Books > Medicine > Clinical & internal medicine > Diseases & disorders > Infectious & contagious diseases > HIV / AIDS
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AIDS and Tuberculosis (Hardcover)
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AIDS and Tuberculosis (Hardcover)
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The immune deficiency AIDS leads to a drastic increase in
susceptibility to Tuberculosis. Accordingly, co-infections of
tuberculosis (TB) and AIDS have increased dramatically over the
last decades and have already killed more than 5 million people
worldwide. Currently, no vaccines are available for either of these
diseases leaving doctors with limited options for prevention. This
perfect storm of pandemics is analysed and explained for the first
time in this groundbreaking title, edited by two of the most
accomplished experts in this area, Prof. Dr. Dr. h.c. Stefan
Kaufmann at the Max-Planck Institute for infectious diseases in
Berlin, Germany, and Prof. Dr. Bruce Walker, director of the Ragon
Institute of MGH, MIT and Harvard in Boston, USA. Co-infection of
AIDS and TB occur frequently in the most impoverished regions of
the world and the AIDS pandemic which has spread rapidly across
Africa over the past two decades is now being met by a TB pandemic.
While TB can be cured and AIDS can be treated, co-infection in a
single patient presents unique challenges and the rapid expansion
of these two pandemics has resulted in a critical need to better
understand the interactions between the two pathogens and to
integrate research efforts. This title brings together scientists
from the forefront of research to explore and combine
state-of-the-art studies in drug interactions and disease
therapies, providing the latest information about prevention,
therapy and diagnosis of both tuberculosis and AIDS. This is the
only book to place a clear emphasis on the increasing number of
patients suffering from both tuberculosis and AIDS and is unique in
combining expertise from both fields. Using a multi-disciplinary
approach the authors bring together the issues surrounding
treatment of co-infection by highlighting the problems of treatment
overlap and providing new data demonstrating exactly how this
deadly liaison plays out. Early chapters focus on immunology and
the problems facing vaccination strategies for both diseases.
Currently no vaccines exist for either disease and the coexistence
of both pathogens in a single patient complicates the research for
new preventive, diagnostic or therapeutic approaches. Later
chapters deal with some of the most threatening consequences of
this co-infection, such as the emergence of drug resistant TB.
These chapters also deal with the need to simultaneously treat both
infections, highlighting the major problem of drug interaction if
two treatments which have been researched in isolation are given to
one individual. Together the contributing authors offer a
refreshingly new and engaging analysis of this most challenging of
topics and offer new therapeutic approaches by providing
comprehensive understanding of both diseases. This title is of
strong interest to a broad range of research communities, from
microbiologists and virologists to immunologists and medical
doctors specializing in TB and AIDS treatment as well as to the
pharmaceutical and biotechnological Industries. Aids and
Tuberculosis: A Deadly Liaison is the first title in
Wiley-Blackwell's 'Infection Biology Handbook Series'. The second
title in the series is Bacterial Virulence: Basic Principles,
Models and Global Approaches , edited by Philippe Sansonetti from
the Pasteur Institute in Paris, France.
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