The present study was designed to demonstrate the effect of
monosodium glutamate on PRL level in prepubertal rabbits. Glutamate
is a major neurotransmitter that acts on extensive brain regions,
such as hypothalamus and the pituitary and induce the secretion of
PRL. In this study, young male rabbits (Lates calcarifer) of 3 to 4
months of age were treated with 2mg/g body weight MSG dissolved in
0.9% saline. The animals in control group received equal quantity
of 0.9% saline. Blood samples were collected 15 minutes after
administration of drug, and plasma was separated. All plasma
samples were analyzed by Enzyme linked Immunosorbent Assay (ELISA).
Within the control group, there was no significant difference in
plasma PRL level (p
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