Together with Consulting Editor Dr. Samir Taneja, Dr. Badrinath Konety has put together a comprehensive issue that addresses Salvage therapies for Non-Muscle Invasive Bladder Cancer. Expert authors have contributed clinical review articles on the following topics: BCG salvage therapy: Definition and context; Who will respond to BCG? Predictors and nomograms; Identification of candidates for salvage therapy: Definition of BCG "Failure"; Predictors of response to Intravesical therapy; Precision medicine for NMIBC; Salvage therapy using BCG derivatives or single agent chemotherapy; Intravesical heated Mitomycin: Biology and clinical utility; Mitomycin derivatives in the salvage setting; Combination intravesical therapy; Intravesical gene therapy; Immunoncology as salvage therapy; Role of IDO inhibitors in salvage therapy; and Novel agents for intravesical therapy. Readers will come away with the clinical information they need to improve outcomes in patients with bladder cancer.

This book is partly based on research funded by Wereld Kanker Onderzoek Fonds based in the Netherlands and administered by the World Cancer Research Fund International grant program. Every year half a million of people worldwide are diagnosed with bladder cancer. With the recent zeitgeist of the self-empowered, intelligent patient who wishes to be well-informed, many cancer patients do not solely want to rely on decisions taken by medical practitioners, but actively participate in the journey from sickness to health or disease. While no books about the relationship between diet and bladder cancer currently exist, the poor quality of the existing information about the relationship between diet and health is shocking. Much of the information is exaggerated, not evidence-based, misleading and sometimes even incorrect. Dr. Maurice Zeegers, one of the world leading bladder cancer epidemiologists, and his co-authors set the record straight with this book on Diet and Fighting Bladder Cancer. Their aim is to provide purely evidence-based information about the relationship between diet and bladder cancer. The primary audience is bladder cancer patients who wish to be well-informed, although clinicians and healthcare workers may also find the book an interesting read. The book gives an honest reflection on what scientists know, but also what they don't yet know about how diet contributes to all stages of this important disease. Although science-based, the book is written in an easy-to-read format, illustrated with practical recipes.

In consultation with Consulting Editor, Dr. Samir Taneja, Dr. Sia Daneshmand has put together a state-of the-art issue of the Urologic Clinics devoted to Modern Management of Testicular Cancer. The issue focuses on surgical techniques and diagnostic modalities for testicular cancer. Clinical review articles are specifically devoted to the following: Imaging For Testicular Cancer; Management of Stage I Germ Cell Tumors; Management of Stage II Germ Cell Tumors; Current Management Of Disseminated GCT; Post-Chemotherapy Resection of Residual Mass in NSGCT; Indications For Surgery in Disseminated Seminoma; Growing Teratoma Syndrome; Management of The Primary Testicular Tumor; High-Dose Chemotherapy and Autologous Stem Cell Transplantation; mRna As Biomarkers For Germ Cell Tumors; Minimally Invasive RPLND: Is There a Role?; Complications of RPLND; Preservation of Fertility in Testis Cancer Management. Readers will come away with the latest information they need to optimize surgical and management outcomes in the patient with testicular cancer.

This issue of Primary Care: Clinics in Office Practice, guest edited by Drs. Gretchen Irwin and Laura Mayans, is devoted to Urology. Articles in this issue include: Dysuria; UTI and Pyelonephritis; Nephrolithiasis; Interstitial Cystitis; BPH; Urinary Incontinence; Enuresis; Erectile Dysfunction; Prostate Cancer Screening; Hematuria; and Urologic Cancers.

