic floor problems. A detailed discussion on management of mesh related complications is a highlight.
Kidney stone is a significant disease with a 12-15% prevalence in the United States. Patients with a history of stones have a 50% risk of making another stone in 5 years or 80% risk in their lifetime. The goal of this book is to educate the reader on the nuts and bolts of stone disease and to provide new and updated information to help them tackle this painful disease.
Over the past decade, the understanding of the processes involved in the regulation of gonadotropin-releasing hormone and its dysfunction has greatly increased. As new regulatory peptides have been identified, the underlying causes of central hypogonadism have multiplied, and the area has become increasingly complex. The reversibility of even genetically determined hypogonadotropic hypogonadism has become more firmly established, and clinical studies have greatly expanded our understanding of basic physiological pathways. Structuring this mass of new knowledge in thirteen comprehensive chapters, a group of renowned experts, representing the principal international research groups, take stock of the most recent progress. This up-to-date overview helps scientists and clinicians to plan future research and treat patients with delayed puberty, hypogonadotropic hypogonadism and other forms of central reproductive disorders.
This thesis focuses on the synthesis and vaccine evaluation of the prostate tumor- associated carbohydrate antigen RM2. The author first presents the use of the [1+2+3] one-pot sequential strategy to successfully synthesise the RM2 antigen and its analogues as single stereoisomers in every glycosylation step, producing good yields and stereoselectivity. He then introduces the conjugation of the synthetic RM2 antigen to the carrier protein CRM197 in an average number of 1-10 to create the prostate cancer vaccine candidate, which is combined with -galactosylceramide C1, its analogue C34, or Alu. The results of the vaccination studies in mice are also described and indicate that the strongest anti-RM2 antigen titer is exhibited when one molecule of diphtheria toxin (DT) is conjugated with an average of 4.7 molecules of RM2 antigen (DT-RM4.7) and adjuvanted with the glycolipid C34. More importantly, the induced mouse antibodies mediate the effective complement-dependent cytotoxicity (CDC) against the prostate cancer cell line LNCap. The study presented in this thesis is the first ever to successfully synthesize this complex glycan molecule. Owing to the steric hindrance of the adjacent sialyl moiety, the introduction of two sialic acid units to the compact and rigid 3,4 di branched galactoside unit is very challenging and the ss-selective and efficient glycosylation of the galactosamine moiety at the 4-position of di branched galactose is also problematic.
Female Pelvic Surgery: A Comprehensive Guide provides a comprehensive, state-of-the-art surgical review of this field and will serve as a valuable resource for clinicians and surgeons. The text reviews the basic indications for treatment and details the many surgical approaches to the management of all pelvic floor disorders. In addition to step-by-step description in text, the volume provides illustrations/photographs of surgical techniques. Integration of surgical videos demonstrating the major repairs described in each section augment the textbook and serve as the ultimate format for the education of clinicians and surgeons. Female Pelvic Surgery: A Comprehensive Guide provides a concise and comprehensive review of all the surgical approaches to female pelvic surgery and thus it will serve as an extremely useful resource for physicians dealing with and interested in the treatment of pelvic floor disorders.
Treatment of Benign Prostatic Hyperplasia: Modern Techniques is an up-to-date review of modern techniques used to treat benign prostatic hyperplasia. It provides a comprehensive review of both office and operating room based techniques. Both electrosurgical and laser based techniques are covered. These include high powered 532 nm laser photoselective laser vaporization of the prostate (PVP), holmium laser enucleation/ablation of the prostate (HoLEP/HoLAP), and Bipolar Electrovaporization of the Prostate (Bipolar EVP/Bipolar TURP). In addition, a comprehensive review of office based techniques and future therapies currently being developed is presented. Each of these techniques are presented in a balanced fashion with a focus on modern literature. Treatment of Benign Prostatic Hyperplasia: Modern Techniques will be of great value to Urologists, Urology Residents, Iternists, and Family Practitioners.
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