"Renal Cell Carcinoma: Clinical Management" provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in kidney cancer. The volume reviews new data about risk factors for the disease, profiles the new staging system for renal cell carcinoma (RCC), highlights our current understanding of familial syndromes of RCC and their molecular genetics, and provides new perspectives about imaging of renal tumors. For localized disease, a greater appreciation of nephron-sparing approaches and the importance of preservation of renal function is discussed in detail. Advances in surgical techniques are highlighted. For metastatic disease, the molecular biology of kidney cancer is reviewed in a concise and understandable manner, including the data that has fostered novel targeted approaches that have revolutionized management. The several landmark phase III targeted therapy trials published in the last few years are placed in context with respect to current management. Integration of surgery and systemic therapy through cytoreductive and consolidative approaches has yielded provocative data that promises to further advance the field, and major advances in this domain are also be discussed.

This comprehensive and innovative volume offers a hands-on reference for the management of challenging disorders of the female lower urinary tract. The volume features scenario presentations in which a patient presentation is described and followed by two experts in the field reviewing work-up and management of the problem. Novel techniques for the treatment of voiding dysfunction are provided.

Bladder Dysfunction in the Adult: The Basis for Clinical Management succinctly describes all that the healthcare professional needs to know when treating lower urinary tract symptoms. The book describes how to assess and treat every group of patients likely to be affected with bladder problems, and the underlying mechanisms responsible. Women with stress incontinence, men with enlarged prostates, people with neurological disease and the elderly are all discussed in particular detail. For all professionals treating or learning to treat patients with urinary storage or voiding problems, the concise presentation and thorough coverage provides treatment recommendations and clear explanations. Authored by recognized experts in their respective fields, Bladder Dysfunction in the Adult: The Basis for Clinical Management is a comprehensive resource that allows the reader to develop the knowledge, understanding, and confidence to deal with the many clinical challenges of bladder dysfunction.

In the 6 years since the publication of the first volume of Recent Advances in Endourology by the Japanese Society of Endourology and ESWL, data on long-term oncological or functional outcomes have been collected in several related fields, and advances in surgical techniques and improved instrumentation have led to further development of such complex surgery as laparoscopic partial nephrectomy and radical prostatectomy. This seventh volume in the series focuses on the treatment of urogenital malignancies by endourological procedures, including laparoscopic surgery with robotic assistance. The standard procedures and their relatively long-term outcomes as well as new techniques have been clearly described with detailed references. This book provides a better understanding of the present status of endourological management for urogenital carcinoma and sets the stage for future improvements in both oncological and functional outcomes.

Now in its fourth volume, the Biennial Review of Infertility brings together the most up-to-date research and clinical information on male and female infertility, emerging assisted reproductive techniques and evolving controversies in reproductive medicine. An impressive panel of contributors presents cutting-edge information in a clear and well-balanced manner. Volume 4 discusses hot topics in contemporary reproductive medicine, including stem cell technologies for male infertility, the current state of ovarian tissue cryopreservation and time-lapse video microscopy of embryos. The expanded section on controversies allows for point/counterpoint discussion between experts with differing opinions on topics like eSET and the use and role of dietary supplements in IVF cycles. Created to provide an ongoing appraisal of current knowledge, the Biennial Review of Infertility stimulates communication amongst all clinicians and researchers working to help couples resolve their infertility.

A team of authoritative urologic surgeons reviews the latest advances in urologic prosthetic surgery and the patient management techniques needed to successfully implement them. These highly experienced clinicians fully describe each technique and process, providing proven guidelines for patient evaluation prior to its use, its surgical implantation, and postoperative treatment of the patient. The topics expertly covered range from injectable materials used in a variety of circumstances to artificial urinary sphincters, from urethral stents, penile implants, testicular and penile prostheses, to the newer penile rigidity systems.

