Written and edited by leading, internationally recognized clinicians and scientists in reproductive medicine and related fields, this unique text is a practical and comprehensive review of the clinical and scientific significance of unexplained male and female infertility and its management. The book is divided into thematic sections to ensure the most useful presentation of topics, opening with definitions and epidemiology of unexplained infertility, including discussion of the WHO's cutoff values for human semen characteristics and its ramifications. Sections covering male and female reproductive pathophysiology follow respectively, covering biological, genetic and environmental causative factors, with a subsequent section on evaluative techniques for male and female patients. Expectant, medical and surgical treatment strategies comprise the fifth section of the book, where active interventions and outcomes of each treatment modality are carefully considered. The final section discusses assisted reproductive techniques to manage unexplained infertility, such as intrauterine insemination and in vitro fertilization, as well as future perspectives. Thoughtful and enlightening, Unexplained Infertility: Pathophysiology, Evaluation and Treatment will be an invaluable resource for all clinicians and scientists working in the fields of reproductive medicine and infertility.

This book provides a state-of-the-art review of the role of radiation therapy in various pelvic malignancies as well as the consequences of the radiation in the pelvic tissues. With sections covering the role of radiation therapy in the various pelvic malignancies, the pathophysiology of radiation related injury and the risk factors that increase the possibility of such an injury, and the latest in medical, endoscopic and surgical therapies for these radiation related complications the text offers a concise yet comprehensive overview of radiation therapy in the human pelvis, its role and the adverse effects on the pelvic organs. Written by experts in the field with readers in mind, Radiation Therapy for Pelvic Malignancy and its Consequences is the first of its kind standalone reference on the subject. Radiation Therapy for Pelvic Malignancy and its Consequences is of great value to urologists, medical radiation and gynecological oncologists, and gastroenterologists.

The principal role of the diagnostic surgical pathologist is to serve a patient by assisting the clinician in charge of the patient's care. In that capacity,the pathologist provides the vital informationthat should be directly and indirectly useful in guiding the clinician toward the most appropriate therapy. The material pathologists receive most commonly is a biopsy or a part of an organ removed after a definitive pro- dure. To extract useful information, pathological evaluation proceeds according to a set of guidelines. Simply reporting a diagnosis of cancer is inadequate. Detailed additional information is needed so that the clinician can go on to establish a the- peutic plan as needed. To best serve the patient, close interaction between the cli- cian and the pathologist is vital. In the field of urological pathology, there are problems specific to this system. Typically, in the prostate, because of its location, there is little room for a surgeon to work to obtain adequate resection margins, unlike with many other organs. As a result, questions arise such as "What constitutes an adequate surgical margin?" "What is the significance of extraprostatic extension of neoplasm that is still inside the resection margin?" and "What is the significance of neoplastic glands found on the resection margin marked with the ink?" It has been shown that a prostate needle core biopsy can generate much information that is immediately useful in predicting the extent of cancer in the prostate and, consequently, the outcome for the patient.

Upper Tract Urothelial Carcinoma represents the first book of its kind to be dedicated solely to UTUC. It's aim is to improve understanding and eventually care of a disease that is greatly understudied and underappreciated, yet commonly dealt with by many medical and urologic oncologists. The volume features new data regarding genetic susceptibility, gene expression studies and causative factors; contemporary concepts and controversies regarding diagnosis and staging of UTUC; prediction tools and their value in treatment decisions within each disease stage and patient selection and treatment options such as endoscopic management, distal ureterectomy, radical nephroureterectomy and chemotherapy. Up-to-date information regarding boundaries of surgical resection, indication and extent of lymphadenectomy is covered as well as the role of perioperative/neoadjuvant chemotherapy in patients with high-risk UTUC. Upper Tract Urothelial Carcinoma will be of great value to all Urologists, Medical Oncologists and fellows in Urologic Oncology as well as upper level residents in training in Urology and Medical Oncology.

This volume provides a comprehensive, state-of-the art review in the field of experimental and human nephrogenesis. The book reviews new data on the effects on kidney development by neonatal asphyxia, obstructive uropathies, nephrotoxic drugs, malnutrition, underfeeding, overfeeding and provides all possible preventive measures to ensure the well-being of the kidney at birth. The book also discusses the possible implications between renal development and the insurgence of kidney disease in adult life and the correlation with renal carcinogenesis. Written by well recognized experts in their fields, Kidney Development in Renal Pathology is a valuable tool for pathologists, neonatologists, nephrologists, gynecologists and researchers with an interest in kidney diseases.

