Molecular Optimization of Calcineurin Inhibitors for Prion Disease (Paperback)

This study mainly emphasizes on pharmacophore features available in the immunosuppressant drugs, especially Calcineurin inhibitors for human prion diseases. The structural and functional properties of FK506/Tacrolimus - a drug used for treatment of human prion diseases were enhanced through pharmacophore-assisted molecular optimization approach. Important pharmacophore features responsible for interaction with active site and intramolecular structural stability were elucidated.

General

Imprint:	Lap Lambert Academic Publishing
Country of origin:	Germany
Release date:	June 2012
First published:	June 2012
Authors:	Saumya Patel • S. Prasanth Kumar • Yogesh T. Jasrai
Dimensions:	229 x 152 x 5mm (L x W x T)
Format:	Paperback - Trade
Pages:	80
ISBN-13:	978-3-659-15895-7
Categories:	Books > Science & Mathematics > Biology, life sciences > General
LSN:	3-659-15895-X
Barcode:	9783659158957

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