Together with Consulting Editor Dr. Samir Taneja, Dr. Badrinath Konety has put together a comprehensive issue that addresses the latest clinical updates in Male Infertility. Expert authors have contributed clinical review articles on the following topics: Cutting edge evaluation in male infertility; Optimal endocrine evaluation and treatment; Sperm extraction in obstructive azoospermia: What's next; FNA vs. microTESE; ROSI (round spermatid injection); Reproductive Urology in the context of an IVF practice; Care delivery in male infertility; Qualitative research in male infertility; Male Infertility & Somatic Health; DNA fragmentation: Does testicular sperm make sense; CRISPR & Genetics of Male Infertility after whole genome sequencing; Transgenerational epigenetics: A window into paternal health influences on offspring; Spermatogonial Stem Cell Culture in oncofertility; Personalized medicine for the infertile male; and Male Infertility & The future of IVF. Readers will come away with the clinical information they need to improve outcomes in patients with infertility.

"Surgical Guide to Circumcision" is a compendium of the who, what, where, why, and most importantly, the how of circumcision. Given that one third of the world s males have undergone this most ancient of surgical procedures, a contemporary resource on the subject is in order.

Most circumcisions are elective with no acute medical necessity; that is, most are done for cultural reasons. Thus, in addition to being a standard surgical guide for those who perform circumcision, this book is an anthology of circumcision, from its prehistoric roots to its present day admixture of religion, culture, and medicine.

"Surgical Guide to Circumcision" is a fully illustrated, step-by-step guide to the most common techniques of circumcision and addresses aspects such as informed consent, religious and cultural sensitivities, pre-exam, post-care, pain control, and prevention and management of potential complications.

Written by experts in the field, "Surgical Guide to Circumcision" will appeal to family physicians, pediatricians, obstetricians, midwives, nurses, urologist, and anyone with a general interest in circumcision. "

The 3rd edition of this popular text covers all aspects of continence, focusing on continence promotion and measurement of outcomes. The core chapters follow a standard structure for ease of use, and case studies are used throughout to link theory to practice. contains the latest developments in continence treatment incorporates the most recent NHS guidelines on continence management and current legislation includes international perspectives provides a resource for practitioners caring for all client groups in the community and hospital environments a website providing practical documentation along with downloadable charts and examples of continuing professional development activities a new chapter on vulnerable groups, including the frail elderly, and mental health and neurological problems points for continuing professional development at end of every chapter research evidence to guide practice

Genital prolapse, or pelvic organ prolapse, occurs when the structures of the pelvis protrude into the outside vaginal canal. Genital Prolapse and Urinary Incontinence is the first book of its kind dedicated specifically to genital prolapse and is filled with every different type of prolapse, including the bladder, uterus, rectum, and the mucosal fold containing the intestine. Covering all aspects of this defect while emphasizing the managed care of genital prolapse, this text also explores both surgical and non-surgical treatments, which include methods for the diagnosis and treatment of all abnormalities. This source examines:

Current knowledge concerning both morphological and functional cryptorchid-related alterations in the various testicular compartments is summarized in this valuable new publication. Damage to the germinal epithelium and resulting infertility in both humans and experimental animals as well as the degree of damage to the different stages of germ cell development is discussed. In addition, information concerning hormonal therapy and orchidopexy to reverse cryptorchid-related damage is provided. Morphological alterations in Sertoli and Leydig cells is discussed in terms of cellular hypertrophy and hyperplasia, alterations in organelle number and characteristics as well as changes in cell-cell junctional complexes. Changes in Sertoli cell and Leydig cell function, including gonadotropin binding, steroidogenesis and other metabolic alterations is also outlined,as well as the influence of altered testicular function on subsequent hypothalamic-pituitary changes. Vascular disruption, the potential role of paracrine substances and direct thermal damage, all of which may be responsible for the resulting detrimental changes in one or more testicular compartments, are considered.

