The past several decades have witnessed an impressive array of
conceptual and techno logical advances in the biomedical sciences.
Much of the progress in this area has developed directly as a
result of new morphology-based methods that have permitted the
assessment of chemical, enzymatic, immunological, and molecular
parameters at the cellular and tissue levels. Additional novel
approaches including laser capture microdissection have also
emerged for the acquisition of homogeneous cell popula tions for
molecular analyses. These methodologies have literally reshaped the
approaches to fundamental biological questions and have also had a
major impact in the area of diagnostic pathology. Much of the
groundwork for the development of morphological methods was estab
th lished in the early part of the 19 century by Francois-Vincent
Raspail, generally acknowledged as the founder of the science of
histochemistry. The earliest work in the field was primarily in the
hands of botanists and many of the approaches to the under standing
of the chemical composition of cells and tissues involved
techniques such as microincineration, which destroyed structural
integrity. The development of aniline th dyes in the early 20
century served as a major impetus to studies of the structural
rather than chemical composition of tissue. Later in the century,
however, the focus returned to the identification of chemical
constituents in the context of intact cell and tissue structure.
General
Imprint: |
HumanaPress
|
Country of origin: |
United States |
Release date: |
December 2010 |
First published: |
2001 |
Editors: |
Ricardo V. Lloyd
|
Dimensions: |
254 x 178 x 23mm (L x W x T) |
Format: |
Paperback
|
Pages: |
422 |
Edition: |
Softcover reprint of hardcover 1st ed. 2001 |
ISBN-13: |
978-1-61737-273-5 |
Categories: |
Books >
Medicine >
Other branches of medicine >
Pathology >
Gross pathology
|
LSN: |
1-61737-273-0 |
Barcode: |
9781617372735 |
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