A number of chapters present the most novel research on testicular and epididymal functions or on more general fields of hormone action and molecular cell biology as it is now a tradition. However, exceptionally, the book also contains several chapters dealing with the "Approaches and Tools in the Third Millenium." The unusual inclusion of technologies as such in the 2000 edition of the workshop was an absolute necessity, as these technologies are revolutionizing the fields of biology and medicine and, in many instances, how to do research. This volume gives the scientific community essential information about the very latest technical developments and their potential for future progress.

Urolithiasis, or stone disease occurs in 7% of women and 12% of men at some point, and these statistics are rising. Furthermore, for those who form a stone, the likelihood of a recurrence is nearly 50% within 5 years of initial diagnosis. Therefore, the need for effective, minimally invasive alternatives for stone eradication and prevention is critical. Because stone disease comprises a large part of any urologist s practice, a thorough knowledge of the pathogenesis and pathophysiology of stone disease is critical in order to understand and implement treatment strategies to prevent stone formation. Likewise, a working knowledge of the surgical treatments, instrumentation and outcomes is necessary to arm patients with sufficient information to make an informed decision and to provide the appropriate treatment modality for a given stone situation. In Urolithiasis: Medical and Surgical Management, the authors provide a complete guide to the management of stone disease from both a medical and surgical prospective. This book should be an invaluable resource for those who treat stone disease in any capacity, whether surgically or medically, acutely or long-term.

The Atlas of Robotic Urologic Surgery provides a detailed, step-by-step guide to common robotic urologic procedures for the purpose of helping novice surgeons in their transition to robotic surgery and seasoned robotic surgeons to refine their surgical technique and expand their repertoire of robotic procedures. In addition, less commonly performed robotic procedures such as those for male infertility, pelvic organ prolapse, urinary tract reconstruction and pediatrics are included. Each chapter is written by the thought leaders in robotic urologic surgery with descriptive step-by-step text, complimented by figures and intraoperative photographs detailing the nuances of each procedure. Emphasis is placed on operative setup, instrument and equipment needs and surgical techniques for both the primary surgeon as well as the operative assistant. The use of ancillary equipment and robotic instrument and endoscope exchanges are highlighted throughout the procedural text by tables designed to aid surgeons and their teams in improving efficiency. This volume will provide unique insights into robotic urologic surgery and reduce the learning curve of accomplishing these increasingly popular procedures.

Complications of Female Incontinence and Pelvic Reconstructive Surgery reviews the prevention, evaluation and management of complications arising from female pelvic surgery. Potential complications of both routine and specialized female pelvic procedures such as transvaginal slings, cystocele and rectocele repairs, urethral diverticulectomy, and transvaginal mesh repairs are reviewed. The chapters are divided by procedure allowing the reader to easily find what they are looking for. Images and figures of methods of evaluation and repair of these complications are included throughout. The volume is organized based on the specific types of surgeries performed and the user is able to look up the type of surgery performed and immediately find all of the potential complications and their treatments. This text will serve as a comprehensive guide and reference allowing the surgeon quick and ready access to information about the complications of female pelvic surgery.

There is no single certification system available Nationally or Internationally for Urological Laparoscopy. Skill training and certification are needed to protect both patients and doctors from the pitfalls of uncertified practice. The book focuses on the details of training within this field. The next step will be to agree nationally and internationally how to assess and certify the skills attained through training in Laparoscopic Urology. The Training Courses of Urological Laparoscopy takes experts in Laparoscopic Urology together from across the world to share their ideas and experience of training, from basic stems in the dry lab through to hints and tricks for problem solving in complex scenarios. The editors want to make this contribution to the literature with the aim to shortly establish robust assessment and certification globally for Laparoscopic Urologists.

