"Introduction to Biological and Small Molecule Drug Research and
Development "provides, for the first time, an introduction to the
science behind successful pharmaceutical research and development
programs. The book explains basic principles, then compares and
contrasts approaches to both biopharmaceuticals (proteins) and
small molecule drugs, presenting an overview of the business and
management issues of these approaches. The latter part of the book
provides carefully selected real-life case studies illustrating how
the theory presented in the first part of the book is actually put
into practice. Studies include Herceptin/T-DM1, erythropoietin
(Epogen/Eprex/NeoRecormon), anti-HIV protease inhibitor Darunavir,
and more.
"Introduction to Biological and Small Molecule Drug Research and
Development" is intended for late-stage undergraduates or
postgraduates studying chemistry (at the biology interface),
biochemistry, medicine, pharmacy, medicine, or allied subjects. The
book is also useful in a wide variety of science degree courses, in
post-graduate taught material (Masters and PhD), and as basic
background reading for scientists in the pharmaceutical
industry.
For the first time, the fundamental scientific principles of
biopharmaceuticals and small molecule chemotherapeutics are
discussed side-by-side at a basic levelEdited by three senior
scientists with over 100 years of experience in drug research who
have compiled the best scientific comparison of small molecule and
biopharmaceuticals approaches to new drugsIllustrated with key
examples of important drugs that exemplify the basic principles of
pharmaceutical drug research and development
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