In consultation with Consulting Editor, Dr. Samir Taneja, Guest Editors Dr. Brian Matlaga and Dr. Ojas Shah have put together a timely look at Emerging Technologies in Renal Stone Management. The issue focuses on techniques and newer generation of lasers, fiberoptics, and imaging techniques. Clinical review articles are specifically devoted to the following: Next Generation Reusable Ureteroscopes: Fiberoptic and Digital; Single-Use Ureteroscopes; Disposable Stone Retrieval Devices; New Generation Laser Fibers; Emerging Laser Techniques for Stone Management; Ultrasonic and Pneumatic Lithotripters; Emerging technologies in lithotripsy; New technologies to aid in percutaneous access; Innovations in Ureteral Stent Technology; New imaging techniques in the Management of Stone Disease; Radiation Mitigation Techniques; Ultrasound Technology in the Management of Stone Disease; Emerging Mobile Platforms to Aid in Stone Management; and Assessing Cost-Effectiveness of New Technologies in Stone Management. Readers will come away with the latest information they need to optimize treatment and management outcomes in the patient with stone disease.

Circumcision remains as one of the most controversial topics in current urological practice. The most important argument against circumcision is the permanent change of anatomy, histology and function of the penis, with potential complications, with rates reported to be low in developed countries, whereas it may be up to 85% when circumcision is carried out by traditional circumcisers, rather than by medically trained professionals in developing countries. In some studies, reporting the complications of circumcision, primary haemorrhage was the most common (52%), whereas infection, meatal stenosis, incomplete circumcision, penile oedema, glandular injury, penile adhesions, iatrogenic hypospadias and urethral injuries were also detected at different rates. At times minor complications after circumcision which cannot be avoided even when the procedure is undertaken by specialized pediatric surgeons or urologist, in a properly equipped centres; specially if the child or his penis is congenitally abnormal, the obvious examples are, circumcising a child with an excessive suprapubic fat or a child with webbed penis or microphallus . This title aims to minimize complications of MC and to compete against its serious impact on men's' health, it will educate and teach physicians about potential complications and how they could manage it early on and avoid further patient problems This title will shed some light over the common as well the uncommon complications, which usually raise a debate about its management. There are different sets to classify MC complications: Either early, or late, minor or major, local or systemic, rare or common. Both rare and common complications will be discussed with comprehensive photos and illustrations for each complication and its operative remedy.

In consultation with Consulting Editor, Samir Taneja, the Guest Editors have created an issue that provides a current look at urologic disease in the pediatric patient. Authors represent the top academic institutions and have contributed review articles on the following topics: Antibiotic Prophylaxis; Peritransplant Management by the Pediatric Urologist; Pediatric Stone Disease; Anesthesia in the Pediatric Patient; Neurogenic Bladder/Augmentation; Fertility Issues in Pediatric Urology; Transitional Urology; Minimally Invasive Surgery Update; Exstrophy Epispadias and Global Urology; Bladder/Bowel Dysfunction; Prenatal Hydronephrosis; and Overview of DSD/Genital Surgery in Children. Readers will come away with the clinical updates they need for proper diagnosis and treatment of the pediatric patient.

The Management of Lithiasis: The Rational Deployment of Technology addresses the latest developments in the treatment of urolithiasis and biliary stones. The emphasis of the book is on the selection of the cheapest and most effective treatment and is based upon the experience of editors and authors from both the Western countries as well as developing countries in Asia. With health care budgets becoming increasingly restricted, there is a growing interest in cost-controlled and effective treatment methods. This volume covers urinary tract calculi as well as biliary tract calculi, including epidemiology, etiology, choices in the management of calculi, efficacy and safety of treatment and the prevention of urolithiasis.

