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Foregut - Function -- Dysfunction (Hardcover)
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Foregut - Function -- Dysfunction (Hardcover)
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Knowledge concerning oesophageal pathophysiology has until recently
lagged far behind that of the pathophysiology of other portions of
the gastrointestinal (GI) tract for reasons that still remain
unclear. Yet, it is the fact that, at least until the last few
decades, interest in the oesophagus was primarily based on
pathologic anatomy. Even today, much remains to be learnt on the
pathophysiology of oesophageal disease. The recent development of
methods of studying both morphology and function of the oesophagus
has resulted in a better understanding of normal and abnormal
oesophageal patterns with a corresponding improvement in treatment,
which is now physiologically, rather than anatomically based. As
customary, the World OESO Congresses are planned to provide each
time a thorough analysis of a specific topic in oesophageal
disease. The 8th World Congress of OESO was devoted to the Foregut:
Function and Dysfunction to emphasise the complex interaction
between the oesophagus and the other portions of the upper GI
tract, either in maintaining physiological function or in
triggering oesophageal disease. The choice is a timely one because
recent investigations have allowed new insights into the
pathophysiology of these complex interactions to be gained. It is
indeed becoming clear that there are intriguing pathophysiological
abnormalities that account for upper GI symptoms and that more
targeted therapy is needed to address the unmet clinical needs.
Within this framework, specific sessions were devoted to disorders
of secretion, of motility as well as of nutrition with a special
emphasis on recent advances. Unlike some of the other publications,
this volume does not merely represent the proceedings of an
International Congress. With its now established and successful
format, it collects the answers to 130 key questions, offered by
110 basic scientists and clinicians the world over, all of whom
have personally contributed to the topic, in order to provide a
glimpse of what may lie ahead. The easy-to-read format will allow
the practising and busy physician to keep up efficiently with
advances in diagnosis and therapy in this rapidly evolving field.
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