This book is aimed to bring the reader into the heart of the action of any health professional consulted for a patient with a neurogenic bladder (NB). Extensive textbooks of the NB exist but there is a lack of an actual practical guide for diagnosis and management of patients suffering from NB. This book provides a single source of information on consultation in neurourology. The text covers both urinary incontinence and retention resulting from NB dysfunction. The book also discusses complications of NB which include urinary tract infections, hydronephrosis, renal failure or autonomic dysreflexia. Sections address these clinical issues faced by physicians. This book provides a useful guide with comprehensive and practical instructions for all practitioners dealing with NB in their day-to-day clinical practice. It will serve as a valuable resource for those with a special interest in NB. The book reviews new data about diagnostic and management options. It also provides a concise yet comprehensive summary of the current NB guidelines from different societies. All chapters include the most up to date scientific and clinical information with the relevant level of clinical evidence and grade of recommendation.

This unique, comprehensive text on the male factor infertility experience centers on the current background, applications and techniques for intracytoplasmic sperm injection (ICSI), one of the more commonly utilized procedures in modern assisted reproduction for male infertility, offering insights into the rationale and indications for ICSI and providing an up-to-date discussion on male factor diagnostic tests and microsurgical techniques for ICSI itself. Topics covered include the role of reproductive genetics, the effects of paternal age, the assessment, development and selection of functional human spermatozoa (e.g., Comet assay), both naturally and in the laboratory, and the procedures by which these sperm are injected directly into an oocyte. Comparisons are made between efficacy rates of ICSI versus conventional IVF strategies, and clinical approaches to fertilization failures following ICSI are presented, and intracytoplasmic morphologically selected sperm injection (IMSI) is discussed in detail in a chapter of its own. Bringing together the latest evidence and written by international leaders in the field, Intracytoplasmic Sperm Injection: Indications, Techniques and Applications is a unique and accessible resource for reproductive endocrinologists, andrologists, geneticists and infertility practitioners and researchers alike.

This book systematically reviews and discusses recent studies and articles on the immunology of female genital tract tissue. The scope is broad, encompassing innate immune responses, adaptive (humoral and cell-mediated) immunity, the immunology of menstruation, the immunology of viral and bacterial infections, the immunology of normal and abnormal pregnancy, and immunological infertility. Throughout, tables and illustrations are judiciously used to facilitate understanding. Immunology of the Female Genital Tract will serve as an invaluable source of up-to-date information for all with an interest in this subject.

The first edition laid out the foundation with laparoscopic and robotic surgery utilizing the Da Vinci SI platform. Since then, many new advances in equipment and surgical techniques are becoming more popular. This second edition expands upon laparoscopic and endoscopic techniques and robotic surgery with the use of the new Da Vinci XI platform. This book bridges the gap between the practicing community of surgeons and the surgical innovators and provides a foundation for all classic and new techniques in minimally invasive colorectal surgery. By enhancing the surgical toolbox, the surgeon is able to progress from the novice to the master. Rather than describing the entire operative procedure by an individual author, this book compares operative steps of various technical difficulties throughout different chapters, thereby allowing the surgeon to tailor surgery to patient and surgeon`s own comfort level and experience. Chapters are written by a myriad of renowned experts in the field and discuss the major advances in advanced laparoscopic and endoscopic, robotic, and transanal minimally invasive surgical techniques. Great emphasis is placed on transanal total mesorectal excision (TaTME), which is dramatically changing the surgical approach to rectal resections. The second edition of Advanced Techniques in Minimally Invasive and Robotic Colorectal Surgery serves as a valuable resource to general surgeons, colon and rectal surgeons, minimally invasive surgeons, as well as residents and fellows.