Since the first randomized controlled studies were conducted on medical circumcision to assess their effectiveness on reducing HIV transmission, health systems have made considerable progress in adopting this practice in their HIV/AIDS and sexual reproductive health policies. As such, medical circumcision is being adopted as an additional intervention measure to support previous practices for reducing HIV infections in various countries or settings. James Kityo's pioneering book examines contexts, processes, policy projections, and likely engagements by reviewing sexual reproductive health policies or practices, and literature on medical circumcision, and identifies existing opportunities and challenges. His book also explores the medical, gender, ethical, socio-economic, and human rights dimensions of medical circumcision as an HIV/AIDS prevention method. Following peer-reviewed studies, Kityo found compelling evidence documenting the effectiveness of medical circumcision in reducing HIV transmission, and discusses this evidence in the context of HIV/AIDS in a developing health system in Sub-Saharan Africa. The author concludes that there is a range of opportunities from research and current practice to enable policy makers to adopt medical circumcision and other interventions at their disposal in order to reduce infections from HIV and AIDS-related deaths. The author suggests feasible recommendations for implementing successful HIV/AIDS prevention programs in developing nations' health systems, including medical circumcision's gradual inclusion in health practices; stakeholder support; an elaborate review of this intervention by women, politicians, religious communities, and funding agencies. The author introduces a guided action plan, which can be used as a launch pad to enhance the learning process in the integration of medical circumcision in existing health practices.

A Comprehensive Guide to the Prostate: Eastern and Western Approaches for Management of BPH provides a multidisciplinary approach to BPH and male voiding dysfunction, presenting comprehensive guidance on management. With an equal focus on traditional, complementary and alternative medicine, and a look at novel technologies, a complete understanding of the BPH disease process is revealed. Abstracts and references in every chapter make the connection between research and practice. Perfect for researchers and urologists, this must-have reference provides what is needed to understand BPH and male voiding dysfunction.

This issue of Medical Clinics of North America, guest edited by Robert E. Brannigan, MD, is devoted to Urology. Articles in this outstanding issue include: Prostate Cancer Screening; Treatment Modalities and Outcomes for Prostate Cancer; Kidney, Ureteral, and Bladder Cancer: A Primer for the Internist; Testicular Cancer: Epidemiology, Diagnosis, and Treatment; Urinary Stone Disease: Diagnosis, Medical Therapy, and Surgical Management; Male Voiding Dysfunction, BPH, and Urinary Retention; Female Voiding Dysfunction and Urinary Incontinence; Penile and Urethral Reconstructive Surgery; Male Infertility Diagnosis and Treatment in the Era of IVF/ICSI; Sexual Dysfunction: Behavioral, Medical, and Surgical Therapies; Hypogonadism: Therapeutic Risks, Benefits, and Outcomes; Cutaneous Diseases of the External Genitalia; Urological Emergencies; Telemedicine: Early Experience in the Urology Clinic; and Men's Health Programs: The Intersection of Internal Medicine and Urology.

This issue of Physician Assistant Clinics, Guest Edited by Todd J. Doran, Ed.D., PA-C, DFAAPA, is devoted to Urology. Articles in this issue include: Male Factor Infertility; Elevated PSA/PCa Screening; PSA Recurrence/Advanced PCa; Hematuria; Kidney Stones; Frequent Urinary Tract Infection; Female Urinary Incontinence; Lower Urinary Tract Symptoms (LUTS); Erectile Dysfunction; Hypogonadism; Neurogenic Bladder; and Vesicoureteral Reflux.

Dr. Cookson has put together topics and authors that speak to current knowledge on urinary diversion. Top experts provide timely clinical reviews on the most relevant information to urologists performing this surgery. Articles are devoted to the following topics: Patient Selection and Counseling for Urinary Diversion; Perioperative Preparation and Nutritional Considerations; Male Neobladder; Female Neobladder; Continent Cutaneous Urinary Diversion; Conduit Urinary Diversion; Metabolic and Nutritional Complications of Urinary Diversion; Surgical Complications of Continent Diversion; Intracorporeal Urinary Diversion; Secondary Tumors after Urinary Diversion; Quality of Life in Urinary Diversion; Urinary Diversion in Renal Transplant Patients; Urinary Diversion in the Pediatric Patients; and Tissue Engineering and Conduit Substitution. Readers will leave with the current information they need to manage patients surgically and clinically.

