The Development of the Perineum in the Human - A Comprehensive Histological Study with a Special Reference to the Role of the Stromal Components (Paperback, 2005 ed.)

References. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 126 Subject Index. . . . . . . . . . . . . . . . . . . . . . . . . . . . 133 1 Introduction The developmental steps which lead to the formation of the human perineum seem firmly established (Arey 1965; Hamilton and Mossman1972; Moore and Persaud 1998; Wartenberg 1993; Sadler 1995; Larsen 1997). They form the base for the evaluation of the pathogenesis of a great variety of complicated and often serious malformations which occur in this region. This concept has, however, been challenged by the results of an investigation into the n- mal and abnormal development of the anorectum in pig (van der Putte and Neeteson 1983, 1984; van der Putte 1986). Observations revealed that at least in pig, a major element in current ideas about the early development of the perineum, namely the process by which the original simple cloaca is sub- vided into a urogenital and anal part is incorrect, while additional obser- tions strongly suggested that the same may be true for ideas about female and male sexual transformation. A preliminary investigation in human - bryos gave similar indications (van der Putte 1986). The data supported e- lier critical findings (Politzer 1931, 1932; Wijnen 1964; Ludwig 1965) which have apparently been ignored, possibly because they seemed to hinder the understanding of the pathogenesis of congenital malformations such as - perforate anus and hypospadias.

General

Imprint:	Springer-Verlag
Country of origin:	Germany
Series:	Advances in Anatomy, Embryology and Cell Biology, 177
Release date:	October 2004
First published:	2005
Authors:	S.C.J. Van Der Putte
Dimensions:	235 x 155 x 8mm (L x W x T)
Format:	Paperback
Pages:	136
Edition:	2005 ed.
ISBN-13:	978-3-540-21039-9
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Anatomy > Cytology
LSN:	3-540-21039-3
Barcode:	9783540210399

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