Offering comprehensive coverage of this fast-changing field for more than 20 years, Urologic Surgical Pathology is an expert guide to all common and rare entities in the genitourinary system. The 4th Edition keeps you fully up to date with discussions of newly recognized tumors and terminologies, the latest classification schemes, current grading approaches, molecular alterations, and commonly used ancillary diagnostic techniques. With its clinical focus on day-to-day urological pathology sign-out and an emphasis on clinicopathologic and radiographic-pathologic correlations, this thoroughly revised uropathology reference is an excellent resource for diagnostic decision making. Includes expanded coverage of differential diagnosis for all tumor types encountered in urological surgical pathology practice. Incorporates the latest TNM staging and WHO classification systems, as well as new diagnostic biomarkers and their utility in differential diagnosis, newly described variants and new histologic entities. Discusses advances in molecular diagnostic testing, its capabilities, and its limitations, including targeted therapy/personalized medicine. Covers new developments in immunohistochemistry and the latest diagnostic tumor markers. Features more than 1,600 high-quality images - all in color - including gross pictures, histopathologic and cytopathologic images, special stains, other ancillaries, drawings, and illustrations. Helps you find information quickly with a consistent chapter format; an abundance of tables, diagrams and flowcharts; boxed lists of types and causes of diseases; differential diagnosis; characteristic features of diseases; complications; classifications; and staging. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

This book clarifies and explains perineal anatomy and the pathophysiology of anal incontinence as well as applied pharmacology. It also institutes the new recommended classification of perineal tears, and describes anal sphincter repair techniques. The emphasis is on correct post-operative management, management of pregnancy following previous anal sphincter injury, and prevention of anal sphincter tears. The book will interest students, colorectal surgeons, physiotherapists, midwives, continence advisors, labour wards and lawyers.

This book is a comprehensive guide to extracorporeal stone wave lithotripsy (ESWL) that includes a step-by-step approach for treating every possible kidney stone position. The book has an easy to read structure that will help readers understand ESWL quickly. Written by leading experts who have used ESWL to treat over 23000 patients, this book brings together years of practical knowledge and expertise in one concise volume. The book aims to utilise this knowledge and allow people to independently carry out kidney stone treatment on patients. Diagrams and illustrations show the methods and techniques needed in ESWL, as well as the potential complications.

The Oxford Handbook of Genitourinary Medicine, HIV, and Sexual Health returns for a third edition, fully updated to encompass the changes in the British Association for Sexual Health and HIV, British HIV Association, and Faculty of Sexual & Reproductive Healthcare guidelines and recommendations. Developments in sexual healthcare provision, including identifying child sexual exploitation, legal obligations in regard to female genital mutilation, and gender diversity, are covered in new chapters and topics. HIV management is covered in greater detail, including PrEP for prophylaxis, drug interactions during treatment, and antiretroviral toxicity, with expanded topics on managing pregnancy with HIV. More colour plates are included, to feature a greater number of common dermatological presentations in genitourinary medicine and HIV to better aid diagnosis. Maintaining the concise yet comprehensive style of the Oxford Handbook series, The Oxford Handbook of Genitourinary Medicine, HIV, and Sexual Health provides a wealth of detailed, evidence-based, and clinically focused information on all aspects of the discipline, from STI diagnosis and management to medico-legal issues. This Handbook is a key single reference work for healthcare professionals, sexual health specialists, trainee doctors, and nurses with an interest in the field, making it an indispensable resource to keep on hand at all times.

"...This represents a new refreshing and logical approach to the whole anatomy and function of the pelvic floor. The Integral Theory over the years has been debated and discussed at various scientific meetings but this is the first time that the Theory has been condensed into an exciting and readable format with excellent illustrations and diagrams. I think it is an important publication which has been long overdue..." Comment on first edition from a prominent British urogynaecologist In this 3rd edition, multimedia in the accompanying DVD is used to more fully explain how lax suspensory ligaments may cause multiple pelvic floor dysfunctions, how to diagnose which structures are causing the problem, and how to perform 'simulated' or 'virtual' operations. New insights into the pathogenesis of pelvic organ prolapse, pelvic pain, vulvodynia and interstitial cystitis are presented. The tensioned minisling as used for cystocoele, uterine prolapse, rectocoele, stress incontinence and other symptoms is described in the book and demonstrated in the DVD.