Dr. Samir Taneja, Consulting Editor, is stepping into the Guest Editor role for this issue of Urologic Clinics devoted to Prostate Cancer. He has assembled top experts to address the latest advances in the diagnosis and treatment of prostate cancer. Articles are devoted to the following topics: Whom to Biopsy: Pre-Diagnostic Risk Stratification with Biomarkers, Nomograms, and Risk Calculators; How to Biopsy: Transperineal vs. Tranrectal, Saturation vs. Targeted: What's the Evidence; Pre-Diagnostic Risk and Assessment with Imaging and Image-guided Biopsy; Whom to treat: Post-Diagnostic Risk Assessment with Gleason score, Risk Models, and Genomic Classifier; Strategies for Staging and Utilization of Imaging; Contemporary Active Surveillance: Candidate Selection, Follow-up Tools, and Expected Outcomes; Focal Ablation of Early Stage Prostate Cancer: Candidate Selection, Treatment Guidance, and Assessment of Outcome; Extent of Lymphadenectomy at Time of Prostatectomy: An Evidence-based Approach; How to Radiate the Prostate: Hypofractionation, Sterotactic Body Radiation Therapy, and Conventional Intensity-Modulated Radiotherapy; Managing Relapse after Surgical Therapy: Adjuvant vs. Salvage Therapy; Newly diagnosed Metastatic Prostate Cancer - Has the Paradigm Changed; Role of Local therapy in Oligometastatic Prostate Cancer: Should we Expect Cure; Approaching the High-Risk Patient; and Castration-Resistant Prostate Cancer: An Algorithmic Approach. Readers will come away with state-of-the-art information on strategies for diagnosing, treating, and managing prostate cancer.

Benign prostatic hyperplasia and the resulting lower urinary tract symptoms is a major part of almost any urologist's clinical practice. Due to the high prevalence of the disease in our aging population, new concepts and treatments are constantly entering the marketplace. Differences in patient preferences and desired outcomes require the practicing urologist to understand not only the pathophysiology of the disease but how specific treatments may be better suited for some patients and not others. This issue will address the current concepts and treatments available to urologists.

The relationship between testosterone and prostate cancer physiology resulted in a Nobel Prize almost 5 decades ago; scientists have been studying testosterone and its relationship to heart health, diabetes, bone density, and muscle development throughout the subsequent 50 years. Included in this issue is the clinical experience and research expertise of many of the leaders in this field.

This issue of Clinics in Geriatric Medicine is devoted to Geriatric Urology. Guest Editor Tomas L. Griebling, MD, MPH has assembled a group of expert authors to review the following topics: Non-Surgical Treatment of Urinary Incontinence in Elderly Women; Outcomes of Surgery for Stress Urinary Incontinence in Older Women; Evaluation and Management of Pelvic Organ Prolapse in Elderly Women; Underactive Bladder in Older Adults; Translational Research and Voiding Dysfunction in Older Adults; Functional Brain Imaging and Voiding Dysfunction in Older Adults; The Role of Urodynamics in Elderly Patients; Associations Between Voiding Symptoms and Sexual Health in Older Adults; Asymptomatic Bacteriuria and Urinary Tract Infections in Older Adults; Comorbidity and Surgical Risk in Older Urologic Patients; Small Renal Masses in Older Adults; Prostate Cancer in Elderly Men: Active Surveillance and Other Considerations; Late Onset Hypogonadism and Testosterone Replacement in Elderly Men; and Contemporary Chemotherapy for Urologic Malignancies in Geriatric Patients.

Handbook of Endourology contains five focused, review-oriented volumes that are ideal for students and clinicians looking for a comprehensive review rather than a whole course. Each volume is easily accessible through eBook format. Topics covered review both the endourological diagnosis and treatment of prostate, urethral, urinary bladder, upper urinary tract, and renal pathology. All chapters describe the most recent techniques, review the latest results, and analyze the most modern technologies. In the past ten years, the field of endourology has expanded beyond the urinary tract to include all urologic minimally invasive surgical procedures. Recent advancements in robotic and laparoscopic bladder surgery make this one of the fastest moving fields in medicine. As current textbooks are too time-consuming for busy urologists or trainees who also need to learn other areas of urology, this collection provides quick references and over 4000 images that are appropriate for fellows as well as those teaching in the field.