Endometriosis is one of the most common gynecological diseases, causing pelvic pain, infertility, and cancer. The condition reduces the quality of life for the estimated 10% of menstruating women who are affected by it. This book provides a clear insight into the pathogenesis and pathophysiology of endometriosis—essential information for clinicians intending to successfully treat the condition. The first part covers a range of topics including stem cells, NK cells, macrophages, inflammation, cytokines, epigenetics, prostaglandin, sex steroids, aromatase, apoptosis, nerve fibers, and malignant transformation to aid in understanding the pathogenesis and pathophysiology of the disease. The second part provides useful tools for therapy, specifically, notable recent techniques in prevention, imaging, biomarkers, medical treatments, surgical treatments, prevention of recurrence, and infertility treatments. Each chapter was written by an expert in the field, with nearly 40 researchers and clinicians contributing to the work. This book will be highly useful to clinicians as well as to research scientists who are interested in this enigmatic disease.  

With the rising incidence of urolithiasis, the management of ureteral stones continues to become a larger component of urologic practice. Though almost all urologists deal with ureteral stones, there have been many recent improvements in instrumentation and adjunctive equipment as well as improvements in imaging and the data we can obtain from radiologic imaging in order to guide stone management. Newer topics such as how to limit radiation exposure to both the patient and the urologist, the accuracy and limitations of low-dose computed tomography as well as a review of the most recent studies will be covered in this book. The purpose of this book is to provide a complete updated roadmap to treating ureteral stones, from early management decisions from information found on radiologic studies to adjusting to intra-operative challenges.

This book will enable the reader to gain a sound understanding of contemporary and futuristic evidence-based interventions and assessment procedures for pelvic floor disorders. It gathers the experiences of some of the most important experts on electrical stimulation techniques, offering a multidisciplinary and problem-oriented approach organized according to therapeutic goals. Interventions are recommended that are consistent with theory and display clinical efficacy for specific disorders, including urinary incontinence or retention, fecal incontinence, constipation, pelvic pain, sexual dysfunction and neurological diseases involving the pelvic floor. All of the surgical or rehabilitative techniques requiring electrical stimulation for the treatment of these disorders are explored and essential background information is provided on functional anatomy, neurophysiology and concepts in electrotherapy. This volume will be a very useful tool for urologists, general or colorectal surgeons, gynecologists and anesthesiologists and also physiotherapists and alternative medicine practitioners (a specific chapter focuses on electroacupuncture). It will assist in their clinical practice as they seek to help the very many patients who suffer from any of the wide range of functional pelvic floor disorders.

Prostate cancer is by far the most common cancer in men and the second leading cause of death due to cancer. It comprises a mixed group of tumours displaying varying clinical behaviour: while some have a very aggressive course, others are rather indolent. Prevention of prostate cancer and discrimination between aggressive and indolent forms are important clinical goals and the acquisition of significant new evidence on means of achieving these aims makes this book particularly timely. A wide range of topics are covered by leading authorities in the field. The biology and natural history of prostate cancer are reviewed and the role of lifestyle and dietary factors, assessed. Detailed attention is paid to risk prediction biomarkers and to the role of novel high-throughput nucleic acid-based technologies in improving risk prediction and thereby allowing tailored approaches to cancer prevention. Potential means of chemoprevention of prostate cancer are also reviewed in depth, covering the very positive new data on the impact of aspirin as well as evidence regarding 5α-reductase inhibitors, DFMO and lycopene. Guidance is provided on the differentiation of aggressive from indolent disease and the policy and research implications of recent findings are examined. This book will be of interest to both clinicians and researchers.

During recent decades, more than 100 surgical procedures have been proposed to treat pelvic organ prolapse, and surgeons are still searching for the ideal approach. Although generally accepted guidelines and algorithms are still lacking, careful preoperative work-up and patient selection can serve as a sound basis for tailored surgery. In this comprehensive book, leading experts from around the world provide a detailed, up-to-date overview of the diagnostic and surgical approaches employed in patients with prolapse of the middle or posterior pelvic floor compartment. Each surgical technique is explained step by step with the aid of instructive figures. Guidance is also included on the management of surgical complications and of recurrent disease – aspects that are too frequently overlooked in the scientific literature. This book will prove essential reading for all who are interested in functional colorectal disorders of the pelvic floor and will represent a unique and invaluable source of knowledge for general surgeons, colorectal surgeons, and urogynecologists, whether in training or practice.   ​  

This book provides a comprehensive, state-of-the art review of the genitourinary tumor pathology field and the most contemporary insights regarding specimen submission, histologic morphology, immunohistochemistry, and molecular studies useful in the diagnosis of genitourinary neoplasms. Discussion of the clinical implications of pathological findings is contributed by renowned clinicians in the field. This handsome volume guides the reader through the intricacies of genitourinary tumor pathology, diagnosis, reporting, and prognosis. Written by experts in the field, Genitourinary Pathology: Practical Advances is of great value to anatomic pathologists, urologists, fellows in genitourinary pathology, as well as upper level residents training in pathology.