This text provides a comprehensive resource and step-by-step guide to the office based procedures that would commonly occur in an andrology practice. The main purpose of the text is to serve as a "How-to" guide for urology providers and staff to help with either initial training or as a refresher prior to performing the procedures. Written by experts in the field, each chapter begins with information on necessary equipment and shows a series of images (photos and illustrations) on key points during the procedure, including tips and tricks of the trade. Atlas of Office Based Andrology Procedures provides a valuable resource for urologists, nurse practitioners, and physician assistants in practice, residents and fellows in urological training, as well as nurses and medical assistants who help with these procedures.

This text comprehensively covers the nutritional and medical management and prevention of kidney stones. Sections address types of stones, nutritional risks, medical and pharmaceutical managements, prevention of recurrence, and special consideration of stone risks among specific diseases such as obesity with gastric bypass, chronic kidney disease, and gastric intestinal disorders. Diagnosis of kidney stones, urinalysis and biochemical indices, dietary assessment, and medical nutrition therapy for specific types of kidney stones are also included. In addition, case studies are provided in the appendix. Cutting edge research is also highlighted in regards to pharmaceutical treatments and epidemiological findings in nutrition and kidney stones. Nutrition in Medical Management of Kidney Stones will be a practical resource for health professionals in the fields of nutrition, nephrology, urology, and general medicine, as well as medical students, resident physicians, and allied health clinicians whose research, practice, and education includes nutrition and kidney stones.

This book is written by a high-skilled specialist with huge experience in diagnosis, therapy and surgery for urogenital tuberculosis UGTB is the second most common form of TB in countries with a severe epidemic situation and the third most common form in regions with low incidence of TB. With patients living in the region of a high TB incidence rate or patients who had contact with TB or suffer from recurrent course of the disease, all urogenital tract infections should be tested for UGTB. Patients with tuberculosis, including UGTB need long multi-drug chemotherapy, and compliance depends on the drug tolerance. Anti-TB therapy for kidney TB was complicated by adverse effects in 41.0%. This book discovers ways of minimizing side effects and presents optimal regimens and surgical techniques for UGTB patients.

Written and edited by leading, internationally recognized clinicians and scientists in reproductive medicine and related fields, this unique text is a practical and comprehensive review of the clinical and scientific significance of unexplained male and female infertility and its management. The book is divided into thematic sections to ensure the most useful presentation of topics, opening with definitions and epidemiology of unexplained infertility, including discussion of the WHO's cutoff values for human semen characteristics and its ramifications. Sections covering male and female reproductive pathophysiology follow respectively, covering biological, genetic and environmental causative factors, with a subsequent section on evaluative techniques for male and female patients. Expectant, medical and surgical treatment strategies comprise the fifth section of the book, where active interventions and outcomes of each treatment modality are carefully considered. The final section discusses assisted reproductive techniques to manage unexplained infertility, such as intrauterine insemination and in vitro fertilization, as well as future perspectives. Thoughtful and enlightening, Unexplained Infertility: Pathophysiology, Evaluation and Treatment will be an invaluable resource for all clinicians and scientists working in the fields of reproductive medicine and infertility.

Today, the arsenal of high-precision or targeted radiotherapy includes a variety of techniques and approaches that, like the pieces of a puzzle, need to be put together to provide the prostate cancer patient with high-level optimized radiation treatment. This book examines in detail the role of these innovative radiation techniques in the management of prostate cancer. In addition, a variety of current controversies regarding treatment are carefully explored, including whether prophylactic treatment of the pelvic lymphatics is essential, the magnitude of the effect of dose escalation, whether a benefit accrues from hypofractionation, and what evidence exists for the superiority of protons or heavy ions. "Radiotherapy in Prostate Cancer: Innovative Techniques and Current Controversies" is intended for both radiation oncologists and urologists with an interest in the up-to-date capabilities of modern radiation oncology for the treatment of prostate cancer.