The Guest Editors created a unique focus to the general topic of infectious diseases. They have focused on contemporary management of antibiotics used for procedures and infections. Articles are devoted to:Update on Antibiotic Prophylaxis for GU Procedures in Patients with Arificial Joint Replacement and Artifical Heart Valves; Asymptomatic Bacteriuria; Urinary Tract Infection and Bacteruria in Pregnancy; Resistance Patterns in Contemporary Antibiotics: ESBL and Beyond ; UTI and Neurogenic Bladder; Modern Guidelines for Skin and Bowel Prep for Open and Laparascopic GU Surgery; Work up of Pediatric Urinary Tract Infection; Pre Prostate Biopsy Rectal Culture and Post Biopsy Sepsis; Infection with Foreign Bodies: Mesh and Prostheses; Treatment of the Infected Stone; Sexually Transmitted Infections: Updated Guidelines and Treatment; Bacteruria/UTI in the Elderly; Treatement of Fungal Urinary Tract Infection; and STDs.

The past decade has been marked by the acceleration of our understanding of the molecular biology of cancer. Simultaneously, there have been increasing exigencies to diagnose, treat and follow cancer patients more economically. Biomarkers represent the marriage of science and economics. Biomarkers offer the potential to increase the precision of diagnosis, prognosis, and surveillance of urological malignancies. This issue presents the cutting-edge advances of biomarker technology to urologic oncology.

Handbook of Endourology contains five focused, review-oriented volumes that are ideal for students and clinicians looking for a comprehensive review rather than a whole course. Each volume is easily accessible through eBook format. Topics covered review both the endourological diagnosis and treatment of prostate, urethral, urinary bladder, upper urinary tract, and renal pathology. All chapters describe the most recent techniques, review the latest results, and analyze the most modern technologies. In the past ten years, the field of endourology has expanded beyond the urinary tract to include all urologic minimally invasive surgical procedures. Recent advancements in robotic and laparoscopic bladder surgery make this one of the fastest moving fields in medicine. As current textbooks are too time-consuming for busy urologists or trainees who also need to learn other areas of urology, this collection provides quick references and over 4000 images that are appropriate for fellows as well as those teaching in the field.

Kidney Development, Disease, Repair and Regeneration focuses on the molecular and cellular basis of kidney development, exploring the origins of kidney lineages, the development of kidney tissue subcompartments, as well as the genetic and environmental regulation of kidney development. Special coverage is given to kidney stem cells and possible steps towards kidney repair and regeneration. Emphasis is placed on the fetal origins of postnatal renal disease and our current understanding of the molecular basis of damage and repair. Biomedical researchers across experimental nephrology and developmental biology will find this a key reference for learning how the underlying developmental mechanisms of the kidney will lead to greater advances in regenerative medicine within nephrology.

This encompassing volume gathers contributions by renowned experts in the field of pediatric urology to offer a systematic and complete review of the field. The book opens with a general section covering the basis of renal function from the fetus to adulthood, diagnostic imaging, anesthesia and infections. In subsequent sections on the kidneys, upper urinary tract, bladder, urethra and genitalia, specific anomalies are described in depth, from embryological, clinical and diagnostic aspects through to surgical treatment options. Detailed attention is devoted to the role of new technologies such as endoscopic and robotic surgery, but without disregarding the classical principles of pediatric urologic surgery. Urogenital tumors are fully covered and the book closes with a large chapter on renal transplantation. Numerous black and white and color illustrations will assist the reader in better understanding the various anomalies and the surgical procedures.