Following on from the first book entitled 'Conservative treatment of Male Urinary Incontinence and Erectile Dysfunction' this book has been expanded to include seven new chapters and existing chapters have been extensively updated. It is written primarily for those specialist continence physiotherapists who are unsure of the treatment for male patients with lower urinary tract symptoms.

The classification of male urinary incontinence has been restructured in line with the International Continence Society standardisation of terminology. The subjective and objective physiotherapy assessment is covered chronologically, to enable the clinician to conduct a meaningful investigation and arrive at a logical diagnosis.

This book covers all the practical issues related to the interpretation of prostatic biopsies in day-to-day practice, including: biopsy sampling and processing; the diagnosis of limited cancer; differentiation of prostate cancers from benign lesions and recognition of histologic variants; the recognition and clinical significance of atypical diagnoses and HGPIN; the identification of recently described entities; the contemporary approach to Gleason grading; the utility of immunohistochemical markers and emerging molecular markers; and the reporting of prostate biopsies. Algorithms, flow charts, and tables are used throughout to simulate the thought and decision-making process upon encountering common clinical scenarios during sign-out of prostate biopsy. The book is richly illustrated with carefully selected, high-quality color images and will appeal especially to practicing surgical pathologists as well as pathology residents and fellows in training.

This book sheds new light on the physiology, molecular biology and pathophysiology of epithelial ion channels and transporters. It combines the basic cellular models and functions by means of a compelling clinical perspective, addressing aspects from the laboratory bench to the bedside. The individual chapters, written by leading scientists and clinicians, explore specific ion channels and transporters located in the epithelial tissues of the kidney, intestine, pancreas and respiratory tract, all of which play a crucial part in maintaining homeostasis. Further topics include the fundamentals of epithelial transport; mathematical modeling of ion transport; cell volume regulation; membrane protein folding and trafficking; transepithelial transport functions; and lastly, a discussion of transport proteins as potential pharmacological targets with a focus on the pharmacology of potassium channels.

This volume focuses on those rare congenital or acquired kidney pathologies that are localized in only one part of the organ, while the rest of the organ remains unaffected. It helps readers identify the segmentary stage of the disease and discusses in-depth possible conservative surgical approaches: partial nephrectomy, calicectomy and lobectomy. It is a valuable resource for urologists, nephrologists and surgeons as well as researchers and practitioners involved in the field.

Kidney stone is a significant disease with a 12-15% prevalence in the United States. Patients with a history of stones have a 50% risk of making another stone in 5 years or 80% risk in their lifetime. The goal of this book is to educate the reader on the nuts and bolts of stone disease and to provide new and updated information to help them tackle this painful disease.

Over the past decade, the understanding of the processes involved in the regulation of gonadotropin-releasing hormone and its dysfunction has greatly increased. As new regulatory peptides have been identified, the underlying causes of central hypogonadism have multiplied, and the area has become increasingly complex. The reversibility of even genetically determined hypogonadotropic hypogonadism has become more firmly established, and clinical studies have greatly expanded our understanding of basic physiological pathways. Structuring this mass of new knowledge in thirteen comprehensive chapters, a group of renowned experts, representing the principal international research groups, take stock of the most recent progress. This up-to-date overview helps scientists and clinicians to plan future research and treat patients with delayed puberty, hypogonadotropic hypogonadism and other forms of central reproductive disorders.

Female Pelvic Surgery: A Comprehensive Guide provides a comprehensive, state-of-the-art surgical review of this field and will serve as a valuable resource for clinicians and surgeons. The text reviews the basic indications for treatment and details the many surgical approaches to the management of all pelvic floor disorders. In addition to step-by-step description in text, the volume provides illustrations/photographs of surgical techniques. Integration of surgical videos demonstrating the major repairs described in each section augment the textbook and serve as the ultimate format for the education of clinicians and surgeons. Female Pelvic Surgery: A Comprehensive Guide provides a concise and comprehensive review of all the surgical approaches to female pelvic surgery and thus it will serve as an extremely useful resource for physicians dealing with and interested in the treatment of pelvic floor disorders.