This book approaches the classification, pathogenesis, diagnostic, therapy and surgery for kidney tuberculosis as well as male genital tuberculosis. The reader will find recent data on epidemiology, many interesting history cases with illustrations and new methods for the identification of Mycobacterium tuberculosis.

Renal Cancer: Contemporary Management provides a state of the art overview of the major topics in the field of kidney cancer. The material has been collected from the most current evidence based resources to allow for the appropriate care of these patients. The sections of the book have been structured to give an overview of the major issues dealing with renal cell carcinoma and transitional cell carcinoma of the kidney. The text also reviews the new staging system, discusses familial syndromes of renal cell carcinoma, and provides new perspectives with regard to imaging and managing renal tumors. A valuable resource for physicians and researchers dealing with renal cancer, Renal Cancer: Contemporary Management provides a comprehensive summary of the field that will guide patient management and stimulate further clinical and basic science research efforts.

Patients with rare diseases, affecting less than 1 in 2000 persons, frequently experience delays or errors in diagnosis, sometimes with tragic consequences. Even after the diagnosis has been established, the quality of health care delivered is often poor. This book, which is both textbook and atlas, covers the full range of rare congenital genitourinary anomalies encountered in males and females, many of which have previously been described only in sporadic case reports. In the case of the more established anomalies, variants are presented. For each anomaly, information is provided on incidence, similar cases, clinical presentation, diagnosis, possible management and outcome. Informative supporting illustrations are presented for each anomaly, and the book will serve as an excellent reference for all pediatricians, urologists and surgeons who are responsible for the care of such patients.

In the last decade, much of the clinical interest in the field of infertility has focused on advancing reproductive techniques and has often under-appreciated the role that male sexuality plays in reproductive problems. Male sexual function is an integral part of reproduction, and the treatment of sexual dysfunction is an important component for any couple seeking fertility. In some cases, treatment of sexual dysfunction may obviate the need for more invasive cures through advanced reproductive techniques. Thanks to recent clinical and scientific advances in male sexual medicine, the management of men's sexual dysfunction is often more effective and less invasive than how it was historically described. Men's Sexual Health and Fertility is the only resource that focuses on the interplay and interconnections between male sexual dysfunction and male factor infertility, gathering insightful data from a panel of experts in male sexual medicine for clinicians who treat couples with fertility issues due to male sexual dysfunction. Chapters discuss advances in the field of men's sexual medicine, including the latest treatment for erectile dysfunction, the most up-to-date understanding of the physiology and pathophysiology of ejaculation, and the growing body of evidence that low testosterone and male infertility are intimately related. As such, this book provides important information in order to be able to better understand the link between sexual dysfunction and infertility and, most importantly, to better treat male sexual dysfunction in the infertile couple.

Management of Penile Cancer provides a comprehensive and state-of-the-art overview of the major issues specific to the field of penile cancer. The sections of the book are structured to review the overall scope of issues of penile cancer, including diagnosis and staging, surgical approaches and the treatment of advanced disease. As multidisciplinary care is an integral part of the treatment of penile cancer, this book is unique in the inclusion of collaborating authors from a variety of integrated disciplines, including urology, radiation oncology, medical oncology and reconstructive surgery. Written by recognized experts in their field, Management of Penile Cancer is a unique and valuable resource in the field of penile cancer, both for those currently in training and for those already in clinical or research practice.

This monograph covers all aspects of the radiologic diagnosis of urinary tract diverticula, including calyceal, ureteral, bladder and urethral diverticula. Characteristic and subtle diagnostic features are identified with the aid of numerous high-quality ultrasound, X-ray and magnetic resonance images, the vast majority of which are drawn from the author's personal clinical practice. In addition, issues relating to terminology, classification, statistics, etiology, pathogenesis, clinical presentation and differential diagnosis are discussed. The text is complemented by two helpful appendices that document the latest recommendations of the European Society of Urogenital Radiology regarding use of contrast media and the European Medicines Agency on minimizing the risk of nephrogenic systemic fibrosis when using gadolinium-containing contrast agents. This book will be of value for specialists in radiology and urology and also trainees and medical students.

Genitourinary Imaging - A Case Based Approach is a user friendly, portable guide that offers a comprehensive coverage of the subspecialty with an emphasis on all modalities. As subspecialty practice has become the norm in radiology, it becomes increasingly important to keep abreast of the latest information within the specialty that one is practising. The case based nature of this book, with modality independent content, allows the reader to assimilate practice specific information with ease. Full color images with tabular salient points, imaging algorithms and evidence based criterion support the text. Key points provide succinct explanations of the disease and an appropriate differential diagnosis, as well as providing a brief description of therapy and prognosis. Genitourinary Imaging - A Case Based Approach is aimed at residents and training and practicing genitourinary radiologists.

