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Books > Medicine > Clinical & internal medicine > Musculoskeletal medicine
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Biological Approaches to Spinal Disc Repair and Regeneration for Clinicians (Hardcover)
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Biological Approaches to Spinal Disc Repair and Regeneration for Clinicians (Hardcover)
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Top Experts Share Clinical Insights on Biological Interventions for
Spine-Related Disease Although there have been significant
advancements in minimally invasive spinal surgery techniques in the
last few decades, optimal outcomes for chronic low back pain remain
elusive. A number of promising clinical trials have been conducted
using tissue engineering and biological interventions for disc
degeneration. Written by renowned innovators, this is the first
book that covers implementation of these groundbreaking approaches
for disc disease. The text begins with key fundamentals including
anatomy and physiology, pathophysiology, imaging and biomechanics
to delineate healthy versus diseased spine. Subsequent sections
discuss treatment strategies, research findings, and future
developments. Throughout each chapter, renowned spine surgeons and
scientists share clinical pearls gleaned from hands-on experience.
Key Highlights The current state of the art in biological and
tissue engineering procedures for spinal disorders Treatment
methodologies including nucleus replacement and repair, annulus
fibrosus repair, total disc transplantation, and mechanical total
disc replacement Innovative treatment strategies for disc
regeneration, such as genes and proteins Growth factors including
platelet-rich plasma (PRP), which has shown promise for the
stimulation and acceleration of bone and soft tissue healing
Cell-based therapy for spinal disc regeneration and repair
including the use of stem cells and chondrocytes In-depth
discussion of research including animal versus human model,
in-vitro, and a summary of biologic clinical trials This is a
must-have resource for trainee and practicing orthopaedic surgeons
and neurosurgeons who treat patients for spine-related conditions.
It is essential reading for all clinicians who have an interest in
cutting-edge tissue engineering and biological treatment
interventions.
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