The volume provides an overview of the current status of exocytosis
and to define future goals.
Exocytosis, a universal process of eukaryotic cells, consisting
of the fusion between the vesicle and the plasma membrane is an
important topic in cell biology, physiology, biophysics,
biochemistry and many other disciplines. The understanding of this
rather complex process is essential for the understanding of normal
function of unicellular and multicellular organisms from animal to
plant kingdoms and in pathological conditions as well. During the
last three decades a rapid increase in the number of research
papers addressing this topic have been published.
The development of our understanding of exocytosis spans the
initial evidences that "something is being released" from cells to
the description of extensive physiological, biophysical, molecular
and genetic properties of the process. A list of key proteins
involved in exocytosis in a number of cell types has been
identified, but work is still being done to come to a consensus
about a mechanism or mechanisms that describe the interplay of key
players in functional terms.
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