Robotic Renal Surgery: Benign and Malignant Surgery for the Kidneys and Ureters provides a comprehensive review of the role of and technical considerations regarding robotic surgery for conditions of the kidney and associated conditions of the upper urinary tract. In addition to serving as a reference regarding indications, preoperative and postoperative management, complications, and evidence-based outcomes, this text also serves as a practical guide for surgeons in how to perform the complete array of robotic kidney and upper tract surgery. Included are detailed descriptions of positioning, instrumentation, and surgical steps for the surgeon newly adopting robotic surgery or for those refining their techniques. All chapters are written by recognized and published experts in the various techniques, creating an authoritative text on the subject. Robotic Renal Surgery: Benign and Malignant Surgery for the Kidneys and Ureters will be of great value to urologists, robotic surgeons, fellows in urologic oncology or endourology as well as urology residents in training and surgical nurses and other surgery team members involved in these procedures.

Western Medicine as seen today has a strong scientific basis in its development. The pathogenesis of most diseases and their symptomatology and physical signs are well studied and understood. The management of patients is based on firm understanding of these disease processes. In contrast, Traditional Chinese Medicine came about through the experience of many generations of practitioners over thousands of years. Undoubtedly, many of these treatments have proved to be effective in their own way, however, firm scientific basis is still lacking.

While most Western Medicine advocates control of disease by eradication of pathogens and surgical removal of diseased organs as in the case of cancer, Traditional Chinese Medicine seeks to improve resistance against disease. There is probably a great wealth of therapeutic value in Traditional Chinese Medicine, which has not been discovered or explored fully. By combining the knowledge of both Western and Traditional Chinese Medicine, one might be able to improve the results of efficacy of treatments and the survival of patients. The integration of Medicine from East and West will take time to evolve and will need interested physicians from different parts of the world to work closely together to realize such a possibility.

This book is an attempt to bridge the medical world of two great and ancient civilizations in their approach to the treatment of disease. It is informative with a detailed account of the history of medical development. It is highly recommended for those medical practitioners from both East and West who are interested to explore alternative medicine and research new areas of the medical frontier.

During the past quarter century there has been a renaissance of interest in the use of peritoneal dialysis as the primary dialytic modality for the treatment of children with end-stage renal disease (ESRD). The development of continuous ambulatory peritoneal dialysis (APD) has facilitated the provision of prolonged dialysis to infants, children and adolescents and has provided pediatric nephrologists worldwide with a real opportunity to administer effective dialysis therapy to all patients afflicted with ESRD. It has been more than a decade since the initial publication of CAPD/CCPD in Children. In the interim, a great deal of clinical experience with patients receiving peritoneal dialysis has been accumulated and research efforts have substantially increased our understanding of the technique. Therefore, we felt that a second edition of CAPD/CCPD in Children was propitious to update the advances of the past decade.

Providing a true integration of pathology with clinical management, this volume presents a practical, comprehensive text on benign and malignant disease of the adult bladder. Integrating pathology, surgical management, oncology and molecular study in a site-specific manner to include the urethra, urinary bladder, ureter and renal pelvis, The Urinary Tract: A Comprehensive Guide to Patient Diagnosis and Management is the first text in adult bladder disease to closely interweave multiple clinical disciplines into each chapter. For the majority of chapters, a pathologist and urologist or urologic oncologist are paired to provide the greatest integration of information for each disease process.

Clinical Research Methods for Surgeons is a comprehensive guide for the surgical scientist, and serves as both a critical review of existing literature and a reference guide for clinical research methodologies as they apply to surgery. The text addresses the clinical research questions facing 21st century surgeons, and provides clear direction on how to incorporate sophisticated research techniques into practice. In addition to the surgical generalist, this practical volume is specifically oriented to surgeons who treat unique diseases, yet have no single resource to facilitate clinical research in these specific areas.
This comprehensive and easy-to-use guide encompasses the entire process of clinical study design, application, and assessment. Part One is aimed at the young surgeon about to engage in new studies, and gives a general overview of the infrastructure of clinical research. Parts Two and Three are geared towards experienced investigators interested in pursuing clinical research and surgeons reviewing the literature for practical application. Part Two focuses on study design and related statistical issues, while Part Three is concerned with measuring and assessing the outcome of clinical studies. Part Four presents topics of interest to the active investigator, such as quality of care and cost-effectiveness analyses. Clinical Research Methods for Surgeons is relevant to both beginning investigators and established researchers, and addresses the unique concerns of surgical diseases and acknowledges that they require special approaches to deal with clinical questions.