This thesis focuses on the synthesis and vaccine evaluation of the prostate tumor- associated carbohydrate antigen RM2. The author first presents the use of the [1+2+3] one-pot sequential strategy to successfully synthesise the RM2 antigen and its analogues as single stereoisomers in every glycosylation step, producing good yields and stereoselectivity. He then introduces the conjugation of the synthetic RM2 antigen to the carrier protein CRM197 in an average number of 1-10 to create the prostate cancer vaccine candidate, which is combined with -galactosylceramide C1, its analogue C34, or Alu. The results of the vaccination studies in mice are also described and indicate that the strongest anti-RM2 antigen titer is exhibited when one molecule of diphtheria toxin (DT) is conjugated with an average of 4.7 molecules of RM2 antigen (DT-RM4.7) and adjuvanted with the glycolipid C34. More importantly, the induced mouse antibodies mediate the effective complement-dependent cytotoxicity (CDC) against the prostate cancer cell line LNCap. The study presented in this thesis is the first ever to successfully synthesize this complex glycan molecule. Owing to the steric hindrance of the adjacent sialyl moiety, the introduction of two sialic acid units to the compact and rigid 3,4 di branched galactoside unit is very challenging and the ss-selective and efficient glycosylation of the galactosamine moiety at the 4-position of di branched galactose is also problematic.

Treatment of Benign Prostatic Hyperplasia: Modern Techniques is an up-to-date review of modern techniques used to treat benign prostatic hyperplasia. It provides a comprehensive review of both office and operating room based techniques. Both electrosurgical and laser based techniques are covered. These include high powered 532 nm laser photoselective laser vaporization of the prostate (PVP), holmium laser enucleation/ablation of the prostate (HoLEP/HoLAP), and Bipolar Electrovaporization of the Prostate (Bipolar EVP/Bipolar TURP). In addition, a comprehensive review of office based techniques and future therapies currently being developed is presented. Each of these techniques are presented in a balanced fashion with a focus on modern literature. Treatment of Benign Prostatic Hyperplasia: Modern Techniques will be of great value to Urologists, Urology Residents, Iternists, and Family Practitioners.

Infografik erg nzend zum Buch "Das Urinsediment" von Josefine Neuendorf Fotografische und schematische bersicht der Urinsedimentbestandteile Darstellung eumorpher und dysmorpher Erythrozyten Schematische Darstellung der Gr enverh ltnisse zellul rer Urinsedimentbestandteile bersicht der Urinsediment-Normalbereiche Befundung der Urinsedimentbestandteile mittels Zahlenbereichen und Kreuzen Anleitung zur Urinsediment-Herstellung Unterst tzung f r eine gute Urinsediment-Diagnostik Sichere Pr analytik und erfolgreiche Differenzierung dank leicht verst ndlicher Anleitungen, bersichten und hochqualitativer Fotografien sowie grafischer Darstellungen Handliches Poster-Format f r den Arbeitsplatz im Labor direkt am Mikroskop Stabiles, abwaschbares und laminiertes Poster Rascher Vergleich mikroskopisch gesehener Urinsedimentbestandteile mit den schematischen und fotografischen Darstellungen Erleichterte Zuordnung schwierig zu differenzierender Urinsedimentbestandteile durch Darstellung der Gr enverh ltnisse Sichere Zuordnung dysmorpher / eumorpher Erythrozyten Weitere Inhalte und Wissenswertes zum Thema morphologische Differenzierung von Urinsedimentbestandteilen sowie weitere hochwertige Urinsedimentbilder finden Sie in den B chern - Das Urinsediment / 2. Auflage / Josefine Neuendorf - Das Urinsediment-Arbeitsbuch / Josefine Neuendorf Die Harnsedimentuntersuchung ist eine der bedeutendsten und vielseitigsten diagnostischen M glichkeit des Urologen. In den richtigen H nden kann es die wirtschaftlichste Untersuchung im Arsenal des Urologen sein, mit der man eine Plethora an Informationen schnell und kosteng nstig erlangen kann, um eine schnelle Verdachtsdiagnose zu stellen oder zu best tigen und eine sofortige zielgerichtete Therapie den Patienten anbieten zu k nnen. Ausgestattet mit einem entsprechenden Phasenkontrastmikroskop und einer hochwertigen morphologischen Referenz, kann man in jeder Praxis so, Diagnosen von der Harnwegsinfektion bis hin zur chronischen Glomerulonephritis, von der Parasitose bis hin zur der Art der Kristallurie bei Steinbildner, sowie von atypischen Zellen bis hin zur Blasen-Darm-Fistel u.v.m. stellen. Die Urinsedimentuntersuchung sollte folglich ein Bestandteil der urologischen Basisdiagnostik bleiben und jedem Urologen, sowohl in der Praxis als auch im Krankenhaus, als t gliche Entscheidungshilfe zur Verf gung stehen. Dieser morphologische Atlas der verschiedenen Bestandteile des Urins erm glicht an jedem Mikroskopier-Arbeitsplatz somit eine deutlich schnellere Diagnostik und vervollst ndigt den Einsatz des Phasenkontrastmikroskops in der Harnsedimentuntersuchung. Priv. Doz. Dr. med. Sascha Ahyai, Leitender Oberarzt der Klinik f r Urologie, Universit tsmedizin G ttingen OA Dr. med. I.V. Popeneciu, Klinik f r Urologie, Universit tsmedizin G ttingen