Geriatric urology represents one of the largest overall sectors of care provided within the specialty of urology. As the incidence and prevalence of many clinical urologic conditions increase significantly in older adults, the practice of urology involves a need for advanced knowledge of the basic principles of geriatrics. Geriatric Urology outlines important topics in the care of elderly urology patients. The first section covers the biology of aging, changes in the genitourinary system, and common diseases including urologic conditions that may serve as warning signs of other disorders. Section two covers geriatric syndromes and implications for urologic care including frailty, polypharmacy, dementia, and wound healing. Urologic conditions in older adults are explored in detail including urinary incontinence, pelvic organ prolapse, urinary tract infection, nocturia, and benign prostate diseases. Other topics covered include obtaining informed consent, development of advance directives, palliative medicine and care of the dying patient. Geriatric Urology is of great value to urologists, geriatricians, internists, residents and family practitioners.

This book provides a comprehensive, state-of-the art review of the genitourinary tumor pathology field and the most contemporary insights regarding specimen submission, histologic morphology, immunohistochemistry, and molecular studies useful in the diagnosis of genitourinary neoplasms. Discussion of the clinical implications of pathological findings is contributed by renowned clinicians in the field. This handsome volume guides the reader through the intricacies of genitourinary tumor pathology, diagnosis, reporting, and prognosis. Written by experts in the field, Genitourinary Pathology: Practical Advances is of great value to anatomic pathologists, urologists, fellows in genitourinary pathology, as well as upper level residents training in pathology.

Nocturia: Etiology, Pathology, Risk Factors, Treatment and Emerging Therapy includes the background, prevalence, etiology, risk factors, adverse effects and morbidity, as well as current and emerging treatments related to nocturia. Often considered a normal part of aging, nocturia can often be overlooked as a risk factor associated with serious outcomes such as mortality, morbidity, negative economic implications and decreased quality of life. This book provides comprehensive information on all aspects of nocturia as well as how the emerging therapies can provide safe, effective and low-cost treatment. This is an important reference for researchers, urologists and clinicians interested in improving diagnosis and treatment of nocturia.

Scientists have reached a critical point in the development of new therapies for prostate cancer. The information gleaned from the Human Genome Project, alongside the emergence of new technologies for the use of genetic data has expanded the physician's understanding of disease progression and widened his armamentarium for prostate cancer prevention and control. This expertly-written reference thoroughly analyzes the scientific principles and methodologies behind the most recent translational therapies and provides the necessary context, data, and studies for practitioners to select appropriate candidates for treatment and effectively apply new therapies in clinical practice.

Transitional Urology is designed to fill a critical gap that exists in the published literature by comprehensively addressing the urological challenges facing adolescents and adults with complex congenital anomalies of the genitourinary system. It provides a valuable resource to pediatricians and pediatric urologists facing urological management issues beyond their expertise in their aging patients as well as technical guidance to adult urologists who may have had little or no experience caring for patients with a congenital condition. This work will service as a field guide to congenitalism, providing a "how to" approach to guide the urologist using real clinical examples for the most common and challenging urological problems encountered. It also provides a framework for the transition process from pediatric to adult-centered care, with a special emphasis on the multidisciplinary nature needed to provide patient-centered care. Specific conditions that require special consideration, including myelomeningocele, exstrophy, posterior urethral valves, and hypospadias are highlighted. Topics considered common in the general urology practice- like infertility and sexual dysfunction are addressed within the context of patients with neurological or anatomical complexity. In addition, this text reviews urological complaints for which basic clinical algorithms are well-established within the context of a congenitally-abnormal bladder. Chapters discuss how and when special testing like video urodynamnics and positional fluoroscopy may be warranted to provide critical diagnostic guidance. The text also review how typical age-related urological phenomena, like elevated PSA, hypogonadism, and BPH, may present in this subset of patients and how treatment of these conditions may be different than the general population.

While there are Pediatric Urology texts for Pediatric Urologists and for General Urologists, there are none for Primary Care Physicians. This book is written specifically for the primary care physician, the initial contact for the many children with urologic conditions. This text will assist the primary care physician in the recognition of and participation in the care of children with these common problems. These include both congenital and acquired conditions. Management may involve medical and/or surgical intervention. The contributing authors were selected for their internationally recognized expertise and straight forward educational styles. Pediatric Urology for the Primary Care Physician will significantly help our primary care colleagues in the evaluation and management of children with genito-urinary problems.

