The Extracellular Matrix: an Overview (Hardcover, Edition.)

Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series "Biology of Extracellular Matrix" provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function. Content Level Research

General

Imprint:	Springer-Verlag
Country of origin:	Germany
Series:	Biology of Extracellular Matrix
Release date:	February 2011
First published:	2011
Editors:	Robert Mecham
Dimensions:	235 x 155 x 23mm (L x W x T)
Format:	Hardcover
Pages:	426
Edition:	Edition.
ISBN-13:	978-3-642-16554-2
Categories:	Books > Science & Mathematics > Biology, life sciences > Cellular biology > General
LSN:	3-642-16554-0
Barcode:	9783642165542

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