The Urinary System, 2nd Edition provides a concise and highly visual approach to the basic sciences and clinical pathology of the kidney, bladder, and ureters. This volume in The Netter Collection of Medical Illustrations (the CIBA "Green Books") has been expanded and revised by Drs. Christopher Rehbeck Kelly and Jaime Landman to capture current clinical perspectives in nephrology and urology - from normal anatomy, histology, physiology, and development to glomerular and tubular diseases, infections, urological surgeries, and cancers. It also features hundreds of radiologic and pathologic images to supplement the classic Netter illustrations, as well as new illustrations created Get complete, integrated visual guidance on the kidney, ureters, and bladder in a single source, from basic sciences and normal anatomy and function through pathologic conditions. Adeptly navigate current controversies and timely topics in clinical medicine with guidance from expert editors, authors, and the input of an international advisory board. Gain a rich, comprehensive clinical view of the urinary system by seeing classic Netter anatomic illustrations side by side with cutting-edge radiologic images, pathology slides, and the latest molecular biology findings. Visualize the timely topics in nephrology and urology, including HIV-associated nephropathy, hepatorenal syndrome, laparoscopic and robotic surgeries, and tumor cryoblation. See current clinical concepts captured in the visually rich Netter artistic tradition via contributions from Carlos Machado, MD, and other artists working in the Netter style. A reliable and effective reference on the urinary system with the visual support of Netter

This book aims to provide a guide for urodynamic investigation in individuals who have suffered spinal cord injuries. It is universally acknowledged that this type of investigation is valuable and most international guidelines consider it mandatory in patients with neurogenic bladder dysfunction. The book offers an evidence based knowledge of applicability, clinical value, and limitation, and will give the reader strong diagnostic outcomes that will benefit patients suffering from spinal cord injuries. What is presented in this book is based on expert opinions acquired over decades of urodynamic testing that have taken place in different parts of the world.

This book on pelvic floor re-education provides a comprehensive overview of the subject, along with other aspects of the clinical assessment and management of pelvic floor disorders. It is written for all health care professionals working with women with urogynecological disorders. Practical techniques of muscle assessment and investigative methodologies are reviewed and up-to-date information on anatomy and physiology is discussed. The text is clear, practical, and is written from experience in the field. An algorithmic approach takes the reader through the options for clinical evaluation and treatment.

This book discusses diffusion weighted imaging (DWI) and its evolving clinical role. DWI has frequently been used in the abdomen and pelvis but is now increasingly being used in other clinical applications, especially for the diagnostic workup of oncologic patients. Standardization and clinical validation of quantitative DWI related biomarkers is still ongoing, although efforts have been undertaken, especially in the prostate, to provide standardized imaging guidelines for different clinical indications. The technical aspects and clinical applications of DWI presented focus on the respective anatomical region and its pathologies. The book is unique in providing tables of technical details (imaging protocols, artifacts, optimization techniques) for each chapter, making this complex area as simple and practical as possible. The book is intended for radiologists interested in urogenital radiology and also for radiology residents.

This book offers a practical and modern update on radioisotope therapy. Clinically oriented, it provides a thorough guide to patient management, with the latest indications and procedures for the current radioisotopic treatments. It addresses the clinical problems associated with each respective pathology, discussing the management of patients (diagnosis and non-radioisotope therapy), the radiopharmaceuticals available today, and the current radioisotopic procedures. Wherever possible, information on dosimetry is included at the end of each topic, together with a list of and comments on the most recent guidelines with their recommendations for radiometabolic therapy. The book is divided into six main sections: thyroid diseases, hepatic tumors (HCC and hepatic metastases), bone metastases from prostate cancer, lymphomas, and neuroendocrine tumors. The last section is dedicated to new perspectives of radioisotope treatment. Based on contributions from of a multidisciplinary team of specialists: oncologists, surgeons, endocrinologists, hematologists, urologists, radiopharmacists and nuclear medicine physicians, it provides a comprehensive analysis of the position of radioisotope treatments among the various therapeutic options. Readers interested in targeted therapy, radiometabolic therapy, radioimmunotherapy and radiometabolic imaging will find this book both informative and insightful.