Benign prostatic hyperplasia (BPH) is an age-related, nonmalignant condition that may lead to bothersome lower urinary tract symptoms. The standard treatment of BPH has been ordinary loop transurethral prostatectomy, but new therapies have been developed as a combined result of research, technological advances, and the cumulative experience of urological surgeons. Among the most promising therapeutic alternatives to ordinary loop resection are those that deliver topical or interstitial heat to prostatic tissue. Transurethral microwave thermotherapy, visual laser ablation with the Nd:YAG laser, high-intensity focused ultrasound, and transurethral electrovaporization are some of the techniques described in this book. These innovative procedures, employed by skilled urologists using state-of-the-art instruments, hold forth the promise of improved quality of life for BPH patients and represent significant advances in the field of urology.

Every year, in the United States and the third world combined, 13.3 million boys and 2 million girls are circumcised. Whether because of perceived medical, cultural, or religious necessity, most of these parents feel they have no alternative but to allow their children to undergo this surgery. Sparking intense debate, the circumcision of children is a highly controversial and complex phenomenon that touches a variety of sociological areas, such as religious beliefs, identity issues, medical conceptualizations, fear, and superstition. The contributors to this volume comprise an international panel of experts in the fields of medicine, psychology, law, ethics, sociology, anthropology, history, theology, and politics. In 18 chapters they discuss the history of circumcision; document the physical and psychological consequences of circumcision; present the latest anatomical discoveries about the male prepuce; analyze the role of circumcision in various traditions; reveal the medical industry's investment in the practice; describe current legislative efforts to protect children from circumcision; and outline effective, culturally sensitive methods that are being implemented today to safeguard the human rights of at-risk children. For its insights into this troubling aspect of culture, Understanding Circumcision: A Multi-Disciplinary Approach to a Multi-Dimensional Problem is a critically important contribution to the growing body of literature on this subject.

This issue of MRI Clinics of North America focuses on MR Imaging of the Genitourinary System, and is edited by Dr. Ersan Altun. Articles will include: Future Perspectives in Multiparametric Prostate MR Imaging; MRI-Guided Focal Therapies of Prostate Cancer; Infectious and Inflammatory Diseases of the Urinary Tract: Role of MRI; MRI of the Perirenal Space and Retroperitoneum; Tumors of Renal Collecting Systems, Renal Pelvis and Ureters: Role of MRI and MR Urography versus CT Urography; Radiomics of Kidney Cancer; MRI of the Bladder Tumors - What Is the Incremental value of PET-MRI?; MRI of the Penis and Urethra; MRI of the Testicular and Extratesticular Tumors: When Do We Need?; MRI Evaluation of Kidneys in Patients with Renal Impairment: Non-Contrast Techniques versus Contrast-Enhanced Techniques; Classification and Diagnosis of Cystic Renal Tumors: Role of MRI versus Contrast-Enhanced Ultrasound; and more!

With collaboration of Consulting Editor, Dr. Samir Taneja, Dr. Comiter has created a very current clinical look at surgery for female pelvic reconstruction. He secured expert authors from top institutions to contribute reviews on the following topics: Injection of Periurethral Bulking agents; Synthetic Midurethral Sling; Autologous Fascial Sling; Burch Colposuspension; Management of the Eroded Midurethral sling; Surgery for Apical Vaginal Prolapse After Hysterectomy: Transvaginal Suture-Based Repair; Surgery for Apical Vaginal Prolapse After Hysterectomy: Transvaginal Mesh-Based Repair; Surgery for Apical Vaginal Prolapse After Hysterectomy: Abdominal Sacrocolpopexy; Surgery for Posterior Compartment Vaginal Prolapse: Suture-Based repair; Surgery for Posterior Compartment Vaginal Prolapse: Graft Augmented Repair; Surgery for Anterior Compartment Prolapse: Suture-Based Repair; Surgery for Anterior Compartment Prolapse: Graft-Augmented repair; Vaginal Approach to Vesicovaginal Fistula; and Abdominal Approach to Vesicovaginal Fistula. Readers will come away with the most current clinical information they need to improve surgical outcomes in female patients.

