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Cytokines, Stress, and Depression (Hardcover, 1999 ed.)
Loot Price: R5,629
Discovery Miles 56 290
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Cytokines, Stress, and Depression (Hardcover, 1999 ed.)
Series: Advances in Experimental Medicine and Biology, 461
Expected to ship within 10 - 15 working days
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Cytokines had been characterized in the early eighties as
communication mole cules between immune cells, and between
immunocytes and other peripheral cells, such as fibroblasts and
endothelial cells. They play a key role in the regulation of the
immune response and the coordination of the host response to
infection. Based on these biological properties, nobody would have
predicted that one decade later cytokines would burst upon
neurosciences and permeate into several avenues of current
research. In neurology, the connection between cytokines and
inflammation, and the demonstration of a pivotal role of some of
these molecules in cell death by apoptosis, prompted the
investigation of their involvement in several neurological diseases
involving an inflammatory component, including multiple sclerosis,
brain trauma, stroke, and Alzheimer's disease. This movement
started in the late eighties, and the corresponding field of
research, known as neuroimmunology, is presently booming. In
psychiatry, however, the relationship between cytokines and mental
disorders was much less evident and took longer to materialize. The
first indication that cytokines might be involved in
psychopathology came from cancerology and internal medicine."
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