This book provides a comprehensive and up-to-date overview of all key issues related to kidney and urinary tract disease in full-term and premature newborns. Among the many topics addressed are fluid and electrolyte abnormalities, hydronephrosis, urinary tract infection, obstructive uropathy and renal replacement therapy. The approach throughout is clinically oriented, the aim being to provide the reader with hands-on guidance. Each chapter commences with a clinical case vignette and concludes with a take-home message highlighting key aspects of practical importance. In addition, however, informative reviews of the literature and the basic sciences are included. No other book currently on the market focuses solely on the newborn, and "Kidney and Urinary Tract Diseases in the Newborn" will be especially valuable to those undergoing fellowship training in neonatology or pediatric nephrology/urology.

Pediatric Urology: Evidence for Optimal Patient Management provides pediatric urologists the information needed for state-of-the-art patient care. Chapters are organized around pertinent clinical questions within major areas of pediatric urology, answered using the best available data while also reporting areas for which there is poor evidence. The text includes randomized controlled trials and prospective observational studies, tables that summarize important studies, and figures that illustrate algorithms with best options for management and their expected results. With an easy to use format not found in other volumes, Pediatric Urology: Evidence for Optimal Patient Management is an indispensible and unique resource for experienced pediatric urologists, pediatric surgeons, general urologists with an interest in pediatric urology, as well as fellows and residents in training.

Fully revised and expanded for its second edition, the Oxford Handbook of Nephrology and Hypertension provides clear, concise information and practical guidance on the day-to-day management of patients with renal disease. It is the essential resource for all those working with renal patients, including specialist trainees in nephrology, foundation doctors, renal nurses and general practitioners. A vital practical guide for those on the wards, and a valuable resource for all those studying for exams, this is the must-have handbook of renal medicine.
Based on the Oxford Textbook of Clinical Nephrology and companion to the Oxford Handbook of Dialysis, this handbook provides vital clinical knowledge on the full breadth of renal care. The chapters on AKI and CKD have been significantly expanded to represent their enhanced primacy in both primary and secondary care. The recent shift in understanding from acute renal failure to AKI has led to fast-paced change, and this handbook has been specifically revised to ensure the reader is up-to-the-minute in this vital area of renal care. Renal transplantation has also greatly increased in volume and complexity in recent years and a full chapter has been given to this important area, which has been thoroughly updated and greatly expanded.
Comprehensive, easy-to-use, and concise, with a strong focus on practical advice, and detailed guidance on everything from common conditions to complex clinical care, this handbook ensures that the reader always has the information they need at their fingertips.