Scrotoscopic Surgery presents a systematic approach to the theory, procedures and clinical application of scrotoscopic techniques for the improved treatment of scrotal diseases. Currently, open operations remain the most common choices to treat scrotal content diseases, such as epididymal cyst and hydrocele. However, open surgeries also bring disadvantages, including discomfort, damage and complications. To solve these problems, this book presents best practices for scrotoscopic surgery, providing practitioners with tactics that will help them ensure the best outcomes for patients.

In 1996, the National Bladder Foundation (NBF) was founded by a dedicated group of physicians and researchers propeIled by the urgent need to find better treatments for bladder disease. Committed to increasing bladder disease research and to supporting its research community, the NBF coordinates and sponsors the International Bladder Symposium (IBS) in Washington, DC. Now considered to be a premier scientific assembly, the IBS brings together international leaders in bladder disease research to present and discuss their findings. It is the only international conference where all areas of bladder disease research are exclusively covered and where bladder disease researchers are provided with a unique opportunity to share their results and theories. IBS participants contributed the research papers included in this publication in 2000 and 2001. AIl substantial areas of bladder disease research are addressed, including oncology and ceIlular biology, neurophysiology, neurogenic bladder and incontinence, immunology, inflammation and infection, muscle, matrix and obstruction, and new frontiers and therapies of the bladder. Assembled in one publication, these papers and their findings demonstrate the high scientific caliber of the dedicated researchers in this field and the potential for significant discoveries in treatment options in the next decade.

Prostate Cancer: A Case Report discusses the prevention, treatment modalities, and side effects of the medications used to treat prostate cancer. The book presents the most appropriate information, allowing patient empowerment to make informed decisions on their choice of treatments. Through the analysis of a real case report, the book also discusses the main complication associated with prostate cancer-bone metastasis-and provides information on treatment modalities for lung and liver metastasis. Diet, physical activities and the management of stress are also discussed, as is palliative care and the use of palliative sedation when other treatment modalities have failed. Cannabis, the pros and cons of euthanasia, and concerns raised by society are also covered. Esteemed author Dr. Plourde has more than 12 years' experience working on drug safety, especially for biologic products involved in the treatment of various cancers. For more than 4 years he has suffered from prostate cancer with metastasis to the lungs and bones. During this time he has learned a lot on prostate cancer from the medical literature and from discussions with various specialists. The case report presented in this book represents his own medical history. Prostate Cancer: A Case Report provides the most relevant and up to date information on the various aspects involved in the screening, diagnosis and treatment of prostate cancer.

Dr. Holzbeierlein has created an issue devoted to the current knowledge and best practice of Bladder Cancer and Upper Tract Urothelial Cell Carcinoma. Top expert authors have written clinical reviews on the following topics: Current Staging Strategies for Muscle Invasive Bladder Cancer and Upper Tract Urothelial Cell Carcinoma; Neoadjuvant Chemotherapy for MIBC and Upper Tract UCC; Bladder Preservation Therapy for MIBC; Pre-Operative and Intraoperative Optimization of the Cystectomy Patient; Robotic Cystectomy; Robotic Nephroureterectomy; Organ Sparing Cystectomy; Lymphadenectomy for MIBC and Upper Tract UCC; ERAS Pathways; Follow-up Management of Cystectomy Patients; Quality of Life after Cystectomy; Endoscopic Approaches to Upper Tract UCC; Adjuvant Therapy in MIBC and Upper Tract UCC; and Immunotherapy in MIBC and Upper Tract UCC. The urologist will have the clinical information he or she needs to treat these patients so as to optimize outcomes.