This comprehensive, up-to-date text, which brings together the key practical elements of the rapidly evolving field of sperm DNA and chromatin abnormalities, is divided thematically into five main sections. Part I discusses human sperm chromatin structure and nuclear architecture, while part II presents laboratory evaluation of sperm DNA damage, including SCSA, SCD, TUNEL and Comet assays, and cytochemical tests. Biological and clinical factors in the etiology of sperm DNA damage are discussed in part III, including oxidative stress, abortive apoptosis, cancer, and environmental and lifestyle factors. Part IV presents clinical studies on the utility of sperm DNA damage tests, both with natural and ART-assisted pregnancies, and debates the clinical utility of such tests. Finally, part V discusses current treatment options, such as antioxidant therapy, varicocelectomy, advanced sperm processing techniques and the use of testicular sperm. We are now beginning to better understand the unique organization of the sperm chromatin, as well as the nature and etiology of sperm DNA damage. Written and edited by worldwide experts in andrology, A Clinician's Guide to Sperm DNA and Chromatin Damage is an excellent resource for reproductive medicine and REI specialists, urologists, reproductive biologists and any professional working with the infertile male.

Prostate cancer is the most frequent genitourinary malignancy that garners significant medical and media attention. Over the past decade significant new discoveries have been made that have enabled substantial improvements in screening, diagnosis and management of this disease. Importantly, there has been constant evolution of the best way to treat these patients. This text will provide a single, comprehensive reference source that incorporates all the latest information regarding prostate cancer. It will serve as an easy reference source for researchers, clinicians, individuals in training, allied health professionals and medical students regarding prostate cancer by focusing on the controversial points of debate. New data regarding PSA screening, prostate cancer biomarkers, diagnostic evaluation techniques, surveillance protocols, and treatment interventions for localized and more advanced disease will be discussed. Gaps in current knowledge and areas for future research will be highlighted. Ongoing important clinical trials which could imminently yield significant new knowledge will be discussed. Uniquely to all of the above will be the clinical scenario-based format of this text. For the practicing physician, the prostate cancer screening and treatment situations will hopefully become better understood. We will incorporate key educational concepts in the framework of patient situations with evidence-based discussions of screening, diagnosis, evaluation, and therapeutic management. To provide even more insight, we plan on a comment section from leaders in the field that will be more "opinion-based" allowing the reader to get access to experienced physicians' thought processes and practice patterns. All chapters will be authored by experts in their respective fields and incorporate original figures and illustrations to the extent possible. We anticipate that this book will quickly become the ready reference source for professionals and students in various fields with an interest in the management of a complex and multifaceted disease such as prostate cancer. The book will be comprehensive and encompass the entire the spectrum of prostate cancer. The information will be presented in a succinct and easily understandable manner so as to appeal to both scientists and clinicians.

This book provides a comprehensive and up-to-date overview of the surgical treatment of pelvic organ prolapse, focusing especially on issues that continue to arouse controversy. In the first section, leading experts present detailed information on the surgical anatomy, pathophysiology, and epidemiology of prolapse and also the impact of concomitant functional disorders. The second section focuses on diagnostic work-up and the third is dedicated to the various treatment options aimed at resolution of the condition. The closing chapters discuss outcome measures and analyze the effects of prolapse surgery on urinary, bowel, and sexual symptoms. In 1966 Richard TeLinde stated that, "Every honest surgeon of extensive and long experience will have to admit that he is not entirely and absolutely satisfied with his long-term results of all his operations for prolapse and allied conditions." Although many uncertainties in the field have since been resolved, some major issues still require clarification. Often it can be difficult to find the right balance between treatment effectiveness in the long term and risk reduction, including with respect to complications. This book will help trainees and less experienced surgeons to make appropriate treatment choices and achieve optimal outcomes.

This book provides information on a range of issues related to prostate cancer survivorship, including; psychosexual care, health related quality of life, treatment, follow-up care, new psychosexual pathways, and acute and chronic co-morbidities. The book also covers the needs and challenges in survivorship care, the requirements of care, the future of survivorship care, and role of patient conferences. This book aims to give oncologists, urologists, and specialist nurses help in how to manage patients in the prostate cancer survivorship phase. This guidance is based on real life experiences handling prostate cancer survivorship, and is developed further through utilising the views of both health care professionals and patients.