The Urinary System, 2nd Edition provides a concise and highly visual approach to the basic sciences and clinical pathology of the kidney, bladder, and ureters. This volume in The Netter Collection of Medical Illustrations (the CIBA "Green Books") has been expanded and revised by Drs. Christopher Rehbeck Kelly and Jaime Landman to capture current clinical perspectives in nephrology and urology - from normal anatomy, histology, physiology, and development to glomerular and tubular diseases, infections, urological surgeries, and cancers. It also features hundreds of radiologic and pathologic images to supplement the classic Netter illustrations, as well as new illustrations created Get complete, integrated visual guidance on the kidney, ureters, and bladder in a single source, from basic sciences and normal anatomy and function through pathologic conditions. Adeptly navigate current controversies and timely topics in clinical medicine with guidance from expert editors, authors, and the input of an international advisory board. Gain a rich, comprehensive clinical view of the urinary system by seeing classic Netter anatomic illustrations side by side with cutting-edge radiologic images, pathology slides, and the latest molecular biology findings. Visualize the timely topics in nephrology and urology, including HIV-associated nephropathy, hepatorenal syndrome, laparoscopic and robotic surgeries, and tumor cryoblation. See current clinical concepts captured in the visually rich Netter artistic tradition via contributions from Carlos Machado, MD, and other artists working in the Netter style. A reliable and effective reference on the urinary system with the visual support of Netter

This book provides comprehensive but concise data for congenital diseases of the penis, explaining the embryological and anatomical background, incidence, historical background, investigation approaches, imaging and management of each condition. The book is organised in themed parts, starting from embryology and normal anatomy and examining anomalies for each anatomical part: prepuce, penis, urinary meatus, penile urethra with a final part of acquired penile diseases with congenital background. With clear illustrations in each chapter to explain each condition in detail, online animations for the difficult and complex cases are also provided. Practitioners in the field of pediatric urology and surgery will find this highly readable book particularly valuable. The author is a pioneer pediatric surgeon with over 30 years' experience in the field of genitourinary anomalies.

Complications of Female Incontinence and Pelvic Reconstructive Surgery reviews the prevention, evaluation and management of complications arising from female pelvic surgery. Potential complications of both routine and specialized female pelvic procedures such as transvaginal slings, cystocele and rectocele repairs, urethral diverticulectomy, and transvaginal mesh repairs are reviewed. The chapters are divided by procedure allowing the reader to easily find what they are looking for. Images and figures of methods of evaluation and repair of these complications are included throughout. The volume is organized based on the specific types of surgeries performed and the user is able to look up the type of surgery performed and immediately find all of the potential complications and their treatments. This text will serve as a comprehensive guide and reference allowing the surgeon quick and ready access to information about the complications of female pelvic surgery.

Kidney Transplants are the most frequently performed solid organ transplants. Pancreas transplantation offers unique survival and quality of life benefits to selected diabetics with or without concomitant renal failure. Usually, kidney and pancreas transplant recipients are managed by the same team of physicians and surgeons. Current textbooks dealing with kidney and pancreas transplantation are unfortunately usually in the form of introductory manuals or primers and lack crucial practical detail and scientific depth relevant to the practicing physician. The transplant physicians and surgeons at Cleveland Clinic have collaborated to produce a textbook devoted to kidney and pancreas transplantation that addresses the need for a work that is well grounded in scientific principles, quantitative clinical reasoning, clinical pharmacology, tested clinical practices and overall clinical applicability. Also addressed are key aspects in the initiation, maintenance and sustained growth of viable clinical programs in kidney and pancreas transplantation.

This issue of MRI Clinics of North America focuses on MR Imaging of the Genitourinary System, and is edited by Dr. Ersan Altun. Articles will include: Future Perspectives in Multiparametric Prostate MR Imaging; MRI-Guided Focal Therapies of Prostate Cancer; Infectious and Inflammatory Diseases of the Urinary Tract: Role of MRI; MRI of the Perirenal Space and Retroperitoneum; Tumors of Renal Collecting Systems, Renal Pelvis and Ureters: Role of MRI and MR Urography versus CT Urography; Radiomics of Kidney Cancer; MRI of the Bladder Tumors - What Is the Incremental value of PET-MRI?; MRI of the Penis and Urethra; MRI of the Testicular and Extratesticular Tumors: When Do We Need?; MRI Evaluation of Kidneys in Patients with Renal Impairment: Non-Contrast Techniques versus Contrast-Enhanced Techniques; Classification and Diagnosis of Cystic Renal Tumors: Role of MRI versus Contrast-Enhanced Ultrasound; and more!