A vast number of children in the United States are evaluated and treated for urologic conditions by urologists practicing general urology due to the relatively few fellowship-trained pediatric urologists. Pediatric Urology: A General Urologist's Guide is written specifically for general urologists as a concise and comprehensive reference of the more common pediatric urologic conditions. Other health practitioners (i.e. pediatrician, family practitioner, residents, medical students, and mid-level providers) will also find this book a key reference. Written by well-respected pediatric urologists, this volume will assist the health care provider to rapidly review the essential aspects of the physical examination, evaluation, diagnostic testing, and management while the patient is still in the office. The chapters are arranged into four sections to allow for easier access to the information: office urology, genitalia, urinary tract, and miscellaneous topics. Furthermore, the first chapter of the book will be dedicated to facts and figures (ex. normal penile and renal lengths based on age, dosing of common medications, and grading system for vesicoureteral reflux) that serves as a single source for this information. Pediatric Urology: A General Urologist's Guide offers the reader the essential information to assist them in the care of children.

Emphasizing the clinical problems surrounding urogenital tract dysfunction, this up-to-date reference details the basic science, differential diagnosis, and treatment of a wide range of neurourological conditions.
Covering recent advances in the neurobiology of the pelvic organs, the Handbook of Neuro-Urology
reviews the neural control processes that govern pelvic organs
discusses the pathogenic mechanisms behind neurological and smooth muscle disorders that produce bladder dysfunction
describes the management of impaired bladder, bowel, and sexual function after brain damage and spinal cord injury
examines various conditions that affect the autonomic nervous system and specifically result in bladder and sexual dysfunction
investigates lower urinary tract function in the elderly
suggests practical measures to manage urinary incontinence such as the use of pads, underpants, and appliances
and more!

This practical guide is a compendium of contemporary views on the development, treatment, and prevention of urinary stone disease. Emphasis is placed on utilizing current research to highlight areas of potential discovery and inspire novel approaches to easing the burden of urinary stone disease.

The subspecialty of genitourinary or pelvic pain suffers from the lack of objective data and level-1 evidence. Genitourinary Pain and Inflammation: Diagnosis and Management of GU-ITIS is a compilation of skilled creativity based upon critical review of the literature, consensus reports, and professional experiences. It includes detailed chapters that address iatrogenic causes of GU inflammation, caused by catheters, prosthetics, radiation, or chemotherapy. Chapters in Genitourinary Pain and Inflammation: Diagnosis and Management of GU-ITIS also discuss pain syndromes specific to the pelvic floor and the genitourinary system from several perspectives. Experts in the urological and gastrointestinal fields provide the specifics for gaining the basic understanding of inflammation and pains caused by infectious etiologies.

In the 5 years since the publication of Urologic Laparoscopy by the Japanese Society of Endourology and ESWL, the field has moved on apace, particularly technologically. It is with an eye on the need to disseminate the latest information on this progress that this collection has been assembled, highlighting the most recent advances in laparoscopic urologic oncology surgery. With treatment options becoming ever more complicated, it is essential to keep the prime objectives in mind - improved quality of life for the patient, minimal complications, early convalescence, and a better end result. In our effort to cover a broad range of techniques from renal cyst decortication to robotic laparoscopic camera control, we are in debt to surgeons at the forefront of treatment, not only in Japan but worldwide, and to manufacturers who are constantly innovating in their equipment. The contributors are enthusiastic in their expertise, as shown in the quality of the material they have produced.