This unique text provides a comprehensive yet concise review of the various environmental factors and lifestyle choices which impact male fertility, with special emphasis on the mechanisms that contribute to decreased sperm production and impaired function. Internationally recognized scientists and clinicians, leaders in the field of infertility, gather their insights and discuss how to prevent, address and cure male infertility caused by factors such as smoking, alcohol consumption, medication and drug use, obesity, dietary and exercise habits, sexually transmitted infections, psychological stress and occupational exposure to chemicals and radiation. Written in an easy to follow, informal yet scientific style, Male Infertility offers invaluable clinical guidelines for physicians and infertility experts and new data and research of great interest to basic scientists, andrologists and embryologists.

The Urinary System chart presents an overview of the male and female urinary systems. The overall anatomy of bladder, kidney, ureters and urethras are illustrated, and the differences between male and female are compared through side-by-side graphics. Heavy gauge 3ml lamination with sealed edges and two metal eyelets for hanging makes chart highly durable. Write-on/wipe-off with dry erase marker (not included).

Practical Controversies in Medical Management of Stone Disease addresses areas of controversy regarding the evaluation and management of recurrent stone formers and provides the best available evidence to support or refute common common drug and dietary recommendations. Aimed at dispelling common myths about preventative stone treatment, this book provides practical recommendations for the diagnositic evaluation and treatment and recurrent calcium calcium stone formers, but addresses uric acid and cystine stone formers. Written by experts in stone disease, Practical Controversies in Medical Management of Stone Disease is a concise yet comprehensive resource that provides the best, current evidence supporting medical practices regarding kidney stone prevention. The book will be of value to anyone involved in the medical care of patients with kidney stones, including urologists, nephrologists, primary care physicians, and dieticians.

Written entirely by surgical urologists, Surgical Management of Urolithiasis: Percutaneous, Shockwave and Ureteroscopy presents a comprehensive overview of the past, present, and future of surgical techniques, with a focus on educating urologists on the full spectrum of stone procedures. In addition to the technical issues, detailed complications are described. Basic as well as advanced techniques are presented in both a didactic and visual mode with representative endoscopic images and radiographs. Recent advancements which are not routinely a core component of surgical training programs are also covered in detail. Compact and extensively illustrated, Surgical Management of Urolithiasis: Percutaneous, Shockwave and Ureteroscopy is a unique and valuable resource in the field of surgical urolithiasis, essential both for those currently in training and for those already in clinical practice.

This volume provides a comprehensive review and detailed description of surgical techniques for prostate cancer surgery. All aspects are covered, including surgical anatomy and methods of transrectal ultrasound guided prostate biopsies, step-by-step approach techniques for radical prostatectomy, and the latest data on outcomes. Furthermore, limitations as well as tips and tricks are detailed in addition to management of common complications. Lastly, with the increasing use of ablative therapy and brachytherapy, the mechanism of action as well as the keys to obtaining optimal outcomes are illustrated. Surgical Techniques for Prostate Cancer is a concise and valuable resource to surgeons that documents the different approaches to prostate cancer surgery.

Treatment of Benign Prostatic Hyperplasia: Modern Techniques is an up-to-date review of modern techniques used to treat benign prostatic hyperplasia. It provides a comprehensive review of both office and operating room based techniques. Both electrosurgical and laser based techniques are covered. These include high powered 532 nm laser photoselective laser vaporization of the prostate (PVP), holmium laser enucleation/ablation of the prostate (HoLEP/HoLAP), and Bipolar Electrovaporization of the Prostate (Bipolar EVP/Bipolar TURP). In addition, a comprehensive review of office based techniques and future therapies currently being developed is presented. Each of these techniques are presented in a balanced fashion with a focus on modern literature. Treatment of Benign Prostatic Hyperplasia: Modern Techniques will be of great value to Urologists, Urology Residents, Iternists, and Family Practitioners.

Clinical Care Pathways in Andrology provides a valuable resource for understanding clinical decision-making in the context of the predominant male reproductive and sexual disorders for which patients commonly seek evaluation and treatment. Conditions that are less well-known but can be severely bothersome to patients, such as penile sensory loss, are also presented. Based on clinical evidence and expert consensus, practical clinical care pathways are featured for each condition. Each clinical care pathway consists of an algorithm that delineates the overall structure of decision-making for each condition, describes initial clinical presentations, and guides the reader through diagnostic testing and treatment. Furthermore, the volume features annotations that develop key andrological concepts and provide explanations for each step in diagnosis and management. Designed for clarity and ease of use, Clinical Care Pathways in Andrology is a practical and valuable reference for urologists, primary care physicians, and residents who are not specialty trained in andrology.