This book provides a comprehensive analysis of the value of contrast-enhanced ultrasound (CEUS) in the diagnosis of a wide variety of pathologies. Sonography reliably identifies a wide range of diseases, and the efficacy of modern ultrasound has dramatically improved with contrast enhancement. This book covers almost all aspects of CEUS starting from basic principles and ending with features of its application in individual organs. In particular, it explores the diseases of abdominal, retroperitoneal, and pelvic organs as well as superficial structures, highlighting the characteristic features of typical findings. Focal lesions are discussed in depth, with attention to their early detection and differential diagnosis. Besides, a practical approach to the stratification of the risk of malignancies is provided. The authors summarized their own experience with CEUS in oncology, hepatology, gynecology, urology, endocrinology, and other fields of medicine. The role of CEUS in differential diagnosis of various disorders of the female reproductive system is comprehensively discussed as well. The presentation is clear and concise, and richly illustrated. The book will be a helpful tool for both residents and practitioners approaching ultrasound diagnostics, as well for more experienced radiologists and other professionals.

Peyronie's Disease: A Guide to Clinical Management is the first comprehensive book on this prevalent disorder in adult men (estimated range from 5-9 per cent) designed to clarify misconceptions and myths, provide an update on the etiology, pathophysiology and current research, provide useful information for clinical practice and hopefully stimulate further research into understanding the pathophysiology of this devastating problem. There will also be extensive attention to the current medical and surgical treatments with detail on surgical technique.

Michael J. Droller, MD and a panel of experienced clinicians bring their strong background in clinical research to bear on the assessment and management of bladder cancer. Their comprehensive discussion summarizes the state-of-the-art in diagnosis and treatment, based on the latest understanding of bladder cancer's epidemiology, carcinogenesis, and tumor markers. Topics of particular interest include the role of genetics and molecular biology in evaluating bladder cancer clinically, the evaluation of the results of systemic treatment in advanced disease, the current status of tumor markers in bladder cancer, and the means for further study in their applicability. Insightful and evidenced-based, Bladder Cancer: Current Diagnosis and Treatment provides active clinicians and clinical investigators with not only a critical survey of the rapidly expanding research in the area, but also a state-of-the-art tutorial on today's optimal assessment and treatment of bladder cancer.

Pediatric Urology: Evidence for Optimal Patient Management provides pediatric urologists the information needed for state-of-the-art patient care. Chapters are organized around pertinent clinical questions within major areas of pediatric urology, answered using the best available data while also reporting areas for which there is poor evidence. The text includes randomized controlled trials and prospective observational studies, tables that summarize important studies, and figures that illustrate algorithms with best options for management and their expected results. With an easy to use format not found in other volumes, Pediatric Urology: Evidence for Optimal Patient Management is an indispensible and unique resource for experienced pediatric urologists, pediatric surgeons, general urologists with an interest in pediatric urology, as well as fellows and residents in training.

Minimally Invasive Therapy for Urinary Incontinence and Pelvic Organ Prolapse provides a detailed insight into "when, why, what and how" of various minimally invasive surgical procedures for surgical management of SUI, OAB & POP. The volume provides detailed diagrammatic and pictorial step-by-step descriptions of the techniques and management of complications related to these procedures. This book also presents an up to date, one-stop reference for anything pertaining to MIT of these pelvic disorders. Written by experts in the field, Minimally Invasive Therapy for Urinary Incontinence and Pelvic Organ Prolapse is a comprehensive resource designed for both the urologist and urogynecologist treating patients with urinary disorders and pelvic organ prolapsed, as well as for residents in training.

In all varieties of organ transplants, early results have dramatically improved over the past two decades and failures due to acute rejection are becoming rarer. Efficient immunosuppressive regimens have been developed with the objective of very good results at 1, 3 and 5 years. Successful transplants, however, are significantly less frequent at 10 and 20 years, and many patients require retransplantation. Many factors are involved in late graft loss and it is now well recognized that, in addition to chronic rejection, a number of non-immunologic factors play a prominent role. In the case of renal transplantation, a reduced mass loss (transplantation of a single kidney, sometimes from an aged donor, ischemic injury and alteration of some nephrons in the case of early acute rejection) will result in slowly progressing chronic renal failure, even in the absence of any supplementary attack of an immunological nature. The new treatments must be analyzed in the light of their capacity to reduce these late failures. Several preventive measures can also limit both immunologic and non-immunologic factors of late transplant deterioration.